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Letters in Drug Design & Discovery

Volume 16, 12 Issues, 2019
ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)
This journal supports open access

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  • 57th of 61 in

    Chemistry, Medicinal

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Editor's Choice



The Structure of MT189-Tubulin Complex Provides Insights into Drug Design

, 2019; 16(9): 1069 - 1073

Zhongping Li, Lingling Ma, Chengyong Wu, Tao Meng, Lanping Ma, Wenyue Zheng, Yamei Yu*, Qiang Chen*, Jinliang Yang and Jingkang Shen


DOI: 10.2174/1570180816666181122122655









A New Class of Pure Estrogen Alpha Receptor Antagonists; Design, Synthesis and in-vitro Screening

, 2019; 16(1): 66 - 81

Akbar John Jameera Begam, Katike Ahamed Basheer, Selvaraj Jubie*, Srikanth Jupudi, Mohammed Afzal Azam and Palanisamy Dhanabal


DOI: 10.2174/1570180815666180327124634



Synthesis and Mosquiticidal Activity of Novel Hydrazone Containing Pyrimidine Derivatives against Aedes aegypti

, 2018; 15(9): 951 - 956

Zhong-Hua Shen, Zhao-Hui Sun, James J. Becnel, Alden Estep, David E. Wedge*, Cheng-Xia Tan, Jian-Quan Weng, Liang Han and Xing-Hai Liu*


DOI: 10.2174/1570180815666180102141640



Enhancement Antimicrobial Activity of Clarithromycin by Amine Functionalized Mesoporous Silica Nanoparticles as Drug Delivery System

, 2018; 15(7): 787 - 795

Pegah Khosravian, Mehdi Khoobi, Mehdi Shafiee Ardestani, Mohammad Porgham Daryasari, Malihe Hassanzadeh, Payam Ghasemi-Dehkordi, Massoud Amanlou and Hamid Akbari Javar*


DOI: 10.2174/1570180815666180117155818


Synthesis and Mosquitocidal Activity of a Series of Hydrazone Derivatives against Aedes aegypti

, 2018; 15(6): 671 - 677

Mehlika Dilek Altintop*, Nurhayat Tabanca, James J. Becnel, Jeffrey R. Bloomquist, Zafer Asim Kaplancikli and Ahmet Ozdemir


DOI: 10.2174/1570180814666171002155548




Antimicrobial, Gastroprotective and Healing Effect of the Hydroalcoholic Extract of Astronium fraxinifolium

, 2018; 15(3): 325 - 334

Anita Oliveira Brito Pereira Bezerra Martins, Ana Luiza Albuquerque Siebra, Cicera Datiane de Morais Oliveira, Gerlania Oliveira Leite, Henrique Douglas Melo Coutinho, Margareth Linde Athayde, Aline Augusti Bolignon, Jacqueline Cosmo Andrade, Larissa Rolim Oliveira, Marta Regina Kerntopf, Roseli Barbosa, Francisco Rafael Alves Santana Cesario, Thales Silva Coutinho, Lucindo Jose Quintans-Junior and Irwin Rose Alencar de Menezes*


DOI: 10.2174/1570180814666170213160114









Alzheimer’s Disease Drugs- In Vitro Comparison of Cholinesterase Inhibition and beta-amyloid Modulation

, 2017; 14(6): 743 - 750

Ondrej Holas, Jan Korabecny, Zuzana Gazova, Katarina Siposova, Kamil Musilek, Veronika Opletalova, Lukas Gorecki, Eugenie Nepovimova, Katarina Spilovska, Eva Mezeiova and Kamil Kuca*


DOI: 10.2174/1570180814666161228143846



Quinoline Derivatives as Novel Depigmenting and Antioxidant Agents

, 2017; 14(4): 374 - 379

Rebeca Mol Lima, Kauana Cristina de Souza, Jordana de Abreu Lazzarini, Isabela O. Souza, Adilson David da Silva and Nadia Rezende Barbosa Raposo


DOI: 10.2174/1570180813666160930164926


The Disulfide Analogues of Isophosphoramide Mustard for Anticancer Therapy

, 2015; 12(3): 172 - 179

Joanna Cytarska, Krzysztof Skowerski, Szymon Jaworski, Konrad Misiura, Beata Filip-Psurska and Joanna Wietrzyk


DOI: 10.2174/1570180811666141010001007








Analysis of Proteasome Inhibition Prediction Using Atom-Based Quadratic Indices Enhanced by Machine Learning Classification Techniques

, 2014; 11(6): 705 - 711

Gerardo M. Casanola-Martin, Huong Le-Thi-Thu, Yovani Marrero-Ponce, Juan A Castillo- Garit, Francisco Torrens, Facundo Perez-Gimenez and Concepcion Abad


DOI: 10.2174/1570180811666140122001144


Potent Neuroprotective Activity of Monoterpene Derived 4-[(3aR,7aS)- 1,3,3a,4,5,7a-Hexahydro-3,3,6-trimethylisobenzofuran-1-yl]-2-methoxyphenol in MPTP Mice Model

, 2014; 11(5): 611 - 617

Alla V. Pavlova, Irina V. Il'ina, Ekaterina A. Morozova, Dina V. Korchagina, Svetlana Yu. Kurbakova, Irina V. Sorokina, Tatyana G. Tolstikova, Konstantin P. Volcho and Nariman F. Salakhutdinov


DOI: 10.2174/1570180811666131210000316



Biochemical Changes Evidenced in Alzheimer's Disease: A Mini-Review

, 2014; 11(2): 240 - 248

Luciana Scotti, Francisco Jaime Bezerra Mendonça Junior, Marcelo Sobral da Silva, Ivan R. Pitta and Marcus Tullius Scotti


DOI: 10.2174/15701808113109990063





Editor-in-Chief

K. Kuca
University of Hradec Kralove
Hradec Kralove
Czech Republic

Biography View Full Editorial Board

Journal History

Letters in Drug Design & Discovery was introduced in 2004. Dr. Kamil Kuca serves as the Editor-in-Chief of the journal.
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