Letters in Drug Design & Discovery
Volume 18, 12 Issues, 2021
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
Contents
Letters in Drug Design & Discovery, Volume 11 - Number 5
Graphical Abstract
Synthesis of Oxygenated Chalcones with Anti-Staphylococcal Activity
, 11(5): 525 - 530Luciana Dalla-Vechia, Cíntia Janine Kiekow, Ivana Correa Ramos Leal, Katia Regina Netto Dos Santos, Simone Cristina Baggio Gnoatto, Hugo Verli, Rodrigo Octavio Mendonca Alves de Souza and Grace Gosmann
DOI: 10.2174/1570180810666131125221032
Designing New 5-Nitroimidazoles: Towards Safer Anti-infectious Agents
, 11(5): 531 - 559Maxime D. Crozet, Thierry Terme and Patrice Vanelle
DOI: 10.2174/1570180810666131122010615
Novel Urea/Thiourea Derivatives of Quinazolin-4(3H)-one: Design, Synthesis, Antimicrobial and Anti-TB Study
, 11(5): 560 - 571Dhruvin R. Shah, Rahul P. Modh, Dhara V. Desai and Kishor H. Chikhalia
DOI: 10.2174/1570180810666131122003517
Novel 4-bromo-2-(3-methyl-1-(substituted-phenylsulfonyl)-4,5-dihydro-1- H-pyrazol-5-yl)phenol Derivatives: Synthesis and Antibacterial Activity
, 11(5): 572 - 577Qing Chenga, Ying-Ming Jia, Fei-Hu Cheng and Xin-Hua Liu
DOI: 10.2174/1570180810666131122234935
Synthesis and Anticancer Activity of Some 2-[3/4-(2-Substituted Phenyl-2- oxoethoxy)benzylidene]-6-substituted-2,3-dihydro-1H-inden-1-one Derivatives
, 11(5): 578 - 585Nalan Gundogdu-Karaburun, Ahmet Cagri Karaburun, Seref Demirayak, Ismail Kayagil and Leyla Yurttas
DOI: 10.2174/1570180811666140403001212
Synthesis and Antitumor Activities of α-,γ-mangostin Derivatives
, 11(5): 586 - 593Kai Cheng, Gui-lin Zhang, Sheng-xiang Qiu, Yan-qing Liu, Yan-fei Wang, Song Liu, Yan Shan, Bo Yu and Yu Lu
DOI: 10.2174/1570180811666131217003216
A Facile Synthesis and Anticancer Activity Evaluation of Spiro Analogues of Benzothiazolylchromeno/pyrano Derivatives
, 11(5): 594 - 600Anand Kumar Arya, Kulbhushan Rana and Mahendra Kumar
DOI: 10.2174/1570180811666131210000903
Design, Synthesis and In-Vitro Evaluation of Polymer-linked Prodrug of Methotrexate for the Targeted Delivery to the Colon
, 11(5): 601 - 610Nishu Singla, Rajiv Sharma and T.R. Bhardwaj
DOI: 10.2174/1570180811666131217002719
Potent Neuroprotective Activity of Monoterpene Derived 4-[(3aR,7aS)- 1,3,3a,4,5,7a-Hexahydro-3,3,6-trimethylisobenzofuran-1-yl]-2-methoxyphenol in MPTP Mice Model
, 11(5): 611 - 617Alla V. Pavlova, Irina V. Il'ina, Ekaterina A. Morozova, Dina V. Korchagina, Svetlana Yu. Kurbakova, Irina V. Sorokina, Tatyana G. Tolstikova, Konstantin P. Volcho and Nariman F. Salakhutdinov
DOI: 10.2174/1570180811666131210000316
QSAR Study on Diketo Acid and Carboxamide Derivatives as Potent HIV- 1 Integrase Inhibitor
, 11(5): 618 - 627Arodola Olayide Adebimpe, Radha Charan Dash and Mahmoud E. S. Soliman
DOI: 10.2174/1570180811666131217003010
Synthesis and Anticonvulsant Activity Evaluation of 4-butyl-5-(4- alkoxyphenyl)-2H-1,2,4-triazole-3(4H)-ones
, 11(5): 628 - 635Zi-Shi Zhu, Shi-Ben Wang, Xian-Qing Deng, Da-Chuan Liu and Zhe-Shan Quan
DOI: 10.2174/1570180810666131122003939
Artificial Neural Networks Modeling of Release of Olanzapine From Glycerol Monooleate Matrices
, 11(5): 636 - 648G. Bagheri, E. Vasheghani-Farahani, M. Ardjmand, H. Attar and F. A. Dorkoosh
DOI: 10.2174/1570180811666131227193958
4D-QSAR Model for Compounds with Binding Affinity Towards Dopamine D2 Receptors
, 11(5): 649 - 664Daniela Rodrigues Silva, Teodorico C. Ramalho and Elaine F. F. da Cunha
DOI: 10.2174/1570180810666131113213448
A Combined DFT and QSAR Calculations to Study Substituted Biphenyl imidazoles as Bombesin Receptor Subtype-3 Agonists
, 11(5): 665 - 676Mohsen Shahlaei, Amin Nowroozi and Reza Khodarahmi
DOI: 10.2174/1570180811666131203002858
Synthesis and In Vivo Hepatoprotective Activity of Some Novel Andrographolide Derivatives
, 11(5): 677 - 685Chunlei Tang, Guolong Gu, Baowei Yang, Xuekun Wang, Hai Qian, Wenlong Huang, Xiaoyun Zhu and Jing Li
DOI: 10.2174/1570180810666131123002409
Development of Pyrazole Compounds as Antidiabetic Agent: A Review
, 11(5): 686 - 703Prasanna A. Datar and Sonali R. Jadhav
DOI: 10.2174/1570180810666131113212354
Editor-in-Chief
K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)
Biography
University of Hradec Kralove
Hradec Kralove
Biography
Biography of K. Kuca
Kamil Kuca is working for several academic institutes (University of Hradec Kralove, Czech Republic; University Hospital Hradec Kralove, Czech republic; Florida International University, USA; Yangtze University, China; etc.). He is recently rector of the University of Hradec Kralove. He was also technology scout focused on biomedicine in the past. His research interests are toxicology, pharmacology, drug design, technology transfer, pharmacoeconomy, chemical and biological terrorism, etc. He was/is principal investigator on numerous national and international projects (EU, NATO, GACR, IGA MZ, MSMT etc.). He has published more than 350 IF research papers. He is working with several companies as a scientific consultant. He has lots of cooperators throughout the world (e.g. Korea, Croatia, United Arab Emirates, USA, France, Turkey, China, Singapore, Sweden, and Brazil). His Hindex is 36, number of citation in WoS is over 3000.
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Journal History
Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
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