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Letters in Drug Design & Discovery

Volume 18, 12 Issues, 2021
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Most Cited Articles


Research Article

(Substituted)-benzo[b]thiophene-4-carboxamide synthesis and antiproliferative activity study

, 2020; 17(5): 563-573.

Chandrakant Dhondiram Pawar, Dattatraya Navnath Pansare and Devanand Baburao Shinde*


DOI: 10.2174/1570180815666181004114125


Research Article

New 2-oxopyridine/2-thiopyridine derivatives tethered to a benzotriazole with cytotoxicity on MCF7 cell lines and with antiviral activities

, 2020; 17(2): 124-137.

Adel Mahmoud Attia, Ahmed Ibrahin Khodair*, Eman Abdelnasser Gendy, Mohammed Abu El-Magd and Yaseen Ali Mosa Mohamed Elshaier*


DOI: 10.2174/1570180816666190220123547


Research Article

Antimicrobial activity, antioxidant properties and phytochemical screening of aesculus hippocastanum mother tincture against food-borne bacteria

, 2020; 17(1): 48-56.

Maria Grazia Bonomo*, Caterina Cafaro, Daniela Russo, Luana Calabrone, Luigi Milella, Carmela Saturnino, Anna Capasso and Giovanni Salzano


DOI: 10.2174/1570180816666181108114115


Letter

One-pot synthesis of betulin triterpenoid quaternized pyridine derivatives and their antimicrobial activity

, 2020; 17(1): 79-84.

Elvira Rifovna Shakurova, Darina Alexandrovna Pozdnyakova, Elena Valeryevna Tretyakova and Lyudmila Vyacheslavovna Parfenova*


DOI: 10.2174/1570180816666181217123629



Research Article

Synthesis of limonin derivatives with improved anti-inflammatory and analgesic properties

, 2020; 17(3): 285-299.

Chengshu Jia, Bin Hu, Yingying Ji, Yourui Su, Guoqing Gong, Qihua Zhu and Yungen Xu*


DOI: 10.2174/1570180816666181113102359


Research Article

Lead molecules as novel aromatase inhibitors: In silico de novo designing and binding affinity studies

, 2020; 17(5): 655-665.

Laxmi Banjare, Sant Kumar Verma, Akhlesh Kumar Jain and Suresh Thareja*


DOI: 10.2174/1570180816666190703152659


Research Article

An environment-friendly synthesis of piperonal chalcones and their cytotoxic and antioxidant evaluation

, 2020; 17(2): 138-144.

Sanal Dev, Della Grace Thomas Parambi, Bency Baby, Githa Elizabeth Mathew, Hendawy Omnia Magdy, Monu Joy, Shine Sudev and Bijo Mathew*


DOI: 10.2174/1570180815666181016155934


Research Article

Anti-trypanosoma cruzi activity and molecular docking studies of 1H-pyrazolo[3, 4-b]pyridine derivatives

, 2020; 17(2): 184-191.

Camilo Henrique da Silva Lima, Júlio César de Araújo Vanelis Soares, Joana Lucius de Sousa Ribeiro, Estela Maris Freitas Muri, Sérgio de Albuquerque and Luiza Rosaria Sousa Dias*


DOI: 10.2174/1570180816666190305141733


Letter

Synthesis and antimicrobial activity of thiohydantoins obtained from L-amino acids

, 2020; 17(1): 94-102.

Priscila Goes Camargo de Carvalho, Jhonatan Macedo Ribeiro, Renata Perugini Biasi Garbin, Gerson Nakazato, Sueli Fumie Yamada Ogatta, Ângelo de Fátima, Marcelle de Lima Ferreira Bispo and Fernando Macedo*


DOI: 10.2174/1570180816666181212153011


Research Article

Identifying the structural features of diphenyl ether analogues for inha inhibition: A 2D and 3D QSAR based study

, 2020; 17(1): 31-47.

Ashutosh Prasad Tiwari, Varadaraj Bhat Giliyar*, Gurypur Gautham Shenoy and Vandana Kalwaja Eshwara


DOI: 10.2174/1570180816666190611153933


Research Article

Melatonin ameliorates radiation-induced sciatic nerve injury

, 2020; 17(1): 21-30.

Dheyauldeen Shabeeb*, Ahmed Eleojo Musa, Mansoor Keshavarz, Gholamreza Hassanzadeh, Mohammed Reza Hadian, Azin Nowrouzi, Alireza Shirazi* and Masoud Najafi


DOI: 10.2174/1570180816666190617160434


Research Article

Design, synthesis, in vitro and in silico evaluation of new hydrazone-based antitumor agents as potent akt inhibitors

, 2020; 17(11): 1380-1392.

Emine Merve Güngör, Mehlika Dilek Altıntop*, Belgin Sever and Gülşen Akalın Çiftçi


DOI: 10.2174/1570180817999200618163507


Review Article

Natural sesquiterpene lactones in the prevention and treatment of inflammatory disorders and cancer: A systematic study of this emerging therapeutic approach based on chemical and pharmacological aspect

, 2020; 17(9): 1102-1116.

Sudip Kumar Mandal, Utsab Debnath, Amresh Kumar, Sabu Thomas, Subhash Chandra Mandal, Manabendra Dutta Choudhury and Partha Palit*


DOI: 10.2174/1570180817999200421144007



Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)
Biography
View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05

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