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Letters in Drug Design & Discovery

Volume 16, 12 Issues, 2019
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access

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    Chemistry, Medicinal

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Contents

Letters in Drug Design & Discovery, Volume 15 - Number 12


Research Article

Design, Synthesis and Biological Evaluation of Pyrido[2,3-d] Pyrimidine Derivatives as Potential Anticancer Agents

, 15(12): 1240 - 1251

Jamelah S. Al-Otaibi, Diaa A. Ibrahim* and Tarek M. EL Gogary


DOI: 10.2174/1570180815666180219163254



Research Article

Synthesis and Antioxidant Activities of Ferrocenyl-containing Curcumin Analogues

, 15(12): 1252 - 1258

Xianjiao Meng, Shengling Li, Wenbing Ma*, Jianlong Wang, Zhiyong Hu and Duanlin Cao*


DOI: 10.2174/1570180815666180219161110



Research Article

New 1,3-oxazolylphosphonium Salts as Potential Biocides: QSAR Study, Synthesis, Antibacterial Activity and Toxicity Evaluation

, 15(12): 1259 - 1267

Maria M. Trush*, Vasyl Kovalishyn, Alla D. Ocheretniuk, Larisa E. Kalashnikova, Volodymyr M. Prokopenko, Oleksandr V. Holovchenko, Oleksandr L. Kobzar, Volodymyr S. Brovarets and Larisa O. Metelytsia


DOI: 10.2174/1570180815666180219164334



Research Article

Synthesis and Anticancer Properties of Methyl N1-(thien-4-yl)amidrazone- 3-carboxylates

, 15(12): 1268 - 1275

Ali M. Almansour, Jalal A. Zahra*, Salim S. Sabri, Mustafa M. El-Abadelah, Malik A. Zihlif and Mutasem O. Taha


DOI: 10.2174/1570180815666180306152143



Research Article

Synthesis, Characterization and Antimicrobial Activity of Thiamine Complexes

, 15(12): 1276 - 1287

Sumaira Khurshid*, Shazia Shah, Qurrat-ul-Ain, Arshia, Zahida T. Maqsood, Saima Tauseef and Khalid Mohammed Khan*


DOI: 10.2174/1570180815666180321155734



Research Article

Arylsulfonylhydrazone Induced Apoptosis in MDA-MB-231 Breast Cancer Cells

, 15(12): 1288 - 1298

Thais Batista Fernandes, Ricardo Alexandre de Azevedo, Rosania Yang, Sarah Fernandes Teixeira, Gustavo Henrique Goulart Trossini, Jose Alexandre Marzagao Barbuto, Adilson Kleber Ferreira and Roberto Parise-Filho*


DOI: 10.2174/1570180815666180321161513



Research Article

Synthesis, Biological Evaluation and Docking Studies of 1,3,4-Oxadiazole Fused Benzothiazole Derivatives for Anticancer Drugs

, 15(12): 1299 - 1307

Madala Subramanyam, Reddymasu Sreenivasulu, Rambabu Gundla, Mandava V.B. Rao and Koya Prabhakara Rao *


DOI: 10.2174/1570180815666180219165119



Research Article

Preparation and Characterization of GLUT1-mediated Novel Brain Targeting Magnetic Nanoparticles

, 15(12): 1308 - 1313

Li Zhang, Yi Zhao, Qiming Yue, Qiuyi Fu, Li Hai, Li Guo, Qiantao Wang* and Yong Wu*


DOI: 10.2174/1570180815666180322113934



Research Article

Synthesis and Antifungal Activity of Some 6-tert-butyl-8-chloro-2, 3- dimethylquinolin-4-ol Derivatives against Pyricularia oryae

, 15(12): 1314 - 1318

Yue-Ming Fang, Rui-Rui Zhang, Zhong-Hua Shen, Cheng-Xia Tan, Jian-Quan Weng, Tian-Ming Xu*, Xing-Hai Liu*, Hong-Ying Huang and Hong-Ke Wu


DOI: 10.2174/1570180815666180313121735



Research Article

Synthesis, Biological Evaluation and Molecular Docking Studies of Novel Trimethoxy-ring Derivatives as BRD4 Inhibitors

, 15(12): 1319 - 1328

Yan Yang and Zhiyi Yao*


DOI: 10.2174/1570180815666180322115056



Research Article

Molecular Highlights about Leishmanicidal Activity and Cytotoxicity of Quinoxaline Derivatives: A Combination of Ligand-based QSAR/QSTR Approaches

, 15(12): 1329 - 1345

Joseph W. Castro Silva, Aline A. Santos and Edilson B. Alencar Filho*


DOI: 10.2174/1570180815666180322114548



Research Article

Design and Synthesis of Novel 1,3,4-Oxadiazole Derivatives Bearing Azo Moiety as Biologically Significant Scaffolds

, 15(12): 1346 - 1355

Bilal Ahmad Khan*, Safeena Zafar, Ehsan Ullah Mughal*, Muhammad Naeem Ahmed, Syeda Shamila Hamdani, Tashfeen Akhtar, Ihsan-ul-Haq, Amina Sadiq and Khalid Mohammed Khan


DOI: 10.2174/1570180815666180326152204





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