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Contents

Letters in Drug Design & Discovery, Volume 15 - Number 3


Research Article

Arginine- and Lysine-rich Peptides: Synthesis, Characterization and Antimicrobial Activity

, 15(3): 220 - 226

Adriano Mollica*, Giorgia Macedonio, Azzurra Stefanucci, Roberto Costante, Simone Carradori, Valentina Cataldi, Mara Di Giulio, Luigina Cellini, Romano Silvestri, Cesare Giordano, Anita Scipioni, Stefano Morosetti, Pasqualina Punzi and Sako Mirzaie


DOI: 10.2174/1570180814666170213161341



Research Article

In Vitro Evaluation of the Antibacterial Activity and Antibiotic- Modulatory Effect of Gracilaria cervicornis (Tuner) J. Agardh

, 15(3): 227 - 230

Israeliane F. Cordeiro, Henrique D. M. Coutinho, Joao V. A. Ferreira, Lucindo J. Quintans Junior*, Irwin R. A. Menezes, Micheline A. Lima, Thiago S. Freitas, Maria Isabeli P. Goncalo, Francisco Licaon G. Rocha, Rivio Fabricio de F. Furtado and Jacqueline C. Andrade


DOI: 10.2174/1570180814666170309094910



Research Article

Characterization and Evaluation of the Antioxidant Activity of Calamusenone, a Major Component of Hyptis pectinata (L.) Poit Essential Oil

, 15(3): 231 - 239

Mairim R. Serafini*, Daviane M.C. Vergne, Paula P. Menezes, Joao P.A. Santos, Thallita K. Rabelo, Shanmugam Saravanan, Pericles B. Alves, Emmanoel V. Costa, Hugo Cesar R. Jesus, Marcos J. Salvador, Daniel P. Gelain, Jose C.F. Moreira, Ricardo F. Rocha, Adriano A.S. Araujo* and Lucindo J. Quintans-Junior*


DOI: 10.2174/1570180814666170309130728



Research Article

Solvent-free Mechano-chemical Synthesis of New Omeprazole Derived Metal Complexes: Characterization, Urease Inhibitory Kinetics and Selective Anti-Helicobacter pylori Activity

, 15(3): 240 - 250

Muhammad Amin*, Farooq Anwar, Mahmood Anwar, Abdul Karim, Khalid M. Alkharfy and Anwarul-Hassan Gilani*


DOI: 10.2174/1570180814666170309130030



Research Article

Effects of Asphodeline lutea Compounds on Toxicity Models in Isolated Rat Microsomes and Hepatocytes

, 15(3): 251 - 255

Magdalena Kondeva-Burdina, Rumyana Simeonova, Vessela Vitcheva, Irina Lazarova*, Reneta Gevrenova, Dimitrina Zheleva-Dimitrova, Gokhan Zengin and Nikolay D. Danchev


DOI: 10.2174/1570180814666170306122707



Research Article

Inhibitory Effects of Flavonolignans from Silybum marianum (L.) Gaertn (Milk Thistle) on Function of Aldehyde Oxidase and Xanthine Oxidase in Rats

, 15(3): 256 - 262

Nafiseh Alizadeh, Morteza Eskandani, Khalil Tondro, Mohamad-Reza Rashidi and Hossein Nazemiyeh*


DOI: 10.2174/1570180814666170420110005



Research Article

Chemical Constituent and Biological Activities of Spatoglossum asperum J. Agardh from Oman Sea

, 15(3): 263 - 269

Nasrin Movahhedin*, Hossein Nazemiyeh*, Jaleh Barar, Solmaz Esnaashari and Amir Hossein Movahhedin


DOI: 10.2174/1570180814666170407103936



Research Article

Herbal Medicines: Application of a Sequential Voltammetric Procedure to the Determination of Mercury, Copper, Lead, Cadmium and Zinc at Trace Level

, 15(3): 270 - 280

Dora Melucci, Marcello Locatelli, Francesco De Laurentiis, Gokhan Zengin and Clinio Locatelli*


DOI: 10.2174/1570180814666170412124634



Review Article

Analytical Procedures for Secondary Metabolites Determination: Recent Trends and Future Perspectives

, 15(3): 281 - 293

Luigi Menghini, Giuseppe Bellagamba, Marcelli Fabiana, Elisa De Luca, Luca Armellani, Roberta Cifelli, Arianna Granese, Nilgun Zengin Kucukerkan, Abdurrahman Aktumsek and Gokhan Zengin*


DOI: 10.2174/1570180814666170505124707



Research Article

Novel 11,12H-dihydronaphthalene[1,2-b]quinoline as Atypical Antipsychotic

, 15(3): 294 - 303

Maria Matilde Ramirez Moran, Jorge Eduardo Angel Guio*, Natividad Herrera Cano, Biagina del Carmen Migliore, Rodolfo Izquierdo, Jaime Charris, Simon Lopez, Anita Israel, Ana Santiago, Roberto Rossi, Luis Perdomo, Akram Samear Dabian, Mariagracia Vera Sosa, Alejandra Villalba and Ligia Biagina Angel Migliore


DOI: 10.2174/1570180814666170704144246



Research Article

3D-QSAR Studies of 1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-ones Derivatives as RSV Fusion Inhibitors

, 15(3): 304 - 315

Lian Liu, Yuanhao Zhai, Yiqun Chang, Wen Yan, Ruoshi Huang, Pinghua Sun, Wenzhu Huang* and Jialiang Guo*


DOI: 10.2174/1570180814666170727144943



Research Article

Gastroprotective Activity of Hydroalcoholic Extract of the Stryphnodendron rotundifolium Mart. in Mice: Mechanism Actions Assay

, 15(3): 316 - 324

Dayanne Rakelle de Oliveira, Lucindo Jose Quintans-Junior*, Thais Rodrigues de Albuquerque, Francisco Elizaudo de Brito Junior, Cicera Norma Fernandes, Heloisa Helena Fernandes de Souza, Aline Augusti Boligon, Margareth Linde Athayde, Cicero Bezerra Felipe, Henrique Douglas Melo Coutinho, Roseli Barbosa, Marta Regina Kerntopf and Irwin Rose Alencar de Menezes*


DOI: 10.2174/1570180814666170213154951



Research Article

Antimicrobial, Gastroprotective and Healing Effect of the Hydroalcoholic Extract of Astronium fraxinifolium

, 15(3): 325 - 334

Anita Oliveira Brito Pereira Bezerra Martins, Ana Luiza Albuquerque Siebra, Cicera Datiane de Morais Oliveira, Gerlania Oliveira Leite, Henrique Douglas Melo Coutinho, Margareth Linde Athayde, Aline Augusti Bolignon, Jacqueline Cosmo Andrade, Larissa Rolim Oliveira, Marta Regina Kerntopf, Roseli Barbosa, Francisco Rafael Alves Santana Cesario, Thales Silva Coutinho, Lucindo Jose Quintans-Junior and Irwin Rose Alencar de Menezes*


DOI: 10.2174/1570180814666170213160114




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