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Letters in Drug Design & Discovery

Volume 16, 12 Issues, 2019
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access

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    Chemistry, Medicinal

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Contents

Letters in Drug Design & Discovery, Volume 15 - Number 11


Research Article

Oxime K033-Reactivation Activity of Cholinesterases Inhibited by Various Nerve Agents and Organophosphorus Pesticides

, 15(11): 1124 - 1130

Kamil Kuca*, Kamil Musilek, Daniel Jun, Jaroslav Pejchal, Ondrej Krejcar, Marek Penhaker, Qinghua Wu, Raquel O. Lopes, Teodorico C. Ramalho, Tanos C.C. Franca, Eugenie Nepovimova and Ondrej Soukup


DOI: 10.2174/1570164615666180713112238



Research Article

Design, Synthesis and Characterization of Novel Urolithin Derivatives as Cholinesterase Inhibitor Agents

, 15(11): 1131 - 1140

Maryam Norouzbahari, Emine V. Burgaz, Tugba Ercetin, Amirhossein Fallah, Alireza Foroumadi, Loghman Firoozpour, Mustafa F. Sahin, Mustafa Gazi and Hayrettin O. Gulcan*


DOI: 10.2174/1570180815666180115144608



Research Article

Synthesis of 1,1’-Ferrocene Diformates Bearing Isoxazole Moiety and Preliminarily Cytotoxicity to A549, HCT116 and MCF-7 Cell Lines

, 15(11): 1141 - 1146

Jianping Yong*, Mingxue Yang, Canzhong Lu* and Xiaoyuan Wu


DOI: 10.2174/1570180815666180306124920



Research Article

Radioprotective Effect of Sinapic Acid Against Genotoxicity and Apoptosis Induced by Ionizing Radiation on Human Lymphocytes

, 15(11): 1147 - 1154

Fatemeh Alizadeh, Mohammad Asghari, Seyedeh Atekeh Torabizadeh, Najmeh Rahmanian, Arash Ghasemi and Seyed Jalal Hosseinimehr*


DOI: 10.2174/1570180815666180219163626



Research Article

Inhibition of DNA Topoisomerases by a Series of Benzoxazoles and their Possible Metabolites

, 15(11): 1155 - 1162

Fatma Zilifdar*, Egemen Foto, Tugba Ertan-Bolelli, Ilkay Yildiz , Esin Aki-Yalcin and Nuran Diril


DOI: 10.2174/1570180815666180124143246



Research Article

Averrhoa bilimbi L. leaf Aqueous Extract Modulates both Cardiac Contractility and Frequency in the Guinea-pig Atrium by the Activation of Muscarinic Receptors

, 15(11): 1163 - 1169

Anne Caroline Oliveira dos Santos, Diego Santos Souza, Thassio Ricardo Ribeiro Mesquita, Jose Evaldo Rodrigues de Menezes-Filho, Ana Paula Duarte Caldas, Americo Azevedo de Souza , Gilmara Beatriz Andrade da Silva , Evaleide Diniz de Oliveira, Leonardo Rodrigues dos Santos and Carla Maria Lins de Vasconcelos*


DOI: 10.2174/1570180815666180125150457



Research Article

6-Methoxy-3,4-dihydronaphthalenone Chalcone-like Derivatives as Potent Tyrosinase Inhibitors and Radical Scavengers

, 15(11): 1170 - 1179

Sara Ranjbar, Abdolhossein Akbari, Najmeh Edraki, Mahsima Khoshneviszadeh, Hajar Hemmatian, Omidreza Firuzi and Mehdi Khoshneviszadeh*


DOI: 10.2174/1570180815666180219155027



Research Article

Oral Bioavailability of Naturally Occurring Anticancer Phytomolecules

, 15(11): 1180 - 1188

Shilpa Sharma, Mansi Gupta, Ashish Sharma and Subhash M. Agarwal *


DOI: 10.2174/1570180815666180109161014



Research Article

Design, Synthesis and Biological Evaluation of Novel Dihydropyrimidine- 2-Thione Derivatives as Potent Antimicrobial Agents: Experimental and Molecular Docking Approach

, 15(11): 1189 - 1201

Ehsan Ullah Mughal*, Amina Sadiq, Muhammad Hamayun, Muhammad Naveed Zafar, Nighat Fatima, Muhammad Arfat Yameen, Syed Aun Muhammad, Amara Mumtaz, Ishtiaq Ahmed and Tehseen Fatima


DOI: 10.2174/1570180815666180209151516



Research Article

Synthesis, In Silico and Antifungal Studies of Novel Thiophene Analogues Containing Pyrazole Ring

, 15(11): 1202 - 1210

Helmi M. Al-Maqtari, Joazaizulfazli Jamalis*, Subhash Chander, Hasnah M. Sirat , Shivalingegowda Naveen, Neratur K. Lokanath, Siti P.M. Bohari, Deepak P. Bhagwat and Murugesan Sankaranarayanan


DOI: 10.2174/1570180815666180328144325



Research Article

Molecular Docking and 3D-QSAR Studies on 7-azaindole Derivatives as Inhibitors of Trk A: A Strategic Design in Novel Anticancer Agents

, 15(11): 1211 - 1223

Adnane Aouidate*, Adib Ghaleb, Mounir Ghamali, Samir Chtita, Abdellah Ousaa, M`barek Choukrad, Abdelouahid Sbai, Mohammed Bouachrine and Tahar Lakhlifi


DOI: 10.2174/1570180815666171229151138



Letter

Synthetic Aspects and First-time Assessment of 2-amino-1,3-selenazoles Against Mycobacterium tuberculosis

, 15(11): 1224 - 1229

Victor Facchinetti, Marcus V.N. De Souza*, Ana C.S. Nery, Stephane L. Calixto, Juliana T. Granato, Elaine S. Coimbra, Maria C.S. Lourenco, Claudia R.B. Gomes and Thatyana R.A. Vasconcelos


DOI: 10.2174/1570180815666180209153925



Letter

Synthesis, Characterization and Evaluation of Gemfibrozil-Stilbene Hybrid as Antioxidant Agent

, 15(11): 1230 - 1238

Rosa Amoroso, Lidia Leporini, Ivana Cacciatore, Lisa Marinelli, Alessandra Ammazzalorso, Isabella Bruno, Barbara De Filippis, Marialuigia Fantacuzzi, Cristina Maccallini, Luigi Menghini, Antonio Di Stefano and Letizia Giampietro*


DOI: 10.2174/1570180815666180321163246





Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

Biography View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
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