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Letters in Drug Design & Discovery, Volume 11 - Number 2


Synthesis of 1-aroyl-3,5-dimethyl-1H-pyrazoles as Anti-HCV and Anticancer Agents

, 11(2): 121 - 131

Sevil Aydın, Neerja Kaushik-Basu, Suna Özbaş-Turan, Jülide Akbuğa, Pınar Mega Tiber, Oya Orun, K. R. Gurukumar, Amartya Basu and Ş. Güniz Küçükgüzel


DOI: 10.2174/15701808113109990069



Synthesis of Unsymmetrical C5-Curcuminoids as Potential Anticancer Agents

, 11(2): 138 - 149

Sunny Manohar, Anuj Thakur, Shabana I. Khan, Guojing Sun, Nanting Ni, Binghe Wang and Diwan S. Rawat


DOI: 10.2174/15701808113109990061



Synthesis of Highly Functionalised Dispiropyrrolidine Derivatives as Novel Acetylcholinesterase Inhibitors

, 11(2): 156 - 161

Ang Chee Wei, Mohamed Ashraf Ali, Yeong Keng Yoon, Rusli Ismail, Tan Soo Choon, Kooi-Yeong Khaw, Vikneswaran Murugaiyah and Venu Sanjeevi Lakshmipathi


DOI: 10.2174/15701808113109990038



Antidepressant Activity of 8-(trifluoromethyl)-1,2,3,4,5-benzopentathiepin- 6-amine hydrochloride (TC-2153): Comparison with Classical Antidepressants

, 11(2): 169 - 173

Alexander V. Kulikov, Maria A. Tikhonova, Elizabeth A. Kulikova, Konstantin P. Volcho, Tatyana M. Khomenko, Nariman F. Salakhutdinov and Nina K. Popova


DOI: 10.2174/15701808113106660079




Cu-mediated synthesis of 2,3-dihydro-1H-pyrrolo[3,2,1-ij]quinolin-1-ones as potential inhibitors of sirtuins

, 11(2): 199 - 206

Sreerama Srinivas Rao, Dandela Rambabu, Mohosin Layek, Kummari Lalith Kumar, Mandava Venkata Basaveswara Rao, Devyani Haldar and Manojit Pal


DOI: 10.2174/15701808113109990065



Molecular Modeling and Ligand-Protein Interaction of N-Protein of Chandipura Virus

, 11(2): 211 - 221

Ganesh Chandra Sahoo, Md. Yousuf Ansari, Sindhuprava Rana, Manas Ranjan Dikhit, Roshan Kamal Topno, Krishna Pandey and Pradeep Das


DOI: 10.2174/15701808113109990070


Synthesis of Novel and Highly Functionalized 4-hydroxycoumarin Chalcone and their Pyrazoline Derivatives as Anti-Tuberculosis Agents

, 11(2): 222 - 230

Mohammad Asad, Farzana Beevi, Suresh Pandian Ganesan, Chuan-Wei Oo, Raju Suresh Kumar, Venu Laxmipathi, Hasnah Osman and Mohamed Ashraf Ali


DOI: 10.2174/15701808113109990055


Interaction between Basic 7S Globulin and Leginsulin in Soybean [Glycine max]: A Structural Insight

, 11(2): 231 - 239

Amandeep Singh, Prasoon Kumar Thakur, Megha Meena, Dhiraj Kumar, Sonika Bhatnagar, Ashok K. Dubey and Md. Imtaiyaz Hassan


DOI: 10.2174/15701808113109990060


Biochemical Changes Evidenced in Alzheimer's Disease: A Mini-Review

, 11(2): 240 - 248

Luciana Scotti, Francisco Jaime Bezerra Mendonça Junior, Marcelo Sobral da Silva, Ivan R. Pitta and Marcus Tullius Scotti


DOI: 10.2174/15701808113109990063



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