Contents

Letters in Drug Design & Discovery, Volume 11 - Number 7

In Vitro and In Vivo Investigations into the Carbene Copper Bromide Anticancer Drug Candidate WBC4

, 11(7): 825 - 832

Wolfgang Walther, Iduna Fichtner, Frauke Hackenberg, Wojciech Streciwilk and Matthias Tacke


DOI: 10.2174/1570180811666140529004102





Synthesis and Biological Evaluation of New Pyrazole-based Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents

, 11(7): 833 - 839

Mehlika Dilek Altıntop, Ahmet Ozdemir, Sinem Ilgın and Ozlem Atli


DOI: 10.2174/1570180811666140226235350





Synthesis and Anticancer Activity of 2,4,5-triaryl Imidazole Derivatives

, 11(7): 840 - 843

Fatemeh Elahian, Morteza Akbari, Maryam Ghasemi, Neda Behtooee, Mohaddeseh Taheri and Mohsen Amini


DOI: 10.2174/1570180811666140313233659





Detour Cum Distance Matrix Based Topological Descriptors for QSAR/QSPR Part-I: Development and Evaluation

, 11(7): 844 - 863

Monika Gupta, Harish Jangra, Prasad V. Bharatam and Anil K. Madan


DOI: 10.2174/1570180811999140605111741





Detour Cum Distance Matrix Based Topological Descriptors for QSAR/QSPR Part-II: Application in Drug Discovery Process

, 11(7): 864 - 876

Monika Gupta and Anil K. Madan


DOI: 10.2174/1570180811666140401182931





Synthesis and Bioactivity of Novel Carvacrol and Thymol Derivatives Containing 5-Phenyl-2-furan

, 11(7): 877 - 885

Zining Cui, Xinghai Li and Yoshihiro Nishida


DOI: 10.2174/1570180811666140220005252





Investigating the Contributions of Residues to Dipeptidyl Peptidase-IV Inhibitor Binding by Molecular Dynamics Simulation

, 11(7): 886 - 893

Mengyuan Liu, Xun Sun and Xian Zhao


DOI: 10.2174/1570180811666140226235522





Identification of Potential MEK1 Inhibitors by Pharmacophore-based Virtual Screening and MD Simulations

, 11(7): 894 - 907

Huanhuan Shi, Lu Zhou, Guangkai Bao, Qianying Yi, Suwen Zhou, Yahui Tian and Xiaoli Li


DOI: 10.2174/1570180811666140423221748





Anionic Linear Globular Dendrimer-G2-Ciprofloxacin Nano-Conjugate: Novel Agent against Wilson Disease Cell Model

, 11(7): 908 - 916

Narges Karimi, Mohammad Reza Aghasadeghi, Parichehr Yaghmaei, Hadi Fathi Moghaddam, Nasser Nassiri-Koopaei, Hamid Moloudian, Saleh Najafi, Seyed Ataaollah Shandiz and Mehdi Shafiee Ardestani


DOI: 10.2174/1570180811666140322001829





4'-Modified Pyrimidine Nucleosides as Potential Anti-hepatitis C Virus (HCV) Agents

, 11(7): 917 - 921

Neeraj Shakya, Satish Vedi, Chao Liang, Babita Agrawal and Rakesh Kumar


DOI: 10.2174/1570180811666140401184856





Preparation of Supramolecular Hydrogels Containing Poloxamers and Methyl-β -cyclodextrin

, 11(7): 922 - 929

Maria Joao Garcia, Joana Ruivo, Rita Oliveira and Ana Figueiras


DOI: 10.2174/1570180811666140220005117





Synthesis of Novel and Highly Functionalized Pyrimidine-5-carboxylate Derivatives and their Antimicrobial Evaluation

, 11(7): 930 - 936

Hardik B. Ghodasara, Rajesh G. Vaghasiya, Bharat G. Patel and Viresh H. Shah


DOI: 10.2174/1570180811666140401182419





In Vivo Assessment of Antileishmanial Property of 4-(4,4,8-Trimethyl-7- oxo-3-oxabicyclo[3.3.1]non-2-yl)-benzoic Acid Methyl Ester, an Oxabicyclo[ 3.3.1]nonanones

, 11(7): 937 - 939

Prakash Saudagar, Shyam Lal Mudavath, Pipas Saha, Anil K. Saikia, Shyam Sundar and Vikash Kumar Dubey


DOI: 10.2174/1570180811666140423203826





Synthesis and Antifungal Activity of 1,2,3-thiadiazole Derivatives Containing 1,3,4-thiadiazole Moiety

, 11(7): 940 - 943

Shui-Lin Yan, Ming-Yan Yang, Zhao-Hui Sun, Li-Jing Min, Cheng-Xia Tan, Jian-Quan Weng, Hong-Ke Wu and Xing-Hai Liu


DOI: 10.2174/1570180811666140423222141





In Vitro Screening of Some Heterocyclic Compounds Against Human ABHD6 and ABHD12 Hydrolases

, 11(7): 944 - 952

Agnieszka A. Kaczor, Antti Poso and Monika Pitucha


DOI: 10.2174/1570180811666140313233940





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