Contents

Letters in Drug Design & Discovery, Volume 11 - Number 4

Graphical Abstracts

, 11(4): i - vii


DOI: 10.2174/157018081104140311111852




In Vitro Antitumoral Activity of Palladium(II) and Platinum(II) Complexes with O,O'-Dialkyl Esters of Ethylene-bis(S)-Leucine

, 11(4): 387 - 394

Jelena M. Vujic, Goran N. Kaluderovic, Tatjana P. Stanojkovic, Jadranka A. Antic and Srecko R. Trifunovic


DOI: 10.2174/15701808113106660092





Synthesis and Antitumor Invasive Activity of Novel Ionone Alkaloid Derivatives

, 11(4): 395 - 402

Hai-Jun Fang, Qian Liu, Chun-Chun Gan, Mei-Na Jin, Nan Qin and Hong-Quan Duan


DOI: 10.2174/15701808113106660094





Toward the Identification of Novel Carbonic Anhydrase XIV Inhibitors using 3D-QSAR Pharmacophore Model, Virtual Screening and Molecular Docking Study

, 11(4): 403 - 412

Tao Liu, Lu Zhou, Taijin Wang, Lufen He and Xiangyang Tang


DOI: 10.2174/15701808113106660083





Synthesis of 2,5-Disubstituted-1,3,4-oxadiazole Analogs as Novel Anticancer and Antimicrobial Agents

, 11(4): 413 - 419

Mohamed Jawed Ahsan, Jyotika Sharma, Sandeep Bhatia, Pramod Kumar Goyal, Kailash Shankhala and Mukand Didel


DOI: 10.2174/1570180810666131113211647





QSAR Study of H1N1 Neuraminidase Inhibitors from Influenza a Virus

, 11(4): 420 - 427

Apilak Worachartcheewan, Chanin Nantasenamat, Chartchalerm Isarankura-Na-Ayudhya and Virapong Prachayasittikul


DOI: 10.2174/15701808113106660085





In-Vitro Antiproliferative Activity of New Tetrahydroisoquinolines (THIQs) on Ishikawa Cells and their 3D Pharmacophore Models

, 11(4): 428 - 436

Suresh Kumar V. K. Eyunni, Madhavi Gangapuram and Kinfe K. Redda


DOI: 10.2174/1570180811666131203002502





Synthesis, In Vitro Activity and Rationalisation of a Series of Dialkyl Esters of 5-Aminosulfonylisophthanoate as Potential Estrone Sulfatase (ES) Inhibitors

, 11(4): 437 - 443

Sabbir Ahmed and Chirag K. Patel


DOI: 10.2174/15701808113106660081





Design and Synthesis of Novel 2- Substituted Benzothiazole Compounds as PTP1B Inhibitors

, 11(4): 444 - 453

Arun P. Chandrasekharappa, Sangamesh E. Badiger, Pramod K. Dubey, Sunil K. Panigrahi and Sekhar Reddy VVV. Manukonda


DOI: 10.2174/15701808113106660076





Diverse Models for the Prediction of Dual mTOR and PI3Kα Inhibitory Activities of Substituted 4-morpholinopyrrolopyrimidines

, 11(4): 454 - 473

Monika Gupta and A. K. Madan


DOI: 10.2174/15701808113106660089





Synthesis, Molecular Docking and In Vitro Antimicrobial Studies of Novel Pyrazole Analogues of Curcumin

, 11(4): 474 - 483

Dileep Kumar, Harish B. G., Mayank Gangwar, Manish Kumar, Dharmendra Kumar, Ragini Tilak, Gopal Nath, Ashok Kumar and Sushil Kumar Singh


DOI: 10.2174/15701808113106660087





Improved Synthesis of Antiviral Drug Valacyclovir Hydrochloride

, 11(4): 484 - 487

Keshava Navin Kumar Reddy, Murugulla Adharvana Chari, Mayur. D. Khunt, B. Ramachandra Reddy, Vurimidi Himabindu and Ghanta Mahesh Reddy


DOI: 10.2174/15701808113106660090





Synthesis and Evaluation of Anticonvulsant Activities of Triazole- Incorporated Benzothiazoles

, 11(4): 488 - 494

Ming-Xia Song, Hong Zeng, Xian-Qing Deng and Zhe-Shan Quan


DOI: 10.2174/15701808113106660093





Improvement of Generic Sevoflurane by a New Production Process

, 11(4): 495 - 501

Tomo Hayase, Shigekazu Sugino, Shun-suke Tachibana, Naoyuki Hirata and Michiaki Yamakage


DOI: 10.2174/1570180810666131113211447





The Study of the Biological Activity of Amino-Substituted Benzofuroxans

, 11(4): 502 - 512

Elena A. Chugunova, Alexandra D. Voloshina, Rezeda E. Mukhamatdinova, Igor V. Serkov, Alexey N. Proshin, Elmira M. Gibadullina, Alexander R. Burilov, Natalia V. Kulik, Vladimir V. Zobov, Dmitry B. Krivolapov, Alexey B. Dobrynin and Regis Goumont


DOI: 10.2174/1570180810666131122010403





Computer-Aided Perspective for the Design of Flexible HIV Non- Nucleoside Reverse Transcriptase Inhibitors (NNRTIs): de-novo Drug Design, Virtual Screening and Molecular Dynamics Simulations

, 11(4): 513 - 524

Suri Moonsamy and Mahmoud E. S. Soliman


DOI: 10.2174/15701808113109990048





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