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Letters in Drug Design & Discovery

Volume 18, 12 Issues, 2021
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research


Letters in Drug Design & Discovery, Volume 11 - Number 7

In Vitro and In Vivo Investigations into the Carbene Copper Bromide Anticancer Drug Candidate WBC4

, 11(7): 825 - 832

Wolfgang Walther, Iduna Fichtner, Frauke Hackenberg, Wojciech Streciwilk and Matthias Tacke

DOI: 10.2174/1570180811666140529004102

Synthesis and Biological Evaluation of New Pyrazole-based Thiazolyl Hydrazone Derivatives as Potential Anticancer Agents

, 11(7): 833 - 839

Mehlika Dilek Altıntop, Ahmet Ozdemir, Sinem Ilgın and Ozlem Atli

DOI: 10.2174/1570180811666140226235350

Synthesis and Anticancer Activity of 2,4,5-triaryl Imidazole Derivatives

, 11(7): 840 - 843

Fatemeh Elahian, Morteza Akbari, Maryam Ghasemi, Neda Behtooee, Mohaddeseh Taheri and Mohsen Amini

DOI: 10.2174/1570180811666140313233659

Detour Cum Distance Matrix Based Topological Descriptors for QSAR/QSPR Part-I: Development and Evaluation

, 11(7): 844 - 863

Monika Gupta, Harish Jangra, Prasad V. Bharatam and Anil K. Madan

DOI: 10.2174/1570180811999140605111741

Detour Cum Distance Matrix Based Topological Descriptors for QSAR/QSPR Part-II: Application in Drug Discovery Process

, 11(7): 864 - 876

Monika Gupta and Anil K. Madan

DOI: 10.2174/1570180811666140401182931

Synthesis and Bioactivity of Novel Carvacrol and Thymol Derivatives Containing 5-Phenyl-2-furan

, 11(7): 877 - 885

Zining Cui, Xinghai Li and Yoshihiro Nishida

DOI: 10.2174/1570180811666140220005252

Investigating the Contributions of Residues to Dipeptidyl Peptidase-IV Inhibitor Binding by Molecular Dynamics Simulation

, 11(7): 886 - 893

Mengyuan Liu, Xun Sun and Xian Zhao

DOI: 10.2174/1570180811666140226235522

Identification of Potential MEK1 Inhibitors by Pharmacophore-based Virtual Screening and MD Simulations

, 11(7): 894 - 907

Huanhuan Shi, Lu Zhou, Guangkai Bao, Qianying Yi, Suwen Zhou, Yahui Tian and Xiaoli Li

DOI: 10.2174/1570180811666140423221748

Anionic Linear Globular Dendrimer-G2-Ciprofloxacin Nano-Conjugate: Novel Agent against Wilson Disease Cell Model

, 11(7): 908 - 916

Narges Karimi, Mohammad Reza Aghasadeghi, Parichehr Yaghmaei, Hadi Fathi Moghaddam, Nasser Nassiri-Koopaei, Hamid Moloudian, Saleh Najafi, Seyed Ataaollah Shandiz and Mehdi Shafiee Ardestani

DOI: 10.2174/1570180811666140322001829

4'-Modified Pyrimidine Nucleosides as Potential Anti-hepatitis C Virus (HCV) Agents

, 11(7): 917 - 921

Neeraj Shakya, Satish Vedi, Chao Liang, Babita Agrawal and Rakesh Kumar

DOI: 10.2174/1570180811666140401184856

Preparation of Supramolecular Hydrogels Containing Poloxamers and Methyl-β -cyclodextrin

, 11(7): 922 - 929

Maria Joao Garcia, Joana Ruivo, Rita Oliveira and Ana Figueiras

DOI: 10.2174/1570180811666140220005117

Synthesis of Novel and Highly Functionalized Pyrimidine-5-carboxylate Derivatives and their Antimicrobial Evaluation

, 11(7): 930 - 936

Hardik B. Ghodasara, Rajesh G. Vaghasiya, Bharat G. Patel and Viresh H. Shah

DOI: 10.2174/1570180811666140401182419

In Vivo Assessment of Antileishmanial Property of 4-(4,4,8-Trimethyl-7- oxo-3-oxabicyclo[3.3.1]non-2-yl)-benzoic Acid Methyl Ester, an Oxabicyclo[ 3.3.1]nonanones

, 11(7): 937 - 939

Prakash Saudagar, Shyam Lal Mudavath, Pipas Saha, Anil K. Saikia, Shyam Sundar and Vikash Kumar Dubey

DOI: 10.2174/1570180811666140423203826

Synthesis and Antifungal Activity of 1,2,3-thiadiazole Derivatives Containing 1,3,4-thiadiazole Moiety

, 11(7): 940 - 943

Shui-Lin Yan, Ming-Yan Yang, Zhao-Hui Sun, Li-Jing Min, Cheng-Xia Tan, Jian-Quan Weng, Hong-Ke Wu and Xing-Hai Liu

DOI: 10.2174/1570180811666140423222141

In Vitro Screening of Some Heterocyclic Compounds Against Human ABHD6 and ABHD12 Hydrolases

, 11(7): 944 - 952

Agnieszka A. Kaczor, Antti Poso and Monika Pitucha

DOI: 10.2174/1570180811666140313233940


K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)
View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05

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