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Letters in Drug Design & Discovery

Volume 17, 12 Issues, 2020
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Contents

Letters in Drug Design & Discovery, Volume 14 - Number 6


Research Article

Synthesis, Structural Studies and Biological Evaluation of Halogen Derivatives of 1,3-Disubstituted Thiourea

, 14(6): 636 - 646

Anna Bielenica, Karolina Stepien, Aleksandra Sawczenko, Tadeusz Lis, Anna E. Koziol, Silvia Madeddu, David Collu, Filippo Iuliano, Anita Kosmider and Marta Struga


DOI: 10.2174/1570180814666170106121025



Research Article

Synthesis, Computational Study, and Evaluation of In Vitro Antimicrobial, Antibiofilm, and Anticancer Activities of New Sulfanyl Aminonaphthoquinone Derivatives

, 14(6): 647 - 661

Nilufer Bayrak, Hatice Yıldırım, Amac Fatih Tuyun, Emel Mataraci Kara, Berna Ozbek Celik, Girish Kumar Gupta, Halil I. Ciftci, Mikako Fujita, Masami Otsuka and Hamid R. Nasiri


DOI: 10.2174/157018081406170606155530



Research Article

Synthesis and Antiproliferative Activities of Novel O-Benzyl Salicylamide Derivatives

, 14(6): 662 - 671

Jan Dusek, Ales Imramovsky, Karel Pauk, Radek Jorda, Eva Reznickova and Vladimir Krystof


DOI: 10.2174/1570180813666161020113827



Research Article

Synthesis and Evaluation of New Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents

, 14(6): 672 - 677

Zafer Asım Kaplancıklı, Belgin Sever, Mehlika Dilek Altıntop, Ozlem Atlı, Merve Baysal and Ahmet Ozdemir


DOI: 10.2174/1570180814666161104161711



Research Article

Synthesis and Evaluation of Anti-Tuberculosis and Anti-Cancer Activities of Hydrazones and N-Acylhydrazones by Using Sonochemistry, A New General Procedure

, 14(6): 678 - 685

Ligia Souza da Silveira Pinto, Marcus V. N. de Souza and Carlos R. Kaiser


DOI: 10.2174/1570180814666161121120414



Research Article

Pharmacodynamic Evaluation of Novel Tetrandrine-loaded Chitosan Microspheres

, 14(6): 686 - 689

Kefang Guo and Jing Cang


DOI: 10.2174/1570180814666170109152252



Research Article

Molecular Docking, Synthesis and CNS Activity of Some Novel 1, 4-Benzodiazepine Derivatives

, 14(6): 690 - 698

Sunil S. Menghani, Rupesh Chikhale, Amit Pant, Bijo Mathew and Pramod Khedekar


DOI: 10.2174/1570180814666170109153441



Research Article

Antitubercular and Antimicrobial Activity of NH4VO3 Promoted 1,4- Dihydropyridine Incorporated 1,3,4-trisubstituted Pyrazole

, 14(6): 699 - 711

Nandam Harikrishna, Arun M. Isloor, K. Ananda, Tanya Parish, Joazaizulfazli Jamalis, Hazem A. Ghabbour and Hoong-Kun Fun


DOI: 10.2174/1570180813666161103145224



Research Article

Novel Indole-Isoxazole Hybrids: Synthesis and In Vitro Anti-Cholinesterase Activity

, 14(6): 712 - 717

Fahimeh Vafadarnejad, Mina Saeedi, Mohammad Mahdavi, Ali Rafinejad, Elahe Karimpour-Razkenari, Bilqees Sameem, Mahnaz Khanavi and Tahmineh Akbarzadeh


DOI: 10.2174/1570180813666161018124726



Research Article

Withania somnifera Phytochemicals Confer Neuroprotection by Inhibition of the Catalytic Domain of Human Matrix Metalloproteinase-9

, 14(6): 718 - 726

Gaurav Kumar, Pankaj Paliwal and Ranjana Patnaik


DOI: 10.2174/1570180814666161121111811



Research Article

Homology Modeling of Human Nicotinamide/Nicotinic Acid Mononucleotide Adenylyltransferase 2: Insights into Isoenzyme-Specific Differences Using Molecular Docking Simulatons

, 14(6): 727 - 736

Gokcen Eren


DOI: 10.2174/1570180814666161110112859



Research Article

L-carnitine Supplementation Improves Self-rating Depression Scale Scores in Uremic Male Patients Undergoing Hemodialysis

, 14(6): 737 - 742

Kyoko Tashiro, Yusuke Kaida, Sho-ichi Yamagishi, Hideharu Tanaka, Miyuki Yokoro, Junko Yano, Kazuko Sakai, Yuka Kurokawa, Kensei Taguchi, Yosuke Nakayama, Takahiro Inokuchi and Kei Fukami


DOI: 10.2174/1570180814666170216102632



Research Article

Alzheimer’s Disease Drugs- In Vitro Comparison of Cholinesterase Inhibition and beta-amyloid Modulation

, 14(6): 743 - 750

Ondrej Holas, Jan Korabecny, Zuzana Gazova, Katarina Siposova, Kamil Musilek, Veronika Opletalova, Lukas Gorecki, Eugenie Nepovimova, Katarina Spilovska, Eva Mezeiova and Kamil Kuca


DOI: 10.2174/1570180814666161228143846




Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

Biography
View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05

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