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Letters in Drug Design & Discovery

Volume 17, 12 Issues, 2020
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Contents

Letters in Drug Design & Discovery, Volume 12 - Number 4


The Synthesis of Risedronic Acid and Alendronate Applying Phosphorus Oxychloride and Phosphorous Acid in Methanesulfonic Acid

, 12(4): 253 - 258

Alajos Grun, Rita Kovacs, Sandor Garadnay, Istvan Greiner and Gyorgy Keglevich


DOI: 10.2174/1570180811666141010220427



Controlled Release from Solid Pharmaceutical Formulations of two Nalkanoyl- 4-methoxybicyclo[4.2.0]octa-1,3,5-trien-7-ethanamines with Melatoninergic Activity

, 12(4): 259 - 262

Marilena Vlachou, Vasiliki Ioannidou, Maria Vertzoni, Andrew Tsotinis, Pandelis A. Afroudakis and David Sugden


DOI: 10.2174/1570180811666141024005226



Synthesis, Antimicrobial and Pharmacological Evaluation of Thioureaderivatives of 4H-1,2,4-triazole

, 12(4): 263 - 276

Anna Bielenica, Ewa Kedzierska, Sylwia Fidecka, Hanna Maluszynska, Barbara Miroslaw, Anna E. Koziol, Joanna Stefanska, Silvia Madeddu, Gabriele Giliberti, Giuseppina Sanna and Marta Struga


DOI: 10.2174/1570180811666141001010044



First Discovery of Tylophora Alkaloids as HIV Inhibitors

, 12(4): 277 - 283

Ziwen Wang, Mingxiao Wang, Lei Wang, Xue Yao, Yue Li, Juan Tan, Wentao Qiao, Yunqi Geng, Yuxiu Liu and Qingmin Wang


DOI: 10.2174/1570180811666141009235124



Docking Study of Novel Pyrrolidine Derivatives as Potential Dipeptidyl Peptidase-IV (DPP-IV) Inhibitors

, 12(4): 284 - 291

Sant Kumar Verma, Shashi Kant Sharma and Suresh Thareja


DOI: 10.2174/1570180811666141016000752



Identification of Pyrazole Derivative as an Antiviral Agent Against Chikungunya Through HTVS

, 12(4): 292 - 301

Surender Singh Jadav, Barij Nayan Sinha, Boris Pastorino, Xavier de Lamballerie, Rolf Hilgenfeld and Venkatesan Jayaprakash


DOI: 10.2174/1570180811666141001005402



Computer-aided Identification of Novel DprE1 Inhibitors as Potential Anti-TB Lead Compounds: A Hybrid Virtual-screening and Molecular Dynamics Approach

, 12(4): 302 - 313

Yushir Maharaj, Soumendranath Bhakat and Mahmoud E. S. Soliman


DOI: 10.2174/1570180811666141001005536



Synthesis and Biological Activity of Acylthiourea Derivatives Contain 1,2,3-thiadiazole and 1,3,4-thiadiazole

, 12(4): 314 - 318

Ming-Yan Yang, Wen Zhao, Zhao-Hui Sun, Cheng-Xia Tan, Jian-Quan Weng and Xing-Hai Liu


DOI: 10.2174/1570180811666141010000435



Role of Curcumin in Modulating Plasma PON1 Arylesterase Activity and Susceptibility to LDL Oxidation in Oxidatively Challenged Wistar Rats

, 12(4): 319 - 323

Prabhakar Singh and Syed Ibrahim Rizvi


DOI: 10.2174/1570180811666141016000539



The Novel Derivatives of 3-(iminomethyl)-2H-chromen-2-one with Thiourea and Piperazine Structural Motive: Rationale, Synthesis, Antimicrobial and Anti-TB Evaluation

, 12(4): 324 - 341

Harshad P. Lakum, Dhruvin R. Shah and Kishor H. Chikhalia


DOI: 10.2174/1570180811666141009234835




Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

Biography
View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05

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