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Letters in Drug Design & Discovery

Volume 17, 12 Issues, 2020
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research


Letters in Drug Design & Discovery, Volume 15 - Number 10

Research Article

Synthesis and Cytotoxicity Evaluation of Novel Tricyclic Dihydropyrazolo [4,3-f][1,2,3]triazolo Diazepines

, 15(10): 1020 - 1025

Chiranjeevi Bingi, Ashok Kale, Yedla Poornachandra, Chityal Ganesh Kumar and Krishnaiah Atmakur*

DOI: 10.2174/1570180815666180222143229

Research Article

Molecular Modeling Studies of Urea-morpholinopyrimidine Analogues as Dual Inhibitors of mTORC1 and mTORC2 Using 3D-QSAR, Topomer CoMFA and Molecular Docking Simulations

, 15(10): 1026 - 1035

Xiaodong Gao, Yujie Ren*, Jianqing Huang and Anjian Pan

DOI: 10.2174/1570180815666180607090956

Research Article

Biological Activities and Docking Studies on Novel Bis 1,4-DHPS Linked to Arene Core via Ether or Ester Linkage

, 15(10): 1036 - 1045

Nada S. Ibrahim, Magda F. Mohamed, Ahmed H. M. Elwahy* and Ismail A. Abdelhamid*

DOI: 10.2174/1570180815666180105162323

Research Article

3D-QSAR Studies on New Benzothiazole-Based Dual Functional Inhibitors of BCR-ABL Kinase Including the T315I Mutant

, 15(10): 1046 - 1056

Shunlai Li, Chaorui Ren, Chenghu Lu, Xiuxiu Li and Hongguang Du*

DOI: 10.2174/1570180815666180105163053

Research Article

Antimicrobial Activities of Synthetic Arylidine Nicotinic and Isonicotinic Hydrazones

, 15(10): 1057 - 1067

Muhammad Hayat, Khalid Mohammed Khan*, Sumayya Saeed, Uzma Salar, Momin Khan, Taimoor Baig, Aqeel Ahmad, Shahnaz Parveen and Muhammad Taha

DOI: 10.2174/1570180814666170914120337

Research Article

Unveiling the Accuracy of Homology Modeling to Elucidate the Structure of GPCRs-HIV Co-receptor-CCR5 as a Case Study

, 15(10): 1068 - 1078

Vadivelu Aanand, Rajendran Anitha, Somarathinam Kanagasabai, Gunalan Seshan, Changdev G. Gadhe and Gugan Kothandan*

DOI: 10.2174/1570180814666171120153956

Research Article

In Vitro Antibacterial and Antifungal Activity and Computational Evaluation of Novel Indole Derivatives Containing 4-Substituted Piperazine Moieties

, 15(10): 1079 - 1086

Tunca Gul Altuntas*, Nilufer Yilmaz, Abdulilah Ece, Nurten Altanlar and Sureyya Olgen

DOI: 10.2174/1570180815666180109161948

Research Article

Synthesis and Antibacterial/Antitubercular/Antioxidant Activities of Compounds Containing Fluoroquinolone Ring Linked to a 4-thiazolidinone Moiety

, 15(10): 1087 - 1094

Tejeswara Rao Allaka, Naresh Kumar Katari, Venkanna Banothu, Srinubabu Maddela, Manojit Pal* and Jaya Shree Anireddy*

DOI: 10.2174/1570180815666171229150032

Research Article

2-Amino Analogues of Alkynyl Substituted 1,4-dihydropyrimidine: Their Synthesis and Evaluation as Potential Antimicrobial/Cytotoxic Agents

, 15(10): 1095 - 1102

V. Mallikarjuna Rao, A. Srinivasa Rao*, P. Ravi Kumar, S. Shobha Rani and Manojit Pal*

DOI: 10.2174/1570180814666171121151921

Review Article

Plant Antioxidants and Mechanisms of Action

, 15(10): 1103 - 1115

Weslley Felix de Oliveira, Priscila Marcelino dos Santos Silva, Luana Cassandra Breitenbach Barroso Coelho* and Maria Tereza dos Santos Correia*

DOI: 10.2174/1570180815666180222142521


Synthesis and Cytotoxic Activity of 2,6-Diarylidenecyclohexanones and their 6-Amino-1,3-dimethyluracil Monoadducts

, 15(10): 1116 - 1122

Erika Madeleyne Ramos-Rivera, Cuauhtemoc Alvarado, Jose D. Solano, Luis Roa de la Fuente, Angeles Dominguez-Rivera, Miguel Angel Vilchis-Reyes* and Miguel Angel Martinez-Urbina*

DOI: 10.2174/1570180815666180105164032


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05


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