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Letters in Drug Design & Discovery

Volume 18, 12 Issues, 2021
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access


Letters in Drug Design & Discovery, Volume 11 - Number 10

Synthesis of Salicylic Acid-based 1,3,4-oxadiazole Derivatives Coupled with Chiral Oxazolidinones: Novel Hybrid Heterocycles as Antitumor Agents

, 11(10): 1133 - 1142

M. S. R. Murty, Raju Penthala, Lekshmi R. Nath and Ruby John Anto

DOI: 10.2174/1570180811666140627004607

Synthesis and Cholinesterase Inhibition Activity of New Pyrrolopyrimidine Derivatives

, 11(10): 1143 - 1148

Rangaswamy Roopashree, Toreshettahally Ramesh Swaroop, Swamy Jagadish, Chakrabhavi Dhananjaya Mohan and Kanchugarakoppal Subbegowda Rangappa

DOI: 10.2174/1570180811666140704171902

Design, Synthesis and in vitro Cytotoxicity Evaluation of New 3',4'-bis (3,4,5-trisubstituted)-4'H-spiro[indene-2,5'-isoxazol]-1(3H)-one Derivatives as Promising Anticancer Agents

, 11(10): 1149 - 1161

Hoda Abolhasani, Afshin Zarghi, Ahmad Abolhasani, Maryam Hamzeh-Mivehroud, Nasrin Bargahi, Behrouz Notash, Javid Shahbazi Mojarrad and Siavoush Dastmalchi

DOI: 10.2174/1570180811666140704172442

The Inhibition of Acetylshikonin on Bacteria and its Trypsin-like Protease and Glycosidic Enzyme may be Essential to Conquer Periodontal Ecological Niche

, 11(10): 1162 - 1166

Ming-Yu Li, Laikuan Zhu, Guang-Yun Lai, Sisu Mo and Jun Wang

DOI: 10.2174/1570180811666140704173134

Synthesis, Structure-Activity Relationship (SAR) Studies on some 4-Aryl-4Hchromenes and Relationship between Lipophilicity and Antitumor Activity

, 11(10): 1167 - 1176

Ahmed M. El-Agrody, Essam Shawky A. E. H. Khattab and Ahmed M. Fouda

DOI: 10.2174/1570180811666140623204655

Structural Characterization, Homology Modeling and Docking Studies of ARG674 Mutation in MyH8 Gene Associated with Trismus-Pseudocamptodactyly Syndrome

, 11(10): 1177 - 1187

Munazzah Tasleem, Romana Ishrat, Asimul Islam, Faizan Ahmad and Md. Imtaiyaz Hassan

DOI: 10.2174/1570180811666140717190217

Pd/C-mediated Synthesis of 3-methyleneisoindolin-1-ones: Biological and Theoretical Study of their PDE4 Inhibition

, 11(10): 1188 - 1198

Suryadevara Vijayavardhini, Dandela Rambabu, Vegendla Anuradha, Ravikumar Kapavarapu, Mandava Venkata Basaveswara Rao and Manojit Pal

DOI: 10.2174/1570180811666140717190618

Synthesis and Evaluation of Bis-pyrazoline Derivatives as Potential Antimicrobial Agents

, 11(10): 1199 - 1203

Mehlika Dilek Altıntop, Usama Abu Mohsen, Hulya Karaca, Zerrin Canturk and Ahmet Ozdemir

DOI: 10.2174/1570180811666140717185937

Synthesis and Analgesic Activity of 3,7-dimethylpurine-2,6-dion-1-yl Derivatives of Acetic and Butanoic Acid

, 11(10): 1204 - 1213

Mal gorzata Zygmunt, Pawe l Zmudzki, Graz yna Chl on -Rzepa, Jacek Sapa and Maciej Pawl owski

DOI: 10.2174/1570180811666140718162449

Development of 1, 3 Benzothiazol-2-yl Hydrazine Derivatives Containing Semicarbazone and Thioamide Pharmacophore as Anticonvulsants

, 11(10): 1214 - 1224

Ruhi Ali and Nadeem Siddiqui

DOI: 10.2174/1570180811666140627004353


Ivana Cacciatore
Department of Pharmacy
University "G. d'Annunzio" of Chieti-Pescara
Chieti Scalo
View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Ivana Cacciatore serves as the Editor-in-Chief of the journal.

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