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Letters in Drug Design & Discovery

Volume 17, 12 Issues, 2020
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Contents

Letters in Drug Design & Discovery, Volume 13 - Number 8

Effect of Substituted Benzimidazoles and Somatostatin Analogs on the Vitality of Tumor Cell Lines and on the Oxidative Burst of Phagocytes

, 13(8): 725 - 728

Ivan Goshev, Emilia Naydenova, Svetlana Staykova, Anelia Mavrova, Ljubomir Vezenkov and Diana Wesselinova


DOI: 10.2174/1570180813999160429112829



Design, Synthesis and Biological Evaluation of Novel Tamibarotene Derivative as Multitarget Anticancer Agent

, 13(8): 729 - 733

Yuqi Jiang, Jinning Hou, Xiaoyang Li, Wenfang Xu and Yingjie Zhang


DOI: 10.2174/157018081308160826182531



Cytotoxicity of Hydrazones of Morpholine Bearing Mannich Bases Towards Huh7 and T47D Cell Lines and Their Effects on Mitochondrial Respiration

, 13(8): 734 - 741

Kaan Kucukoglu, Halise Inci Gul, Mustafa Gul, Rengul Cetin-Atalay, Yosra Baratli and Bernard Geny


DOI: 10.2174/1570180813666160113002907



Melanogenesis and Melanosome Transportation Modulators from Medicinal Plants

, 13(8): 742 - 751

Kosei Yamauchi and Tohru Mitsunaga


DOI: 10.2174/157018081308160826183039



Pharmacokinetics of Selegiline in a Rabbit Model

, 13(8): 752 - 756

Huba Kalász, Kornélia Tekes, Zita Pöstényi, Eszter Vizvári, Péter Sótonyi, Dóra Szabó and Edit Tóth-Molnár


DOI: 10.2174/1570180813666160125224604



QSAR and Molecular Modeling Studies on a Series of Indole-based Pyridone Analogues as HCV NS5B Polymerase Inhibitors

, 13(8): 757 - 770

Neelu Singh, Basheerulla Shaik, Neeraj Agrawal, Anita K, Vijay K. Agrawal and Satya P. Gupta


DOI: 10.2174/1570180813666160815122359



Effect of Hydrophilic Excipients on Cyclodextrin Complexes of Acyclovir in Improving Solubility, Dissolution and Permeability

, 13(8): 771 - 780

Madhuri Maher, Mukesh Pandey, Lokesh Adhikari, Ajay Semalty and Mona Semalty


DOI: 10.2174/1570180813666160517161058



Design and Evaluation of Microwave Induced Solid Dispersion of Tinidazole and Molecular Modelling with β-cyclodextrin

, 13(8): 781 - 792

Swati Jagdale, Anish Kulkarni, Anuruddha Chabukswar and Bhanudas Kuchekar


DOI: 10.2174/1570180813999160429113650



Synthesis and Biological Evaluation of New imidazo[1,2-a]pyridine Derivatives as Selective COX-2 Inhibitors

, 13(8): 793 - 799

Mahsa Azami Movahed, Bahram Daraei and Afshin Zarghi


DOI: 10.2174/1570180813666160613090944



Synthesis and Evaluation of Anticonvulsant Activities of Pyrazol yl Semicarbazones. Part II

, 13(8): 800 - 808

Ming-Xia Song, Yi Wu and Xian-Qing Deng


DOI: 10.2174/1570180813666160711155752



Design, Synthesis and Bioactivity Evaluation of Novel Dabigatran Derivatives as Potential Thrombin Inhibitors

, 13(8): 809 - 817

Qianqian Liu, Yujie Ren and Xiaodong Gao


DOI: 10.2174/1570180813666160622081105



Synthesis of 2-, 3- or 4-phenylsubtituted Chalcones Based on 4- phenylamino-6-nitro-2-[(E)-2-phenylvinyl]quinoline, Evaluation of their Antimicrobial and Antifungal Activity

, 13(8): 818 - 823

Sulochana Mudaliar, Kishor H. Chikhalia and Nisha K. Shah


DOI: 10.2174/1570180812666151016205033



In silico Strategies to Probe Stereoselective Interactions of Multidrug Resistant Transporter P-glycoprotein

, 13(8): 824 - 832

Ishrat Jabeen


DOI: 10.2174/1570180813999160429112620



Synthesis and Anticonvulsant Activity of Novel 3-(2-(4H-1,2,4-triazol-4- yl)ethyl)-1-alkyl-1H-indole Derivatives

, 13(8): 833 - 839

Chuan-Feng Liu, Hong-Jian Zhang and Zhe-Shan Quan


DOI: 10.2174/1570180813666160324173717



In silico Modeling Studies of 5-HT2B Antagonistic Activity of 2-(2- phenylethyl)chromone Derivatives from Cucumis melo Seeds

, 13(8): 840 - 844

Sabrin R. M. Ibrahim, Gamal A. Mohamed and Shahenda M. El-Messery


DOI: 10.2174/1570180813666160517164432




Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

Biography View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05

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