Bentham Science Logo

Track Your Manuscript:


Letters in Drug Design & Discovery

Volume 17, 12 Issues, 2020
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Contents

Letters in Drug Design & Discovery, Volume 15 - Number 11


Research Article

Oxime K033-Reactivation Activity of Cholinesterases Inhibited by Various Nerve Agents and Organophosphorus Pesticides

, 15(11): 1124 - 1130

Kamil Kuca*, Kamil Musilek, Daniel Jun, Jaroslav Pejchal, Ondrej Krejcar, Marek Penhaker, Qinghua Wu, Raquel O. Lopes, Teodorico C. Ramalho, Tanos C.C. Franca, Eugenie Nepovimova and Ondrej Soukup


DOI: 10.2174/1570164615666180713112238



Research Article

Design, Synthesis and Characterization of Novel Urolithin Derivatives as Cholinesterase Inhibitor Agents

, 15(11): 1131 - 1140

Maryam Norouzbahari, Emine V. Burgaz, Tugba Ercetin, Amirhossein Fallah, Alireza Foroumadi, Loghman Firoozpour, Mustafa F. Sahin, Mustafa Gazi and Hayrettin O. Gulcan*


DOI: 10.2174/1570180815666180115144608



Research Article

Synthesis of 1,1’-Ferrocene Diformates Bearing Isoxazole Moiety and Preliminarily Cytotoxicity to A549, HCT116 and MCF-7 Cell Lines

, 15(11): 1141 - 1146

Jianping Yong*, Mingxue Yang, Canzhong Lu* and Xiaoyuan Wu


DOI: 10.2174/1570180815666180306124920



Research Article

Radioprotective Effect of Sinapic Acid Against Genotoxicity and Apoptosis Induced by Ionizing Radiation on Human Lymphocytes

, 15(11): 1147 - 1154

Fatemeh Alizadeh, Mohammad Asghari, Seyedeh Atekeh Torabizadeh, Najmeh Rahmanian, Arash Ghasemi and Seyed Jalal Hosseinimehr*


DOI: 10.2174/1570180815666180219163626



Research Article

Inhibition of DNA Topoisomerases by a Series of Benzoxazoles and their Possible Metabolites

, 15(11): 1155 - 1162

Fatma Zilifdar*, Egemen Foto, Tugba Ertan-Bolelli, Ilkay Yildiz , Esin Aki-Yalcin and Nuran Diril


DOI: 10.2174/1570180815666180124143246



Research Article

Averrhoa bilimbi L. leaf Aqueous Extract Modulates both Cardiac Contractility and Frequency in the Guinea-pig Atrium by the Activation of Muscarinic Receptors

, 15(11): 1163 - 1169

Anne Caroline Oliveira dos Santos, Diego Santos Souza, Thassio Ricardo Ribeiro Mesquita, Jose Evaldo Rodrigues de Menezes-Filho, Ana Paula Duarte Caldas, Americo Azevedo de Souza , Gilmara Beatriz Andrade da Silva , Evaleide Diniz de Oliveira, Leonardo Rodrigues dos Santos and Carla Maria Lins de Vasconcelos*


DOI: 10.2174/1570180815666180125150457



Research Article

6-Methoxy-3,4-dihydronaphthalenone Chalcone-like Derivatives as Potent Tyrosinase Inhibitors and Radical Scavengers

, 15(11): 1170 - 1179

Sara Ranjbar, Abdolhossein Akbari, Najmeh Edraki, Mahsima Khoshneviszadeh, Hajar Hemmatian, Omidreza Firuzi and Mehdi Khoshneviszadeh*


DOI: 10.2174/1570180815666180219155027



Research Article

Oral Bioavailability of Naturally Occurring Anticancer Phytomolecules

, 15(11): 1180 - 1188

Shilpa Sharma, Mansi Gupta, Ashish Sharma and Subhash M. Agarwal *


DOI: 10.2174/1570180815666180109161014



Research Article

Design, Synthesis and Biological Evaluation of Novel Dihydropyrimidine- 2-Thione Derivatives as Potent Antimicrobial Agents: Experimental and Molecular Docking Approach

, 15(11): 1189 - 1201

Ehsan Ullah Mughal*, Amina Sadiq, Muhammad Hamayun, Muhammad Naveed Zafar, Nighat Fatima, Muhammad Arfat Yameen, Syed Aun Muhammad, Amara Mumtaz, Ishtiaq Ahmed and Tehseen Fatima


DOI: 10.2174/1570180815666180209151516



Research Article

Synthesis, In Silico and Antifungal Studies of Novel Thiophene Analogues Containing Pyrazole Ring

, 15(11): 1202 - 1210

Helmi M. Al-Maqtari, Joazaizulfazli Jamalis*, Subhash Chander, Hasnah M. Sirat , Shivalingegowda Naveen, Neratur K. Lokanath, Siti P.M. Bohari, Deepak P. Bhagwat and Murugesan Sankaranarayanan


DOI: 10.2174/1570180815666180328144325



Research Article

Molecular Docking and 3D-QSAR Studies on 7-azaindole Derivatives as Inhibitors of Trk A: A Strategic Design in Novel Anticancer Agents

, 15(11): 1211 - 1223

Adnane Aouidate*, Adib Ghaleb, Mounir Ghamali, Samir Chtita, Abdellah Ousaa, M`barek Choukrad, Abdelouahid Sbai, Mohammed Bouachrine and Tahar Lakhlifi


DOI: 10.2174/1570180815666171229151138



Letter

Synthetic Aspects and First-time Assessment of 2-amino-1,3-selenazoles Against Mycobacterium tuberculosis

, 15(11): 1224 - 1229

Victor Facchinetti, Marcus V.N. De Souza*, Ana C.S. Nery, Stephane L. Calixto, Juliana T. Granato, Elaine S. Coimbra, Maria C.S. Lourenco, Claudia R.B. Gomes and Thatyana R.A. Vasconcelos


DOI: 10.2174/1570180815666180209153925



Letter

Synthesis, Characterization and Evaluation of Gemfibrozil-Stilbene Hybrid as Antioxidant Agent

, 15(11): 1230 - 1238

Rosa Amoroso, Lidia Leporini, Ivana Cacciatore, Lisa Marinelli, Alessandra Ammazzalorso, Isabella Bruno, Barbara De Filippis, Marialuigia Fantacuzzi, Cristina Maccallini, Luigi Menghini, Antonio Di Stefano and Letizia Giampietro*


DOI: 10.2174/1570180815666180321163246




Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

Biography
View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05

Advertisement

How to write and publish your papers in high impact journalsCovid Resource Center

Related Journals

Related eBooks

eBooks Catalog