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Letters in Drug Design & Discovery

Volume 17, 12 Issues, 2020
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Contents

Letters in Drug Design & Discovery, Volume 12 - Number 6


First Efficient Two-Step/One-Pot Zirconium (IV)isopropoxide–Mediated Reductive Amination of Carbonyl Compounds

, 12(6): 448 - 456

Cyril Pieri and Jean Michel Brunel


DOI: 10.2174/1570180812666141215215120



FeCl3/Ultrasound Mediated Reaction of 2-aminothiophenol with Aldehydes in Water: Synthesis of 2-substituted Benzothiazoles of Pharmacological Interest

, 12(6): 457 - 465

Ponasanapalli Tirumala Venkata Ankayya Srinivas, Sallagundla Bhavani, Dandela Rambabu, Mandava Venkata Basaveswara Rao, Ravikumar Kapavarapu and Manojit Pal


DOI: 10.2174/1570180812666141216211045



Synthesis of Six Phenylalanine Derivatives and their Cell Toxicity Effect on Human Colon Cancer Cell Line HT-29

, 12(6): 466 - 470

Qianyi Zhao, Ting Xu, Menghua Li, Ying Yang, Haopeng Hu, Shupei Wang, Wenjuan Yan, Ran Chen, Chunyan Zhang and Cunshuan Xu


DOI: 10.2174/1570180812666141206001604


Synthesis and Antitumor Activity of New Pyrimidine and Caffeine Derivatives

, 12(6): 471 - 478

Ameen Ali Abu-Hashem and Hoda Abdel Raouf Hussein


DOI: 10.2174/1570180812666150429234237



De Novo Design of High Potent DPP-IV Inhibitors Based on the Scaffold of Cyanopyrrolidine

, 12(6): 479 - 487

Yu-Lei Jiang, Hao-Liang Yuan, Wei-Wei Zhang, Hai-Chun Liu, Yan-Min Zhang, Xiao Xiong, Jin-Xing Xu, Shuai Lu, Tao Lu and Ya-Dong Chen


DOI: 10.2174/1570180812666141201223016



Biological Evaluation of Halogenated Thioureas as Cholinesterases Inhibitors Against Alzheimer’s Disease & Molecular Modeling Studies

, 12(6): 488 - 494

Jamshed Iqbal, Sumera Zaib, Aamer Saeed and Muhammad Muddassar


DOI: 10.2174/1570180812666141201222247



Novel Fatty Acid Analogues as Human Fatty Acid Synthase Thioesterase Domain Inhibitors: Synthesis and their Cytotoxicity Screening

, 12(6): 495 - 499

Selvaraj Jubie, Pawan Kumar Yadhav, Moola Joghee Nanjan Chandrasekar, Jeyapal Gomathi Priya, Chaitanya MVNL and Palanisamy Dhanabal


DOI: 10.2174/1570180812666141216210751



Synthesis and Anti-tubercular Activity of 6-(4-Chloro/Methyl-phenyl)-4- Arylidene-4,5-dihydropyridazin-3(2H)-one Derivatives Against Mycobacterium tuberculosis

, 12(6): 500 - 504

Mohammad Asif and Anita Singh


DOI: 10.2174/157018081206150507130832



Synthesis, Characterization and Microbial Activity of new Aryl esters of 1,1'-bis(4-hydroxyphenyl)cyclohexane

, 12(6): 505 - 511

Chirag Bhupendra Patel, Bhavin Babu Dhaduk and Parsotam Hari Parsania


DOI: 10.2174/1570180812666141224211602



Preparation and Characterization of CS/(β-CD)/PAA Composite Hydrogels for Controlled Drug Delivery

, 12(6): 512 - 517

Jie Ren, Xiaoci Yang, Mengqi Yao, Jinfen Gu, Xiaohua Tang and W u Yang


DOI: 10.2174/1570180812666150224231250




Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

Biography
View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05

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