Letters in Drug Design & Discovery
Volume 18, 12 Issues, 2021
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
Contents
Letters in Drug Design & Discovery, Volume 11 - Number 7
In Vitro and In Vivo Investigations into the Carbene Copper Bromide Anticancer Drug Candidate WBC4
, 11(7): 825 - 832Wolfgang Walther, Iduna Fichtner, Frauke Hackenberg, Wojciech Streciwilk and Matthias Tacke
DOI: 10.2174/1570180811666140529004102
In Vitro and In Vivo Investigations into the Carbene Copper Bromide Anticancer Drug Candidate WBC4
Synthesis and Biological Evaluation of New Pyrazole-based Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents
, 11(7): 833 - 839Mehlika Dilek Altıntop, Ahmet Ozdemir, Sinem Ilgın and Ozlem Atli
DOI: 10.2174/1570180811666140226235350
Synthesis and Biological Evaluation of New Pyrazole-based Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents
Synthesis and Anticancer Activity of 2,4,5-triaryl Imidazole Derivatives
, 11(7): 840 - 843Fatemeh Elahian, Morteza Akbari, Maryam Ghasemi, Neda Behtooee, Mohaddeseh Taheri and Mohsen Amini
DOI: 10.2174/1570180811666140313233659
Synthesis and Anticancer Activity of 2,4,5-triaryl Imidazole Derivatives
Detour Cum Distance Matrix Based Topological Descriptors for QSAR/QSPR Part-I: Development and Evaluation
, 11(7): 844 - 863Monika Gupta, Harish Jangra, Prasad V. Bharatam and Anil K. Madan
DOI: 10.2174/1570180811999140605111741
Detour Cum Distance Matrix Based Topological Descriptors for QSAR/QSPR Part-I: Development and Evaluation
Detour Cum Distance Matrix Based Topological Descriptors for QSAR/QSPR Part-II: Application in Drug Discovery Process
, 11(7): 864 - 876Monika Gupta and Anil K. Madan
DOI: 10.2174/1570180811666140401182931
Detour Cum Distance Matrix Based Topological Descriptors for QSAR/QSPR Part-II: Application in Drug Discovery Process
Synthesis and Bioactivity of Novel Carvacrol and Thymol Derivatives Containing 5-Phenyl-2-furan
, 11(7): 877 - 885Zining Cui, Xinghai Li and Yoshihiro Nishida
DOI: 10.2174/1570180811666140220005252
Synthesis and Bioactivity of Novel Carvacrol and Thymol Derivatives Containing 5-Phenyl-2-furan
Investigating the Contributions of Residues to Dipeptidyl Peptidase-IV Inhibitor Binding by Molecular Dynamics Simulation
, 11(7): 886 - 893Mengyuan Liu, Xun Sun and Xian Zhao
DOI: 10.2174/1570180811666140226235522
Investigating the Contributions of Residues to Dipeptidyl Peptidase-IV Inhibitor Binding by Molecular Dynamics Simulation
Identification of Potential MEK1 Inhibitors by Pharmacophore-based Virtual Screening and MD Simulations
, 11(7): 894 - 907Huanhuan Shi, Lu Zhou, Guangkai Bao, Qianying Yi, Suwen Zhou, Yahui Tian and Xiaoli Li
DOI: 10.2174/1570180811666140423221748
Identification of Potential MEK1 Inhibitors by Pharmacophore-based Virtual Screening and MD Simulations
Anionic Linear Globular Dendrimer-G2-Ciprofloxacin Nano-Conjugate: Novel Agent against Wilson Disease Cell Model
, 11(7): 908 - 916Narges Karimi, Mohammad Reza Aghasadeghi, Parichehr Yaghmaei, Hadi Fathi Moghaddam, Nasser Nassiri-Koopaei, Hamid Moloudian, Saleh Najafi, Seyed Ataaollah Shandiz and Mehdi Shafiee Ardestani
DOI: 10.2174/1570180811666140322001829
Anionic Linear Globular Dendrimer-G2-Ciprofloxacin Nano-Conjugate: Novel Agent against Wilson Disease Cell Model
4'-Modified Pyrimidine Nucleosides as Potential Anti-hepatitis C Virus (HCV) Agents
, 11(7): 917 - 921Neeraj Shakya, Satish Vedi, Chao Liang, Babita Agrawal and Rakesh Kumar
DOI: 10.2174/1570180811666140401184856
4'-Modified Pyrimidine Nucleosides as Potential Anti-hepatitis C Virus (HCV) Agents
Preparation of Supramolecular Hydrogels Containing Poloxamers and Methyl-β -cyclodextrin
, 11(7): 922 - 929Maria Joao Garcia, Joana Ruivo, Rita Oliveira and Ana Figueiras
DOI: 10.2174/1570180811666140220005117
Preparation of Supramolecular Hydrogels Containing Poloxamers and Methyl-β -cyclodextrin
Synthesis of Novel and Highly Functionalized Pyrimidine-5-carboxylate Derivatives and their Antimicrobial Evaluation
, 11(7): 930 - 936Hardik B. Ghodasara, Rajesh G. Vaghasiya, Bharat G. Patel and Viresh H. Shah
DOI: 10.2174/1570180811666140401182419
Synthesis of Novel and Highly Functionalized Pyrimidine-5-carboxylate Derivatives and their Antimicrobial Evaluation
In Vivo Assessment of Antileishmanial Property of 4-(4,4,8-Trimethyl-7- oxo-3-oxabicyclo[3.3.1]non-2-yl)-benzoic Acid Methyl Ester, an Oxabicyclo[ 3.3.1]nonanones
, 11(7): 937 - 939Prakash Saudagar, Shyam Lal Mudavath, Pipas Saha, Anil K. Saikia, Shyam Sundar and Vikash Kumar Dubey
DOI: 10.2174/1570180811666140423203826
In Vivo Assessment of Antileishmanial Property of 4-(4,4,8-Trimethyl-7- oxo-3-oxabicyclo[3.3.1]non-2-yl)-benzoic Acid Methyl Ester, an Oxabicyclo[ 3.3.1]nonanones
Synthesis and Antifungal Activity of 1,2,3-thiadiazole Derivatives Containing 1,3,4-thiadiazole Moiety
, 11(7): 940 - 943Shui-Lin Yan, Ming-Yan Yang, Zhao-Hui Sun, Li-Jing Min, Cheng-Xia Tan, Jian-Quan Weng, Hong-Ke Wu and Xing-Hai Liu
DOI: 10.2174/1570180811666140423222141
Synthesis and Antifungal Activity of 1,2,3-thiadiazole Derivatives Containing 1,3,4-thiadiazole Moiety
In Vitro Screening of Some Heterocyclic Compounds Against Human ABHD6 and ABHD12 Hydrolases
, 11(7): 944 - 952Agnieszka A. Kaczor, Antti Poso and Monika Pitucha
DOI: 10.2174/1570180811666140313233940
In Vitro Screening of Some Heterocyclic Compounds Against Human ABHD6 and ABHD12 Hydrolases
Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)
Biography
University of Hradec Kralove
Hradec Kralove
Biography
Biography of K. Kuca
Kamil Kuca is working for several academic institutes (University of Hradec Kralove, Czech Republic; University Hospital Hradec Kralove, Czech republic; Florida International University, USA; Yangtze University, China; etc.). He is recently rector of the University of Hradec Kralove. He was also technology scout focused on biomedicine in the past. His research interests are toxicology, pharmacology, drug design, technology transfer, pharmacoeconomy, chemical and biological terrorism, etc. He was/is principal investigator on numerous national and international projects (EU, NATO, GACR, IGA MZ, MSMT etc.). He has published more than 350 IF research papers. He is working with several companies as a scientific consultant. He has lots of cooperators throughout the world (e.g. Korea, Croatia, United Arab Emirates, USA, France, Turkey, China, Singapore, Sweden, and Brazil). His Hindex is 36, number of citation in WoS is over 3000.
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Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
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