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Letters in Drug Design & Discovery

Volume 18, 12 Issues, 2021
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access


Letters in Drug Design & Discovery, Volume 15 - Number 10

Research Article

Synthesis and Cytotoxicity Evaluation of Novel Tricyclic Dihydropyrazolo [4,3-f][1,2,3]triazolo Diazepines

, 15(10): 1020 - 1025

Chiranjeevi Bingi, Ashok Kale, Yedla Poornachandra, Chityal Ganesh Kumar and Krishnaiah Atmakur*

DOI: 10.2174/1570180815666180222143229

Research Article

Molecular Modeling Studies of Urea-morpholinopyrimidine Analogues as Dual Inhibitors of mTORC1 and mTORC2 Using 3D-QSAR, Topomer CoMFA and Molecular Docking Simulations

, 15(10): 1026 - 1035

Xiaodong Gao, Yujie Ren*, Jianqing Huang and Anjian Pan

DOI: 10.2174/1570180815666180607090956

Research Article

Biological Activities and Docking Studies on Novel Bis 1,4-DHPS Linked to Arene Core via Ether or Ester Linkage

, 15(10): 1036 - 1045

Nada S. Ibrahim, Magda F. Mohamed, Ahmed H. M. Elwahy* and Ismail A. Abdelhamid*

DOI: 10.2174/1570180815666180105162323

Research Article

3D-QSAR Studies on New Benzothiazole-Based Dual Functional Inhibitors of BCR-ABL Kinase Including the T315I Mutant

, 15(10): 1046 - 1056

Shunlai Li, Chaorui Ren, Chenghu Lu, Xiuxiu Li and Hongguang Du*

DOI: 10.2174/1570180815666180105163053

Research Article

Antimicrobial Activities of Synthetic Arylidine Nicotinic and Isonicotinic Hydrazones

, 15(10): 1057 - 1067

Muhammad Hayat, Khalid Mohammed Khan*, Sumayya Saeed, Uzma Salar, Momin Khan, Taimoor Baig, Aqeel Ahmad, Shahnaz Parveen and Muhammad Taha

DOI: 10.2174/1570180814666170914120337

Research Article

Unveiling the Accuracy of Homology Modeling to Elucidate the Structure of GPCRs-HIV Co-receptor-CCR5 as a Case Study

, 15(10): 1068 - 1078

Vadivelu Aanand, Rajendran Anitha, Somarathinam Kanagasabai, Gunalan Seshan, Changdev G. Gadhe and Gugan Kothandan*

DOI: 10.2174/1570180814666171120153956

Research Article

In Vitro Antibacterial and Antifungal Activity and Computational Evaluation of Novel Indole Derivatives Containing 4-Substituted Piperazine Moieties

, 15(10): 1079 - 1086

Tunca Gul Altuntas*, Nilufer Yilmaz, Abdulilah Ece, Nurten Altanlar and Sureyya Olgen

DOI: 10.2174/1570180815666180109161948

Research Article

Synthesis and Antibacterial/Antitubercular/Antioxidant Activities of Compounds Containing Fluoroquinolone Ring Linked to a 4-thiazolidinone Moiety

, 15(10): 1087 - 1094

Tejeswara Rao Allaka, Naresh Kumar Katari, Venkanna Banothu, Srinubabu Maddela, Manojit Pal* and Jaya Shree Anireddy*

DOI: 10.2174/1570180815666171229150032

Research Article

2-Amino Analogues of Alkynyl Substituted 1,4-dihydropyrimidine: Their Synthesis and Evaluation as Potential Antimicrobial/Cytotoxic Agents

, 15(10): 1095 - 1102

V. Mallikarjuna Rao, A. Srinivasa Rao*, P. Ravi Kumar, S. Shobha Rani and Manojit Pal*

DOI: 10.2174/1570180814666171121151921

Review Article

Plant Antioxidants and Mechanisms of Action

, 15(10): 1103 - 1115

Weslley Felix de Oliveira, Priscila Marcelino dos Santos Silva, Luana Cassandra Breitenbach Barroso Coelho* and Maria Tereza dos Santos Correia*

DOI: 10.2174/1570180815666180222142521


Synthesis and Cytotoxic Activity of 2,6-Diarylidenecyclohexanones and their 6-Amino-1,3-dimethyluracil Monoadducts

, 15(10): 1116 - 1122

Erika Madeleyne Ramos-Rivera, Cuauhtemoc Alvarado, Jose D. Solano, Luis Roa de la Fuente, Angeles Dominguez-Rivera, Miguel Angel Vilchis-Reyes* and Miguel Angel Martinez-Urbina*

DOI: 10.2174/1570180815666180105164032


Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Ivana Cacciatore serves as the Editor-in-Chief of the journal.

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