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Letters in Drug Design & Discovery

Volume 18, 12 Issues, 2021
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research


Letters in Drug Design & Discovery, Volume 13 - Number 5

Design, Synthesis and ex vivo Study of the Vasorelaxant Activity Induced by Isosteric Derivatives of Dihydropyridines (NH →O)

, 13(5): 353 - 359

Priscila Rendón-Vallejo, Samuel Estrada-Soto, Miguel A. Vázquez, Fernando Hernández- Borja, Rafael Villalobos-Molina and Maximiliano Ibarra-Barajas

DOI: 10.2174/1570180812666151003002501

Flexibility in the Molecular Design of Acetylcholinesterase Reactivators: Probing Representative Conformations by Chemometric Techniques and Docking/QM Calculations

, 13(5): 360 - 371

Willian E.A. de Lima, Ander F. Pereira, Alexandre A. de Castro, Elaine F.F. da Cunha and Teodorico C. Ramalho

DOI: 10.2174/1570180812666150918191550

TRISOXIME – a Bulky Trisquaternary Reactivator of Acetylcholinesterase

, 13(5): 372 - 375

Kamil Kuca, Kamil Musilek and Daniel Jun

DOI: 10.2174/1570180812666150923235240

CoMFA/CoMSIA and Molecular Docking Studies of Novel Matrix Metalloproteinase- 2 Inhibitors Based on L-tyrosine Scaffold

, 13(5): 376 - 386

Jun-Zhang, Xue-Jiao Wang, Zhen-Ke Dong, Shu-Qing Wang, Wei-Ren Xu, Jing-Wei Fu, Xian- Chao Cheng and Run-Ling Wang

DOI: 10.2174/1570180812666150923235104

Prediction of Acridinones’ Ability to Interstrand DNA Crosslinks Formation Using Connected QSRR and QSAR Analysis

, 13(5): 387 - 394

Paulina Szatkowska-Wandas and Marcin Koba

DOI: 10.2174/1570180812666151003001801

Synthesis, Neuro-protection and Anti-cancer Activities of Simple Isatin Mannich and Schiff Bases

, 13(5): 395 - 400

Gang Chen, Yang Ning, Wei Zhao, Yanqiu Zhang, Yu Zhang, Xiaojiang Hao, Ye Wang and Shuzhen Mu

DOI: 10.2174/1570180812666150907203342

Modified Hummel-Dreyer Method and Molecular Modeling Studies Identified Nicotinic Acid Analogues as Carbonic Anhydrase III Ligands

, 13(5): 401 - 410

Nada Jarrar, Muhammed Alzweiri, Yusuf Al-Hiari, Shrouq Farah and Mohammad A. Khanfar

DOI: 10.2174/1570180812666150821002900

Antinociceptive Activities of Some 4,5-Dihydro-1H-Pyrazole Derivatives: Involvement of Central and Peripheral Pathways

, 13(5): 411 - 417

Özgür Devrim Can, Feyza Alyu, Nazlı Turan and Ahmet Özdemir

DOI: 10.2174/1570180812666150819003950

In vitro Study of Furazano[3,4-b]quinoxaline 1-Oxides as Potential ΝΟ Releasing Agents

, 13(5): 418 - 421

Kosmas I. Stoitsis, Petros Gkizis, Emmanouella Basgiouraki, John K. Gallos and Dimitra Hadjipavlou-Litina

DOI: 10.2174/1570180812666150923235828

Relationship Between Carbapenems Structure and Minimal Inhibitory Concentration Selected Bacterial Strains

, 13(5): 422 - 428

Monika Marczak and Tomasz Grabowski

DOI: 10.2174/1570180812666150820234022

Design, Synthesis and Mode of Action of Some New 2-(4'-aminophenyl) benzothiazole Derivatives as Potent Antimicrobial Agents

, 13(5): 429 - 437

Meenakshi Singh, Sudhir Kumar Singh, Mayank Gangwar, Satheeshkumar Sellamuthu, Gopal Nath and Sushil K. Singh

DOI: 10.2174/1570180812666150821003220

Accumulation Effects of Salicylic acid Saccharide Carboxylate on the Alkaloids in Catharanthus roseus Cells

, 13(5): 438 - 440

Er-Bing Yang, Yong Wang, Hong-Jun Zang, Zheng-Ming Li and Xing-Hai Liu

DOI: 10.2174/1570180812666150818235025

Endothelium Dependent and Independent Mechanisms of Vasorelaxant Activity of Synthesized 2,5-disubstituted-1,3,4-oxadiazole Derivatives in Rat Thoracic Aorta – Ex vivo and Molecular Docking Studies

, 13(5): 441 - 450

Zenab Attari, Jayesh Mudgal, Pawan G Nayak, Nandakumar Krishnadas, Revathi Rajappan and N. Gopalan Kutty

DOI: 10.2174/1570180812666150907203634

Despite an Extensive Sequence Analysis Identification of Functional Candidates Amongst Hypothetical Proteins of Neisseria gonorrhoeae

, 13(5): 451 - 464

Kundan Kumar, Amresh Prakash, Asimul Islam, Faizan Ahmad and Md. Imtaiyaz Hassan

DOI: 10.2174/1570180812666150901223055

Sunscreening and Photosensitizing Properties of Coumarins and their Derivatives

, 13(5): 465 - 474

Kinga Kasperkiewicz, Anna Erkiert-Polguj and Elzbieta Budzisz

DOI: 10.2174/1570180812666150901222106


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)
View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05



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