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"Letters in Drug Design & Discovery should be available in every library in the pharmaceutical industry and in universities."

R. F. Borne, Associate Director
Laboratory for Applied Drug Design and Synthesis, The University of Mississippi, USA

Forthcoming Special Issues

Opportunities and challenges in anticandidal drug discovery and development

Guest Editor(s): Mohammad Abid
Tentative Publication Date: July, 2017
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Authors' Comments
I would like to thank Bentham Science Publishers for their peerless effort to keep up scientists and students updated with the latest science and research work. Actually, Bentham assists researchers to achieve their goals to spread their reputation worldwide. I have experienced sincere, efficient and effective communication while dealing with Bentham team members. I intend to submit my work to Bentham and try to pick up journals that match my research profile. I have submitted a recent work to Medicinal Chemistry and nowadays I am drafting a manuscript targeting Current Pharmaceutical Design. Honestly, no words neither sentences would express my gratefulness and admiration. Bentham has offered my institution three months trial to access their journal lists and surf on its Board. This free access trial fulfills my literature review and broadens my horizon to absorb the recent research in pharmaceutical sciences and medicinal chemistry. Finally, I wish Bentham more success and achievement!

Dima Sabbah
(Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan)

Letters in Drug Design & Discovery


Volume 15


Number 3


Research Article

Arginine- and Lysine-rich Peptides: Synthesis, Characterization and Antimicrobial Activity

, 15(3): 220 - 226

Adriano Mollica*, Giorgia Macedonio, Azzurra Stefanucci, Roberto Costante, Simone Carradori, Valentina Cataldi, Mara Di Giulio, Luigina Cellini, Romano Silvestri, Cesare Giordano, Anita Scipioni, Stefano Morosetti, Pasqualina Punzi and Sako Mirzaie

DOI: 10.2174/1570180814666170213161341

Research Article

In Vitro Evaluation of the Antibacterial Activity and Antibiotic- Modulatory Effect of Gracilaria cervicornis (Tuner) J. Agardh

, 15(3): 227 - 230

Israeliane F. Cordeiro, Henrique D. M. Coutinho, Joao V. A. Ferreira, Lucindo J. Quintans Junior*, Irwin R. A. Menezes, Micheline A. Lima, Thiago S. Freitas, Maria Isabeli P. Goncalo, Francisco Licaon G. Rocha, Rivio Fabricio de F. Furtado and Jacqueline C. Andrade

DOI: 10.2174/1570180814666170309094910

Research Article

Characterization and Evaluation of the Antioxidant Activity of Calamusenone, a Major Component of Hyptis pectinata (L.) Poit Essential Oil

, 15(3): 231 - 239

Mairim R. Serafini*, Daviane M.C. Vergne, Paula P. Menezes, Joao P.A. Santos, Thallita K. Rabelo, Shanmugam Saravanan, Pericles B. Alves, Emmanoel V. Costa, Hugo Cesar R. Jesus, Marcos J. Salvador, Daniel P. Gelain, Jose C.F. Moreira, Ricardo F. Rocha, Adriano A.S. Araujo* and Lucindo J. Quintans-Junior*

DOI: 10.2174/1570180814666170309130728

Research Article

Research Article

Effects of Asphodeline lutea Compounds on Toxicity Models in Isolated Rat Microsomes and Hepatocytes

, 15(3): 251 - 255

Magdalena Kondeva-Burdina, Rumyana Simeonova, Vessela Vitcheva, Irina Lazarova*, Reneta Gevrenova, Dimitrina Zheleva-Dimitrova, Gokhan Zengin and Nikolay D. Danchev

DOI: 10.2174/1570180814666170306122707

Research Article

Research Article

Chemical Constituent and Biological Activities of Spatoglossum asperum J. Agardh from Oman Sea

, 15(3): 263 - 269

Nasrin Movahhedin*, Hossein Nazemiyeh*, Jaleh Barar, Solmaz Esnaashari and Amir Hossein Movahhedin

DOI: 10.2174/1570180814666170407103936

Unveiling the Accuracy of Homology Modeling to Elucidate the Structure of GPCRs-HIV Co-receptor-CCR5 as a Case Study

Vadivelu Aanand , Rajendran Anitha , Somarathinam Kanagasabai , Gunalan Seshan , Changdev G Gadhe and Gugan Kothandan *

View Abstract

Antimicrobial Activities of Synthetic Arylidine Nicotinic and Isonicotinic Hydrazones

Muhammad Hayat, Khalid Mohammed Khan*, Sumayya Saeed, Uzma Salar, Momin Khan, Taimoor Baig, Aqeel Ahmad, Shahnaz Perveen and Muhammad Taha

View Abstract

Synthesis and Bioevaluation of Shikonin Derivatives

Sufen Cao, Jiangang Zhang and Wenhu Duan*

View Abstract

Synthesis and Mosquiticidal Activity of Novel Hydrazone Containing Pyrimidine Derivatives against Aedes aegypti

Zhong-Hua Shen, Zhao-Hui Sun, James J. Becnel, Alden Estep , David E. Wedge, Cheng-Xia Tan, Jian-Quan Weng, Liang Han and Xing-Hai Liu*

View Abstract

Theoretical Modeling and Systemic Analysis of Various Active Dipeptides and Analogues with 3D-QSAR Methods

Guanghui Tang, Ya Zhang, Cheng Chen, Yuping Zhang, Zhihua Lin* and Yuanqiang Wang

View Abstract

Design, Synthesis and anti-HIV-1 Activity of Modified Styrylquinolines

Shivani Mahajan , Shiv Gupta, Nisha Jariwala, Deepali Bhadane , Kamlesh Kumar Bhutani , Smita Kulkarni and Inder Pal Singh *

View Abstract

2-Indolinone Derivatives as Potent Urease Inhibitors

Momin Khan *, Muhammad Yousaf , Abdul Wadood , Zahid Hussain, Muhammad Naeem , Khalid Mohammed Khan and Shahnaz Perveen

View Abstract

Synthesis, Biological Evaluation and Docking studies of 1,3,4-Oxadiazole Fused Benzothiazole Derivatives for Anticancer Drugs

Madala Subramanyam, Reddymasu Sreenivasulu, M. V. Basaveswara Rao, Rambabu Gundla and Koya Prabhakara Rao *

View Abstract

New 1,3-oxazolylphosphonium salts as potential biocides: QSAR study, synthesis, antibacterial activity and toxicity evaluation

Maria M. Trush*, Vasyl Kovalishyn, Alla D. Ocheretniuk, Larisa E. Kalashnikova, Volodymyr M. Prokopenko, Oleksandr V. Holovchenko, Oleksandr L. Kobzar, Volodymyr S. Brovarets and Larisa O. Metelytsia

View Abstract

Synthesis and antioxidant activities of ferrocenyl-containing curcumin analogues

Xianjiao Meng, Shengling Li, Wenbing Ma*, Jianlong Wang, Zhiyong Hu and Duanlin Cao

View Abstract

6-Methoxy-3,4-dihydronaphthalenone Chalcone-like Derivatives as Potent Tyrosinase Inhibitors and Radical Scavengers

Sara Ranjbar, Abdolhossein Akbari, Najmeh Edraki, Mahsima Khoshneviszadeh, Hajar Hemmatian, Omidreza Firuzi and Mehdi Khoshneviszadeh*

View Abstract

Synthetic aspects and first-time assessment of 2-amino-1,3-selenazoles against Mycobacterium tuberculosis

Victor Facchinetti, Marcus V. N. De Souza*, Ana C. S. Nery, Stephane L. Calixto, Juliana T. Granato, Elaine S. Coimbra, Maria C. S. Lourenco, Claudia R. B. Gomes and Thatyana R. A. Vasconcelos

View Abstract

Design, Synthesis and Biological Evaluation of Novel Dihydropyrimidine-2-Thione Derivatives as Potent Antimicrobial Agents: Experimental and Molecular Docking Approach

Ehsan Ullah Mughal*, Amina Sadiq, Muhammad Hamayun, Muhammad Naveed Zafar, Nighat Fatima, Syed Aun Muhammad, Amara Mumtaz, Muhammad Arfat Yameend, Ishtiaq Ahmed and Tehseen Fatima

View Abstract

Averrhoa bilimbi L. leaf aqueous extract modulate both cardiac contractility and frequency in the guinea-pig atrium by activation of muscarinic receptors

Anne Caroline Oliveira dos Santos, Diego Santos Souza, Thassio Ricardo Ribeiro Mesquita, Jose Evaldo Rodrigues de Menezes-Filho, Ana Paula Duarte Caldas, Americo Azevedo de Souza , Gilmara Beatriz Andrade da Silva , Evaleide Diniz de Oliveira*, Leonardo Rodrigues dos Santios and Carla Maria Lins de Vasconcelos

View Abstract

Inhibition of DNA topoisomerases by a series of benzoxazoles and their possible metabolites

Fatma Zilifdar*, Egemen Foto, Tugba Ertan-Bolelli, Ilkay Yildiz , Esin Aki-Yalcin and Nuran Diril

View Abstract

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