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Letters in Drug Design & Discovery

Volume 18, 12 Issues, 2021
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access


Letters in Drug Design & Discovery, Volume 15 - Number 7

Research Article

Synthesis and in vitro Evaluation of 1,2,3-triazole-4-chloromethylcoumarins with Antioxidant Activity

, 15(7): 700 - 705

Anna Carolina Schneider Alves, Thais Munhoz, Fabiana Gomes Nascimento Soares, Liliana Rockenbach, Bruna Gauer, Daniel Fabio Kawano, Gilsane Lino von Poser, Solange Cristina Garcia and Vera Lucia Eifler-Lima*

DOI: 10.2174/1570180814666171011165051

Research Article

Synthesis and Biological Activity of New Schiff Bases of Benzylideneamine Bearing Thiophene, 1,2,4-triazolone, 1,3,4-oxadiazole, Morpholine Moieties

, 15(7): 706 - 712

Yasemin Unver* and Ersan Bektas

DOI: 10.2174/1570180814666171012163651

Research Article

Efficient Synthesis of Ibandronate in the Presence of an Ionic Liquid

, 15(7): 713 - 720

David Illes Nagy, Alajos Grun, Oliver Pavela, Sandor Garadnay, Istvan Greiner and Gyorgy Keglevich*

DOI: 10.2174/1570180814666171027160324

Research Article

3D QSAR Studies of Tricyclic Compounds as Porcupine Inhibitors for Wnt Pathway Inhibitory Activity

, 15(7): 721 - 732

Liqiang Meng, Liqian Sun, Chaoqun Yan, Dongxiao Cui, Jingrun Chen, Taigang Liang* and Qingshan Li*

DOI: 10.2174/1570180814666171002162025

Research Article

Synthesis, Characterization and Antibacterial Evaluation of some New 1,2,4-triazolo[3,4-b][1,3,4]thiadiazines as Potential Antibacterial Agents

, 15(7): 733 - 743

Kooi-Mow Sim* and Kah-Cheng Teo

DOI: 10.2174/1570180814666170922165933

Research Article

Synthesis of New Thiazolyl-Pyrazoline Derivatives and Evaluation of Their Antimicrobial, Cytotoxic and Genotoxic Effects

, 15(7): 744 - 756

Belgin Sever, Mehlika Dilek Altıntop, Hulya Karaca Gencer, Handan Acelya Kapkac, Ozlem Atli, Merve Baysal and Ahmet Ozdemir*

DOI: 10.2174/1570180814666170925152902

Research Article

Novel Hybrid Molecules of Quinazoline Chalcone Derivatives: Synthesis and Study of in vitro Cytotoxic Activities

, 15(7): 757 - 765

Arunkumar Thiriveedhi*, Ratnakaram Venkata Nadh, Navuluri Srinivasu and Kishore Kaushal

DOI: 10.2174/1570180814666171013162148

Research Article

Synthesis, Aqueous Solubility, Metabolic Stability and Pharmacological Profile of Simplified Urea Derivatives

, 15(7): 766 - 777

Raquel de Oliveira Lopes, Marina Amaral Alves, Roberta Olmo Pinheiro, Cristina Setim Freitas, Fernando Q. Cunha, Eliezer J. Barreiro* and Lídia Moreira Lima*

DOI: 10.2174/1570180814666171012155204

Research Article

Synthesis, Pharmacological Evaluation and Docking Study of a New Modulator of Microtubule Polymerization

, 15(7): 778 - 786

Teiliane R. Carneiro, Daniel N. do Amaral, Harold H. Fokoue, Carlos M.R. Sant`Anna, Maria L.G. Porras, Augusto C.A. Oliveira, Bruno C. Cavalcanti, Claudia Pessoa, Eliezer J. Barreiro and Lidia M. Lima*

DOI: 10.2174/1570180814666171012162557

Research Article

Enhancement Antimicrobial Activity of Clarithromycin by Amine Functionalized Mesoporous Silica Nanoparticles as Drug Delivery System

, 15(7): 787 - 795

Pegah Khosravian, Mehdi Khoobi, Mehdi Shafiee Ardestani, Mohammad Porgham Daryasari, Malihe Hassanzadeh, Payam Ghasemi-Dehkordi, Massoud Amanlou and Hamid Akbari Javar*

DOI: 10.2174/1570180815666180117155818

Review Article

Review of Medicinal Plants and their Compounds for Aldose Reductase Inhibitory Activity

, 15(7): 796 - 812

Saliha Bouknana, Mohamed Bouhrim, Hayat Ouassou and Mohamed Bnouham*

DOI: 10.2174/1570180814666171011163954


Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Ivana Cacciatore serves as the Editor-in-Chief of the journal.

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