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Letters in Drug Design & Discovery

Volume 17, 12 Issues, 2020
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access
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In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research

Articles Ahead of Print

Evaluation of Kaempferol as AKT Dependent mTOR Regulator via Targeting FKBP-12 in Hepatocellular Carcinoma: an In silico Approach


Pooja Siniprasad, Bhagyalakshmi Nair, Vaisali Balasubramaniam, Prashanth Sadanandan, Puliyapally Krishnan Krishnan Namboori and Lekshmi Reghu Nath*


DOI: 10.2174/1570180817999200623115703
View Abstract





Evaluating phenyl propanoids isolated from citrus medica as potential inhibitors for mitotic kinesin Eg5


Himesh Makala*, Venkatasubramanian Ulaganathan, Aravind Sivasubramanian, Narendran Rajendran and Shankar Subramanian


DOI: 10.2174/1570180817999200630125449
View Abstract




Design, Synthesis, Docking and Computational Pharmacokinetic Profiling of New Pyrazolinyl Thiazolinone Biheterocycles as Potent Antimicrobial Agents


Vinutha Vittala Salian, Badiadka Narayana*, Balladka Kunhanna Sarojini, Sharath Chandra Kodandoor and Anupam Glorious Lobo


DOI: 10.2174/1570180817999200623115049
View Abstract





Synthesis and evaluation of dapagliflozin ester prodrugs with improved hygroscopicity and thermal stability


Si Young Sung, Yu Na Chae, Dae Young Lee, Kyeong Min Kim, Eun Jung Kim, Ji Hye Han, Wook Kim and Sung-Hwa Yoon*


DOI: 10.2174/1570180817999200618162949
View Abstract


Anti-inflammatory Augmentation Therapy in Obsessive-compulsive Disorder: A Review


Hanie Ghasemi, Homa Nomani, Amirhossein Sahebkar* and Amir Hooshang Mohammadpour


DOI: 10.2174/1570180817999200520122910
View Abstract


Comparative Proteome Analysis of Mycobacterium tuberculosis Strains - H37Ra, H37Rv, CCDC5180, and CAS/NITR204: A Step Forward to Identify Novel Drug Targets


Shradheya R.R. Gupta, Ekta Gupta, Avnam Ohri, Sandeep Kumar Shrivastava, Sunita Kachhwaha, Vinay Sharma, Rupesh Kumar Mishra and Ravi Ranjan Kumar Niraj*


DOI: 10.2174/1570180817999200531165148
View Abstract









Discovery of New N-hydrazinecarbothioamide Indazole Hybrids: As Potential Radical (ABTS and DPPH) Scavengers


Rafaila Rafique, Arshia, Kanwal, Khalid Mohammed Khan*, Sridevi Chigurupati, Uzma Salar, Muhammad Taha and Shahnaz Perveen


DOI: 10.2174/1570180817999200424074455
View Abstract






Molecular Docking of 4-ehoxychalcones on Oxidoreductase/Pirin Inhibitors and Cytotoxic Evaluation on Breast/Skin Cancer Cell Lines


Kishori Ramachandra Harshitha, Balladka Kunhanna Sarojini*, Badiadka Narayana, Anupam Glorious Lobo and Bhuvanesh Sukhlal Kalal


DOI: 10.2174/1570180817666200129143803
View Abstract


In Vitro Characteristics of Glioma Cells Targeting by OX26-modified Liposomal Cisplatin


Maryam Sadat Ashrafzadeh, Amir Heydarinasab*, Azim Akbarzadeh and Mehdi Ardjmand


DOI: 10.2174/1570180817999200330165213
View Abstract


Fingerprint-based 2D-QSAR Models for Predicting Bcl-2 Inhibitors Affinity


Said Byadi, Mouhi Eddine Hachim, Karima Sadik, Črtomir Podlipnik and Aziz Aboulmouhajir*


DOI: 10.2174/1570180817999200414155403
View Abstract


Indole Curcumin Reverses Multidrug Resistance by Reducing the Expression of ABCB1 and COX2 in Induced Multidrug Resistant Human Lung Cancer Cells


Sankar Pajaniradje , Kumaravel Mohankumar, Rakesh Radhakrishnan , Shamim Akhtar Sufi, Srividya Subramanian , Parthiban Anaikutti, Surya Prakash Rao H and Rukkumani Rajagopalan *


DOI: 10.2174/1570180817666200402124503
View Abstract


Experimental Study of Therapeutic Efficacy of the Topical Preparation «Kourochitin» in Skin Allergy


Anna Klimovich*, Olga Styshova, Alexander Popov, Tatiana Moskvina , Valentin Stonik, Alexander Tsybulsky and Dmitry Derunov


DOI: 10.2174/1570180817666200316155643
View Abstract






Synthesis, Molecular Docking and α-Glucosidase Inhibitory Activity Study of 2,4,6-triaryl pyrimidine Derivatives


Mohammed Hussen Bule , Roghaieh Esfandyari, Tadesse Bekele Tafesse, Mohsen Amini*, Mohammad Ali Faramarzi and Mohammad Abdollahi


DOI: 10.2174/1570180817666200103130536
View Abstract



Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
(Czech Republic)

Biography View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.05

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