Contents

Letters in Drug Design & Discovery, Volume 1 - Number 4

Graphical Abstracts

, 1(4): v


DOI: 10.2174/157018081040104000v




Novel Opportunities to Study and Block Interactions between Viruses and Cell Surface Heparan Sulfates by using Dispirotripiperazines

, 1(4): 293 - 299

M. Schmidtke, P. Wutzler and V. Makarov


DOI: 10.2174/1570180043398768




Cyclosporin A: A Therapeutic Strategy in Allergic Diseases

, 1(4): 300 - 307

Nettis Eustachio, Colanardi Maria Cristina and Ferrannini Antonio


DOI: 10.2174/1570180043398650




Novel Therapeutic Approaches to Mitochondrial Disease

, 1(4): 308 - 313

J. A. Ibdah and R. M. Payne


DOI: 10.2174/1570180043398506




Tuberculosis Therapeutics: Past Achievements, Present Road-Blocks and Future Perspectives

, 1(4): 314 - 328

Sanjay K. Garg, Marilina B. Santucci, Fouad Seghrouchni, Cesare Saltini, Prakash S. Bisen, Vittorio Colizzi and Maurizio Fraziano


DOI: 10.2174/1570180043398515




Anti-Angiogenic Activity of Quercetin and its Derivatives

, 1(4): 329 - 333

Kiminori Matsubara, Kohji Ishihara, Yoshiyuki Mizushina, Masaharu Mori and Nobuyoshi Nakajima


DOI: 10.2174/1570180043398533




Testosterone Based Esters as Inhibitors of Aromatase (AR) and the use of the Substrate-Haem Complex Approach in the Rationalisation of the Inhibitory Activity of these Compounds

, 1(4): 334 - 343

Shaheen Adat and Sabbir Ahmed


DOI: 10.2174/1570180043398579




Genetic Approaches for Finding Osteoporosis Genes: Implication for Clinical Therapeutics

, 1(4): 344 - 352

Dong-Hai Xiong, Robert R. Recker and Hong-Wen Deng


DOI: 10.2174/1570180043398669




Cancer Genetics and Drug Discovery in Mice

, 1(4): 353 - 360

Manuel Sanchez-Martín, Ines Gonzalez-Herrero and Isidro Sanchez-Garcia


DOI: 10.2174/1570180043398704




Design and Cytotoxicity Analysis of a Conjugate Containing the New DGalactose- Binding Lectin SELld and the Non-Toxic Type 2 Ribosome- Inactivating Protein Nigrin b

, 1(4): 361 - 367

Jorge Benitez, M. Angeles Rojo, Raquel Munoz, J. Miguel Ferreras, Pilar Jimenez and Tomas Girbes


DOI: 10.2174/1570180043398687




Altered Expression of Extra-Cellular Matrix Proteins and Integrin Receptors in Discoid Lupus Erythematosus

, 1(4): 368 - 371

Gianluigi Giannelli, Concetta Sgarra, Caterina Foti, Carlo Bergamini, Carmela Coviello, Giovanni Angelini and Salvatore Antonaci


DOI: 10.2174/1570180043398641




Three-Dimensional Pharmacophore Mapping of a Series of Isoxazolylpiperazine Inhibitors Selectively Acting on the Dopamine D4 Receptor

, 1(4): 372 - 379

In Young Lee, Yeon Joo Lee, Yong Seo Cho, Ae Nim Pae and Hun Yeong Koh


DOI: 10.2174/1570180043398722




Effect of Fenofibrate on the Concentration and Relative Distribution of LDL Subfractions in Patients with Combined Dyslipidemia

, 1(4): 380 - 383

V. Tsimihodimos, M. Elisaf, A. Tselepis, A. Tambaki and E. Bairaktari


DOI: 10.2174/1570180043398614




Solution-Phase Parallel Synthesis of N-Substituted Isoquinuclidines

, 1(4): 384 - 386

M. S. Levi, M. O.F. Khan and R. F. Borne


DOI: 10.2174/1570180043398597




Conformation of Roxatidine Acetate Hydrochloride by 1H, 13C and 15N NMR and AM1 Calculations and Its Interaction with Model Membranes Studied by 31P NMR

, 1(4): 387 - 395

Errol V. Mathias, Savita Tauro, Evans C. Coutinho and Uma P. Halkar


DOI: 10.2174/1570180043398551




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