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Contents

Letters in Drug Design & Discovery, Volume 12 - Number 2


Investigation of New Phenothiazine and Carbazole Derivatives as Potential Inhibitors of Human Farnesyltransferase

, 12(2): 85 - 92

Gina-Mirabela Dumitriu, Alina Ghinet, Dalila Belei, Benoit Rigo, Philippe Gautret, Joelle Dubois and Elena Bicu


DOI: 10.2174/1570180811666140909010435



Quantum-chemical Study on the Thermodynamical Aspect of Competitive Inhibition of Ribonucleotide Reductase by trans-Resveratrol, trans- Piceatannol and Hydroxyurea

, 12(2): 93 - 102

Krzysztof Eder, Damian Mikulski and Marcin Molski


DOI: 10.2174/1570180811666140909005756



Mannich Base Derivatives as the Potential Candidates of Human Topoisomerase II Inhibitors

, 12(2): 103 - 108

Huseyin Istanbullu, Muge Senarisoy, Ercin Erciyas and Zeki Topcu


DOI: 10.2174/1570180811666140901234507



Pd/C-catalyzed Synthesis of (E)-2-arylmethylideneindolin-3-ols Under Ultrasound: Their Initial Evaluation as Potential Anti-proliferative Agents

, 12(2): 109 - 116

Ponugubati Radhakrishna Murthi, Namburi Suresh, Chekuri Sharmila Rani, Mandava Venkata Basaveswara Rao and Manojit Pal


DOI: 10.2174/1570180811666140819224103



Synthesis, in Vitro and in Vivo Anticancer Activity of Hybrids of 3- Hydroxy-indolin-2-one and 2,3-Dihydroquinolin-4(1H)-one

, 12(2): 117 - 123

Lei Zhang, Jing Wang, Wen-Yun Li, Juan Xia, Jing Gao and Qi-Zheng Yao


DOI: 10.2174/1570180811666140909010017



A Divide-and-Conquer Strategy for the Prediction of Protein Contact Map

, 12(2): 124 - 130

Cosme E. Santiesteban-Toca, Gerardo M. Casanola-Martin and Jesus S. Aguilar-Ruiz


DOI: 10.2174/1570180811666140909011206



4-Substituted-2-Methoxyphenol: Suitable Building Block to Prepare New Bioactive Natural-like Hydroxylated Biphenyls

, 12(2): 131 - 139

Maria Antonietta Dettori, Davide Fabbri, Marina Pisano, Carla Rozzo, Giuseppe Palmieri, Alessandro Dessi, Roberto Dallocchio and Giovanna Delogu


DOI: 10.2174/1570180811666140915222343



Alzheimer's Disease Prevention and Use of Traditional Plant Medicines

, 12(2): 140 - 151

Xiaogang Wang, Raphael Dubois and James David Adams Jr


DOI: 10.2174/1570180811666140819223819



Synthesis, Characterization and Microbial Activity of New Bisphenol-C Derivatives

, 12(2): 152 - 157

Bhavin Babu Dhaduk, Chirag Bhupendra Patel and Parsotam Hari Parsania


DOI: 10.2174/1570180811666140915222545



Non-Classical Therapeutic Approach in the Treatment of Alzheimer's Disease: A Mini Review

, 12(2): 158 - 164

Vladan Bajic, Biljana Spremo-Potparevic, Lada Zivkovic, Emina Sudar, Sonja Zafirovic, Milan Obradovic and Esma R. Isenovic


DOI: 10.2174/1570180811666140909010803




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