Contents
Letters in Drug Design & Discovery, Volume 11 - Number 7
In Vitro and In Vivo Investigations into the Carbene Copper Bromide Anticancer Drug Candidate WBC4
, 11(7): 825 - 832Wolfgang Walther, Iduna Fichtner, Frauke Hackenberg, Wojciech Streciwilk and Matthias Tacke
DOI: 10.2174/1570180811666140529004102
In Vitro and In Vivo Investigations into the Carbene Copper Bromide Anticancer Drug Candidate WBC4
Synthesis and Biological Evaluation of New Pyrazole-based Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents
, 11(7): 833 - 839Mehlika Dilek Altıntop, Ahmet Ozdemir, Sinem Ilgın and Ozlem Atli
DOI: 10.2174/1570180811666140226235350
Synthesis and Biological Evaluation of New Pyrazole-based Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents
Synthesis and Anticancer Activity of 2,4,5-triaryl Imidazole Derivatives
, 11(7): 840 - 843Fatemeh Elahian, Morteza Akbari, Maryam Ghasemi, Neda Behtooee, Mohaddeseh Taheri and Mohsen Amini
DOI: 10.2174/1570180811666140313233659
Synthesis and Anticancer Activity of 2,4,5-triaryl Imidazole Derivatives
Detour Cum Distance Matrix Based Topological Descriptors for QSAR/QSPR Part-I: Development and Evaluation
, 11(7): 844 - 863Monika Gupta, Harish Jangra, Prasad V. Bharatam and Anil K. Madan
DOI: 10.2174/1570180811999140605111741
Detour Cum Distance Matrix Based Topological Descriptors for QSAR/QSPR Part-I: Development and Evaluation
Detour Cum Distance Matrix Based Topological Descriptors for QSAR/QSPR Part-II: Application in Drug Discovery Process
, 11(7): 864 - 876Monika Gupta and Anil K. Madan
DOI: 10.2174/1570180811666140401182931
Detour Cum Distance Matrix Based Topological Descriptors for QSAR/QSPR Part-II: Application in Drug Discovery Process
Synthesis and Bioactivity of Novel Carvacrol and Thymol Derivatives Containing 5-Phenyl-2-furan
, 11(7): 877 - 885Zining Cui, Xinghai Li and Yoshihiro Nishida
DOI: 10.2174/1570180811666140220005252
Synthesis and Bioactivity of Novel Carvacrol and Thymol Derivatives Containing 5-Phenyl-2-furan
Investigating the Contributions of Residues to Dipeptidyl Peptidase-IV Inhibitor Binding by Molecular Dynamics Simulation
, 11(7): 886 - 893Mengyuan Liu, Xun Sun and Xian Zhao
DOI: 10.2174/1570180811666140226235522
Investigating the Contributions of Residues to Dipeptidyl Peptidase-IV Inhibitor Binding by Molecular Dynamics Simulation
Identification of Potential MEK1 Inhibitors by Pharmacophore-based Virtual Screening and MD Simulations
, 11(7): 894 - 907Huanhuan Shi, Lu Zhou, Guangkai Bao, Qianying Yi, Suwen Zhou, Yahui Tian and Xiaoli Li
DOI: 10.2174/1570180811666140423221748
Identification of Potential MEK1 Inhibitors by Pharmacophore-based Virtual Screening and MD Simulations
Anionic Linear Globular Dendrimer-G2-Ciprofloxacin Nano-Conjugate: Novel Agent against Wilson Disease Cell Model
, 11(7): 908 - 916Narges Karimi, Mohammad Reza Aghasadeghi, Parichehr Yaghmaei, Hadi Fathi Moghaddam, Nasser Nassiri-Koopaei, Hamid Moloudian, Saleh Najafi, Seyed Ataaollah Shandiz and Mehdi Shafiee Ardestani
DOI: 10.2174/1570180811666140322001829
Anionic Linear Globular Dendrimer-G2-Ciprofloxacin Nano-Conjugate: Novel Agent against Wilson Disease Cell Model
4'-Modified Pyrimidine Nucleosides as Potential Anti-hepatitis C Virus (HCV) Agents
, 11(7): 917 - 921Neeraj Shakya, Satish Vedi, Chao Liang, Babita Agrawal and Rakesh Kumar
DOI: 10.2174/1570180811666140401184856
4'-Modified Pyrimidine Nucleosides as Potential Anti-hepatitis C Virus (HCV) Agents
Preparation of Supramolecular Hydrogels Containing Poloxamers and Methyl-β -cyclodextrin
, 11(7): 922 - 929Maria Joao Garcia, Joana Ruivo, Rita Oliveira and Ana Figueiras
DOI: 10.2174/1570180811666140220005117
Preparation of Supramolecular Hydrogels Containing Poloxamers and Methyl-β -cyclodextrin
Synthesis of Novel and Highly Functionalized Pyrimidine-5-carboxylate Derivatives and their Antimicrobial Evaluation
, 11(7): 930 - 936Hardik B. Ghodasara, Rajesh G. Vaghasiya, Bharat G. Patel and Viresh H. Shah
DOI: 10.2174/1570180811666140401182419
Synthesis of Novel and Highly Functionalized Pyrimidine-5-carboxylate Derivatives and their Antimicrobial Evaluation
In Vivo Assessment of Antileishmanial Property of 4-(4,4,8-Trimethyl-7- oxo-3-oxabicyclo[3.3.1]non-2-yl)-benzoic Acid Methyl Ester, an Oxabicyclo[ 3.3.1]nonanones
, 11(7): 937 - 939Prakash Saudagar, Shyam Lal Mudavath, Pipas Saha, Anil K. Saikia, Shyam Sundar and Vikash Kumar Dubey
DOI: 10.2174/1570180811666140423203826
In Vivo Assessment of Antileishmanial Property of 4-(4,4,8-Trimethyl-7- oxo-3-oxabicyclo[3.3.1]non-2-yl)-benzoic Acid Methyl Ester, an Oxabicyclo[ 3.3.1]nonanones
Synthesis and Antifungal Activity of 1,2,3-thiadiazole Derivatives Containing 1,3,4-thiadiazole Moiety
, 11(7): 940 - 943Shui-Lin Yan, Ming-Yan Yang, Zhao-Hui Sun, Li-Jing Min, Cheng-Xia Tan, Jian-Quan Weng, Hong-Ke Wu and Xing-Hai Liu
DOI: 10.2174/1570180811666140423222141
Synthesis and Antifungal Activity of 1,2,3-thiadiazole Derivatives Containing 1,3,4-thiadiazole Moiety
In Vitro Screening of Some Heterocyclic Compounds Against Human ABHD6 and ABHD12 Hydrolases
, 11(7): 944 - 952Agnieszka A. Kaczor, Antti Poso and Monika Pitucha
DOI: 10.2174/1570180811666140313233940
In Vitro Screening of Some Heterocyclic Compounds Against Human ABHD6 and ABHD12 Hydrolases
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