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"Letters in Drug Design & Discovery should be available in every library in the pharmaceutical industry and in universities."

R. F. Borne, Associate Director
Laboratory for Applied Drug Design and Synthesis, The University of Mississippi, USA

Forthcoming Special Issues

Opportunities and challenges in anticandidal drug discovery and development


Guest Editor(s): Mohammad Abid
Tentative Publication Date: July, 2017
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I would like to thank Bentham Science Publishers for their peerless effort to keep up scientists and students updated with the latest science and research work. Actually, Bentham assists researchers to achieve their goals to spread their reputation worldwide. I have experienced sincere, efficient and effective communication while dealing with Bentham team members. I intend to submit my work to Bentham and try to pick up journals that match my research profile. I have submitted a recent work to Medicinal Chemistry and nowadays I am drafting a manuscript targeting Current Pharmaceutical Design. Honestly, no words neither sentences would express my gratefulness and admiration. Bentham has offered my institution three months trial to access their journal lists and surf on its Board. This free access trial fulfills my literature review and broadens my horizon to absorb the recent research in pharmaceutical sciences and medicinal chemistry. Finally, I wish Bentham more success and achievement!

Dima Sabbah
(Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan)


Letters in Drug Design & Discovery

,

Volume 15

-

Number 3



Editorial





Research Article

Arginine- and Lysine-rich Peptides: Synthesis, Characterization and Antimicrobial Activity

, 15(3): 220 - 226

Adriano Mollica*, Giorgia Macedonio, Azzurra Stefanucci, Roberto Costante, Simone Carradori, Valentina Cataldi, Mara Di Giulio, Luigina Cellini, Romano Silvestri, Cesare Giordano, Anita Scipioni, Stefano Morosetti, Pasqualina Punzi and Sako Mirzaie


DOI: 10.2174/1570180814666170213161341






Research Article

In Vitro Evaluation of the Antibacterial Activity and Antibiotic- Modulatory Effect of Gracilaria cervicornis (Tuner) J. Agardh

, 15(3): 227 - 230

Israeliane F. Cordeiro, Henrique D. M. Coutinho, Joao V. A. Ferreira, Lucindo J. Quintans Junior*, Irwin R. A. Menezes, Micheline A. Lima, Thiago S. Freitas, Maria Isabeli P. Goncalo, Francisco Licaon G. Rocha, Rivio Fabricio de F. Furtado and Jacqueline C. Andrade


DOI: 10.2174/1570180814666170309094910






Research Article

Characterization and Evaluation of the Antioxidant Activity of Calamusenone, a Major Component of Hyptis pectinata (L.) Poit Essential Oil

, 15(3): 231 - 239

Mairim R. Serafini*, Daviane M.C. Vergne, Paula P. Menezes, Joao P.A. Santos, Thallita K. Rabelo, Shanmugam Saravanan, Pericles B. Alves, Emmanoel V. Costa, Hugo Cesar R. Jesus, Marcos J. Salvador, Daniel P. Gelain, Jose C.F. Moreira, Ricardo F. Rocha, Adriano A.S. Araujo* and Lucindo J. Quintans-Junior*


DOI: 10.2174/1570180814666170309130728






Research Article





Research Article

Effects of Asphodeline lutea Compounds on Toxicity Models in Isolated Rat Microsomes and Hepatocytes

, 15(3): 251 - 255

Magdalena Kondeva-Burdina, Rumyana Simeonova, Vessela Vitcheva, Irina Lazarova*, Reneta Gevrenova, Dimitrina Zheleva-Dimitrova, Gokhan Zengin and Nikolay D. Danchev


DOI: 10.2174/1570180814666170306122707






Research Article





Research Article

Chemical Constituent and Biological Activities of Spatoglossum asperum J. Agardh from Oman Sea

, 15(3): 263 - 269

Nasrin Movahhedin*, Hossein Nazemiyeh*, Jaleh Barar, Solmaz Esnaashari and Amir Hossein Movahhedin


DOI: 10.2174/1570180814666170407103936






Unveiling the Accuracy of Homology Modeling to Elucidate the Structure of GPCRs-HIV Co-receptor-CCR5 as a Case Study


Vadivelu Aanand , Rajendran Anitha , Somarathinam Kanagasabai , Gunalan Seshan , Changdev G Gadhe and Gugan Kothandan *


View Abstract


Antimicrobial Activities of Synthetic Arylidine Nicotinic and Isonicotinic Hydrazones


Muhammad Hayat, Khalid Mohammed Khan*, Sumayya Saeed, Uzma Salar, Momin Khan, Taimoor Baig, Aqeel Ahmad, Shahnaz Perveen and Muhammad Taha


View Abstract


Synthesis and Bioevaluation of Shikonin Derivatives


Sufen Cao, Jiangang Zhang and Wenhu Duan*


View Abstract


Synthesis and Mosquiticidal Activity of Novel Hydrazone Containing Pyrimidine Derivatives against Aedes aegypti


Zhong-Hua Shen, Zhao-Hui Sun, James J. Becnel, Alden Estep , David E. Wedge, Cheng-Xia Tan, Jian-Quan Weng, Liang Han and Xing-Hai Liu*


View Abstract


Theoretical Modeling and Systemic Analysis of Various Active Dipeptides and Analogues with 3D-QSAR Methods


Guanghui Tang, Ya Zhang, Cheng Chen, Yuping Zhang, Zhihua Lin* and Yuanqiang Wang


View Abstract


Design, Synthesis and anti-HIV-1 Activity of Modified Styrylquinolines


Shivani Mahajan , Shiv Gupta, Nisha Jariwala, Deepali Bhadane , Kamlesh Kumar Bhutani , Smita Kulkarni and Inder Pal Singh *


View Abstract


2-Indolinone Derivatives as Potent Urease Inhibitors


Momin Khan *, Muhammad Yousaf , Abdul Wadood , Zahid Hussain, Muhammad Naeem , Khalid Mohammed Khan and Shahnaz Perveen


View Abstract


Synthesis, Biological Evaluation and Docking studies of 1,3,4-Oxadiazole Fused Benzothiazole Derivatives for Anticancer Drugs


Madala Subramanyam, Reddymasu Sreenivasulu, M. V. Basaveswara Rao, Rambabu Gundla and Koya Prabhakara Rao *


View Abstract


New 1,3-oxazolylphosphonium salts as potential biocides: QSAR study, synthesis, antibacterial activity and toxicity evaluation


Maria M. Trush*, Vasyl Kovalishyn, Alla D. Ocheretniuk, Larisa E. Kalashnikova, Volodymyr M. Prokopenko, Oleksandr V. Holovchenko, Oleksandr L. Kobzar, Volodymyr S. Brovarets and Larisa O. Metelytsia


View Abstract


Synthesis and antioxidant activities of ferrocenyl-containing curcumin analogues


Xianjiao Meng, Shengling Li, Wenbing Ma*, Jianlong Wang, Zhiyong Hu and Duanlin Cao


View Abstract


6-Methoxy-3,4-dihydronaphthalenone Chalcone-like Derivatives as Potent Tyrosinase Inhibitors and Radical Scavengers


Sara Ranjbar, Abdolhossein Akbari, Najmeh Edraki, Mahsima Khoshneviszadeh, Hajar Hemmatian, Omidreza Firuzi and Mehdi Khoshneviszadeh*


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Synthetic aspects and first-time assessment of 2-amino-1,3-selenazoles against Mycobacterium tuberculosis


Victor Facchinetti, Marcus V. N. De Souza*, Ana C. S. Nery, Stephane L. Calixto, Juliana T. Granato, Elaine S. Coimbra, Maria C. S. Lourenco, Claudia R. B. Gomes and Thatyana R. A. Vasconcelos


View Abstract


Design, Synthesis and Biological Evaluation of Novel Dihydropyrimidine-2-Thione Derivatives as Potent Antimicrobial Agents: Experimental and Molecular Docking Approach


Ehsan Ullah Mughal*, Amina Sadiq, Muhammad Hamayun, Muhammad Naveed Zafar, Nighat Fatima, Syed Aun Muhammad, Amara Mumtaz, Muhammad Arfat Yameend, Ishtiaq Ahmed and Tehseen Fatima


View Abstract


Averrhoa bilimbi L. leaf aqueous extract modulate both cardiac contractility and frequency in the guinea-pig atrium by activation of muscarinic receptors


Anne Caroline Oliveira dos Santos, Diego Santos Souza, Thassio Ricardo Ribeiro Mesquita, Jose Evaldo Rodrigues de Menezes-Filho, Ana Paula Duarte Caldas, Americo Azevedo de Souza , Gilmara Beatriz Andrade da Silva , Evaleide Diniz de Oliveira*, Leonardo Rodrigues dos Santios and Carla Maria Lins de Vasconcelos


View Abstract


Inhibition of DNA topoisomerases by a series of benzoxazoles and their possible metabolites


Fatma Zilifdar*, Egemen Foto, Tugba Ertan-Bolelli, Ilkay Yildiz , Esin Aki-Yalcin and Nuran Diril


View Abstract


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