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Letters in Drug Design & Discovery

Volume 17, 12 Issues, 2020
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research


Letters in Drug Design & Discovery, Volume 14 - Number 7

Research Article

A Facile Synthesis and Drug Design of Some New Heterocyclic Compounds Incorporating Pyridine Moiety and Their Antimicrobial Evaluation

, 14(7): 752 - 762

Fathy M. Abdelrazek, Sobhi M. Gomha*, Aly H. Abdelrahman, Peter Metz and Mohsen A. Sayed

DOI: 10.2174/1570180814666161128120240

Research Article

Novel Chromeno[2,3-d]pyrimidines-Design, Synthesis and Antioxidant Activity

, 14(7): 763 - 772

Kotiah Yalagala, Sreekantha B. Jonnalagadda*, Suresh Maddila, Surjyakanta Rana and Surya Narayana Maddila

DOI: 10.2174/1570180814666161123143637

Research Article

Design, Synthesis, Antioxidant and Anticancer Activity of New Coumarin Derivatives Linked with Thiazole, Isoxazole or Pyrazole Moiety

, 14(7): 773 - 781

Khaled R. A. Abdellatif*, Mohamed A. Abdelgawad, Heba A. H. Elshemy, Nesma M. Kahk and Dalia M. El Amir

DOI: 10.2174/1570180813666161026153743

Research Article

In vitro and In silico Analysis of β-lactam Derivatives as Antimycobacterial Agents

, 14(7): 782 - 786

Julieta Luna-Herrera, Edgar E. Lara-Ramirez, Ana R. Munoz-Duarte, Fabian E. Olazaran, Manuel J. Chan-Bacab, Rosa Moo-Puc, Alondra M. Perez-Vazquez, Cynthia M. Morales-Reyes and Gildardo Rivera*

DOI: 10.2174/1570180814666170106111316

Research Article

Synthesis, Enzyme Assays and Molecular Docking Studies of Fluorina ted Bioisosteres of Santacruzamate A as Potential HDAC Tracers

, 14(7): 787 - 797

Muneer Ahamed, Koen Vermeulen, Michael Schnekenburger, Lise Roman Moltzau, Finn Olav Levy, Janos Marton, Mathy Froeyen, Dag Erlend Olberg, Marc Diederich and Guy Bormans

DOI: 10.2174/1570180813666161101152943

Research Article

3D-QSAR Studies of HDAC6 Inhibitors Using Docking-Based Alignment

, 14(7): 798 - 810

Chunqi Hu, Liang Hong, Jun Li and Wenting Du*

DOI: 10.2174/1570180813666161028165151

Research Article

Inhibition of Product Template (PT) Domain of Aflatoxin Producing Polyketide Synthase Enzyme of Aspergillus parasiticus

, 14(7): 811 - 818

Maneesh Kumar, Sindhuprava Rana, Harish Kumar, Jainendra Kumar, Rani Mansuri and Ganesh Chandra Sahoo*

DOI: 10.2174/1570180814666170203144914

Research Article

Tranylcypromine Attenuates Senescence in Dental Pulp Stem Cells

, 14(7): 819 - 826

Junjun Liu, Zhi Liu, Chunyan Wang, Fang Yu, Wenping Cai, Xi Lu, Rongbin Wei, Shouliang Zhao, Yumei Zhao* and Shangfeng Liu*

DOI: 10.2174/1570180814666161229165048

Research Article

Nano Conjugated PLGA-Chlorambucil: Synthesis In Vitro Anti Non- Hodgkin's Lymphoma Cellular Assay

, 14(7): 827 - 836

Saeed Akbarian, Jafar Sojoodi, Fatemeh Monnavari, Hossein Heidari, Pegah Khosravian, Hamid A. Javar, Artin Assadi, Rahimeh Rasouli, Mostafa Saffari, Seyed A.S. Shandiz, Hadi Hejazinia, Farnoor D. Omoomi, Mohammad Saffari and Mehdi S. Ardestani*

DOI: 10.2174/1570180814666161130113446

Research Article

Extended-release Formulation Attenuates the Impacts of Fluvastatin on Serum PCSK9 Levels in Humans

, 14(7): 837 - 842

Yuan-Lin Guo, Wei Zhang, Qian Dong, Geng Liu, Cheng-Gang Zhu, Jing Sun, Rui-Xia Xu and Jian-Jun Li*

DOI: 10.2174/1570180814666161216121558

Research Article

Hydroxamate Inhibitor Profiling of Both Zn2+- and Ni2+-Activated Glyoxalase I Metalloenzymes Having Diverse Quaternary Structures

, 14(7): 843 - 852

Uthaiwan Suttisansanee and John F. Honek*

DOI: 10.2174/1570180814666161128115808

Research Article

Polyphenolic Compound from Vitis vinifera L. have Potential for the Alzheimer Disease Treatment

, 14(7): 853 - 859

Soukup Ondrej, Stralkova Radomira, Mistova Tereza, Popov Marek, Hejtmankova Alena, Lachman Jaromir, Klimova Blanka and Kuca Kamil*

DOI: 10.2174/1570180814666161116112300


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

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Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05


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