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Letters in Drug Design & Discovery

Volume 16, 12 Issues, 2019
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access

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    Chemistry, Medicinal

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Most Cited Articles

Research Article

Synthesis and mosquiticidal activity of novel hydrazone containing pyrimidine derivatives against aedes aegypti

, 2018; 15(9): 951-956.

Zhong-Hua Shen, Zhao-Hui Sun, James J. Becnel, Alden Estep , David E. Wedge*, Cheng-Xia Tan, Jian-Quan Weng, Liang Han and Xing-Hai Liu*


DOI: 10.2174/1570180815666180102141640


Research Article

Synthesis, nematicidal activity and docking study of novel pyrazole-4-carboxamide derivatives against meloidogyne incognita

, 2018; 16(1): 29-35.

Long Cheng, Wen Zhao, Zhong-Hua Shen, Tian-Ming Xu, Hong-Ke Wu, Wei-Li Peng* and Xing-Hai Liu*


DOI: 10.2174/1570180815666180326150827


Research Article

Synthesis and antifungal activity of some 6-tert-butyl-8-chloro-2, 3-dimethylquinolin-4-ol derivatives against Pyricularia oryae

, 2018; 15(12): 1314-1318.

Yue-Ming Fang, Rui-Rui Zhang, Zhong-Hua Shen, Cheng-Xia Tan, Jian-Quan Weng, Tian-Ming Xu*, Xing-Hai Liu*, Hong-Ying Huang and Hong-Ke Wu


DOI: 10.2174/1570180815666180313121735


Research Article

Novel azole-functionalited flouroquinolone hybrids: Design, conventional and microwave irradiated synthesis, evaluation as antibacterial and antioxidant agents

, 2018; 15(1): 46-64.

Meltem Mentese, Neslihan Demirbas*, Arif Mermer, Serpil Demirci, Ahmet Demirbas and Faik Ahmet Ayaz


DOI: 10.2174/1570180814666170823163540


Research Article

Synthesis, biological evaluation and docking studies of 1,3,4-oxadiazole fused benzothiazole derivatives for anticancer drugs

, 2018; 15(12): 1299-1307.

Madala Subramanyam, Reddymasu Sreenivasulu, Rambabu Gundla, Mandava V.B. Rao and Koya Prabhakara Rao *


DOI: 10.2174/1570180815666180219165119


Research Article

Synthesis and biological evaluation of new quinoline-based thiazolyl hydrazone derivatives as potent antifungal and anticancer agents

, 1 February 2018; 15(2): 193-202.

Ali Erguc, Mehlika Dilek Altintop*, Ozlem Atli, Belgin Sever, Gokalp Iscan, Gozde Gormus and Ahmet Ozdemir


DOI: 10.2174/1570180814666171003145227


Letter

Synthesis, characterization and evaluation of gemfibrozil-stilbene hybrid as antioxidant agent

, 2018; 15(11): 1230-1238.

Rosa Amoroso, Lidia Leporini, Ivana Cacciatore, Lisa Marinelli, Alessandra Ammazzalorso, Isabella Bruno, Barbara De Filippis, Marialuigia Fantacuzzi, Cristina Maccallini, Luigi Menghini, Antonio Di Stefano and Letizia Giampietro*


DOI: 10.2174/1570180815666180321163246


Research Article

Biological activities and docking studies on novel bis 1,4-DHPS linked to arene core via ether or ester linkage

, 2018; 15(10): 1036-1045.

Nada S. Ibrahim, Magda F. Mohamed, Ahmed H. M. Elwahy* and Ismail A. Abdelhamid*


DOI: 10.2174/1570180815666180105162323




Research Article

6-methoxy-3,4-dihydronaphthalenone chalcone-like derivatives as potent tyrosinase inhibitors and radical scavengers

, 2018; 15(11): 1170-1179.

Sara Ranjbar, Abdolhossein Akbari, Najmeh Edraki, Mahsima Khoshneviszadeh, Hajar Hemmatian, Omidreza Firuzi and Mehdi Khoshneviszadeh*


DOI: 10.2174/1570180815666180219155027


Research Article

Design, synthesis, and screening of hybrid benzothiazolyl-oxadiazoles as anticonvulsant agents

, 1 April 2018; 15(4): 398-405.

Sheikh Murtuja, Mohammad Shaquiquzzaman and Mohammad Amir*


DOI: 10.2174/1570180814666170526154914


Research Article

Microwave-assisted synthesis and antifungal activity of novel 1,2,4-triazole thioether derivatives containing pyrimidine moiety

, 1 April 2018; 15(4): 347-352.

Meng Xu, Ya-Bo Zhu, Mei Wang, Ikhlas A. Khan, Xing-Hai Liu and Jian-Quan Weng*


DOI: 10.2174/1570180814666170602082440


Research Article

Efficient synthesis of ibandronate in the presence of an ionic liquid

, 1 January 2018; 15(7): 713-720.

David Illes Nagy, Alajos Grun, Oliver Pavela, Sandor Garadnay, Istvan Greiner and Gyorgy Keglevich*


DOI: 10.2174/1570180814666171027160324


Research Article

Synthesis and antioxidant evaluation of a new class of thienopyrimidinerhodanine hybrids

, 1 February 2018; 15(2): 118-126.

Kerru Nagaraju , Venkata H.S.S. Bhaskaruni, Ravada Kishore , Suresh Maddila*, Parvesh Singh and Sreekantha B. Jonnalagadda


DOI: 10.2174/1570180814666170710161844



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