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Letters in Drug Design & Discovery

Volume 18, 12 Issues, 2021
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research


Letters in Drug Design & Discovery, Volume 13 - Number 8

Effect of Substituted Benzimidazoles and Somatostatin Analogs on the Vitality of Tumor Cell Lines and on the Oxidative Burst of Phagocytes

, 13(8): 725 - 728

Ivan Goshev, Emilia Naydenova, Svetlana Staykova, Anelia Mavrova, Ljubomir Vezenkov and Diana Wesselinova

DOI: 10.2174/1570180813999160429112829

Design, Synthesis and Biological Evaluation of Novel Tamibarotene Derivative as Multitarget Anticancer Agent

, 13(8): 729 - 733

Yuqi Jiang, Jinning Hou, Xiaoyang Li, Wenfang Xu and Yingjie Zhang

DOI: 10.2174/157018081308160826182531

Cytotoxicity of Hydrazones of Morpholine Bearing Mannich Bases Towards Huh7 and T47D Cell Lines and Their Effects on Mitochondrial Respiration

, 13(8): 734 - 741

Kaan Kucukoglu, Halise Inci Gul, Mustafa Gul, Rengul Cetin-Atalay, Yosra Baratli and Bernard Geny

DOI: 10.2174/1570180813666160113002907

Melanogenesis and Melanosome Transportation Modulators from Medicinal Plants

, 13(8): 742 - 751

Kosei Yamauchi and Tohru Mitsunaga

DOI: 10.2174/157018081308160826183039

Pharmacokinetics of Selegiline in a Rabbit Model

, 13(8): 752 - 756

Huba Kalász, Kornélia Tekes, Zita Pöstényi, Eszter Vizvári, Péter Sótonyi, Dóra Szabó and Edit Tóth-Molnár

DOI: 10.2174/1570180813666160125224604

QSAR and Molecular Modeling Studies on a Series of Indole-based Pyridone Analogues as HCV NS5B Polymerase Inhibitors

, 13(8): 757 - 770

Neelu Singh, Basheerulla Shaik, Neeraj Agrawal, Anita K, Vijay K. Agrawal and Satya P. Gupta

DOI: 10.2174/1570180813666160815122359

Effect of Hydrophilic Excipients on Cyclodextrin Complexes of Acyclovir in Improving Solubility, Dissolution and Permeability

, 13(8): 771 - 780

Madhuri Maher, Mukesh Pandey, Lokesh Adhikari, Ajay Semalty and Mona Semalty

DOI: 10.2174/1570180813666160517161058

Design and Evaluation of Microwave Induced Solid Dispersion of Tinidazole and Molecular Modelling with β-cyclodextrin

, 13(8): 781 - 792

Swati Jagdale, Anish Kulkarni, Anuruddha Chabukswar and Bhanudas Kuchekar

DOI: 10.2174/1570180813999160429113650

Synthesis and Biological Evaluation of New imidazo[1,2-a]pyridine Derivatives as Selective COX-2 Inhibitors

, 13(8): 793 - 799

Mahsa Azami Movahed, Bahram Daraei and Afshin Zarghi

DOI: 10.2174/1570180813666160613090944

Synthesis and Evaluation of Anticonvulsant Activities of Pyrazol yl Semicarbazones. Part II

, 13(8): 800 - 808

Ming-Xia Song, Yi Wu and Xian-Qing Deng

DOI: 10.2174/1570180813666160711155752

Design, Synthesis and Bioactivity Evaluation of Novel Dabigatran Derivatives as Potential Thrombin Inhibitors

, 13(8): 809 - 817

Qianqian Liu, Yujie Ren and Xiaodong Gao

DOI: 10.2174/1570180813666160622081105

Synthesis of 2-, 3- or 4-phenylsubtituted Chalcones Based on 4- phenylamino-6-nitro-2-[(E)-2-phenylvinyl]quinoline, Evaluation of their Antimicrobial and Antifungal Activity

, 13(8): 818 - 823

Sulochana Mudaliar, Kishor H. Chikhalia and Nisha K. Shah

DOI: 10.2174/1570180812666151016205033

In silico Strategies to Probe Stereoselective Interactions of Multidrug Resistant Transporter P-glycoprotein

, 13(8): 824 - 832

Ishrat Jabeen

DOI: 10.2174/1570180813999160429112620

Synthesis and Anticonvulsant Activity of Novel 3-(2-(4H-1,2,4-triazol-4- yl)ethyl)-1-alkyl-1H-indole Derivatives

, 13(8): 833 - 839

Chuan-Feng Liu, Hong-Jian Zhang and Zhe-Shan Quan

DOI: 10.2174/1570180813666160324173717

In silico Modeling Studies of 5-HT2B Antagonistic Activity of 2-(2- phenylethyl)chromone Derivatives from Cucumis melo Seeds

, 13(8): 840 - 844

Sabrin R. M. Ibrahim, Gamal A. Mohamed and Shahenda M. El-Messery

DOI: 10.2174/1570180813666160517164432


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)
View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05



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