ISSN: 1875-628X (Online)
ISSN: 1570-1808 (Print)

Volume 14, 12 Issues, 2017

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Letters in Drug Design & Discovery

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G. Perry
University of Texas
San Antonio, TX

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Abstracts Ahead of Print

2-Indolinone Derivatives as Potent Urease Inhibitors

Momin Khan *, Muhammad Yousaf , Abdul Wadood , Zahid Hussain, Muhammad Naeem , Khalid Mohammed Khan and Shahnaz Perveen.

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The Possible Potency of Ocimum basilicum New Constituent on Glucose-stimulated Insulin Secretion In vitro and β-cell Function In vivo

Huma Aslam Bhatti , Kiran Maryam , Rizwana S. Waraich , Abdul Hameed and Rahman M Hafizur.

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Synthesis, surface properties and antimicrobial effect of hydroxymethyl-substituted pyridinium salts

Kamil Kuca*.

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Rational design, synthesis and biological evaluation of novel derivatives based on in vivo metabolism of natural product β-elemene

Renren Bai*, Xiaokang Jie , Eric Salgado , Jian Sun, Yao Zhu, Thomas Pickel , Yuanyuan Xie, Jichao Chen and Jinyi Xu.

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Theoretical modeling and systemic analysis of various active dipeptides and analogues with 3D-QSAR methods

Guanghui Tang, Ya Zhang, Cheng Chen, Yuping Zhang, Zhihua Lin* and Yuanqiang Wang.

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Antihelmintic Activity of Some 2-Substituted Thieno[2,3-d]pyrimidine-4-ones

Anelia Mavrova, Stefan Dimov, Dimitar Vutchev, Kameliya Anichina and Denitsa Yancheva*.

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Synthesis, Characterization, Biological activity of novel 1H-benzo[f]-chromene and 12H-benzo[f]chromeno[2,3-d]pyrimidine derivatives

Heba K. Abd El-Mawgoud, Hebat Allah M. Radwan, Fatma El-Mariah and Ahmed M El-Agrody *.

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Efficient Synthesis of Ibandronate in the Presence of an Ionic Liquid

David Illes Nagy, Alajos Grun, Oliver Pavela, Sandor Garadnay, Istvan Greiner and Gyorgy Keglevich*.

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3D-QSAR modeling of some S-trityl-L-Cysteine analogues as inhibitors of mitotic kinesin Eg5 by CoMFA, CoMSIA and H-QSAR methodologies

Fatemeh Mousavi* and Mohammad Hossein Fatemi*.

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Enhanced Antibacterial Activity of endo-nortropine substituted (C-7) Fluoroquinolones against V. cholerae, S. aureus and B. subtilis

Ramkrushna Ashok Salunke, Chandni Sidhu, Ashok Rana, Anil Kumar Pinnaka, Baldev Raj Bansal and Manmohan Chhibber*.

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4-Acetamidobenzaldehyde derivatives as biological active candidates; Synthesis, anti-oxidant, anti-Alzheimer and DNA binding studies

Shahzad Murtaza* and Adina Tatheer.

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Synthesis, Biological Evaluation and Docking studies of N-(2-benzamido feruloyl) Aryl hydrazone Analogues

M. Soujanya * and G Rajitha.

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Molecular and cellular mechanism of cutaneous injuries due to exposure to sulfur mustard

Yunes Panahi , Seyyed Mahdi Rajaee and Amirhossein Sahebkar*.

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Synthesis, biological evaluation and computational study of new quinoline hybrids as antitubercular agent

Zahid Zaheer*, Sameer I. Shaikh, Santosh N. Mokale and Deepak K Lokwani.

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Reactivation Potential of Novel More Lipophilic Pralidoxime Analogs

Martina Hrabinova, Jan Misik, Daniel Jun and Kamil Kuca.

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Novel Hybrid Molecules Of Quinazoline Chalcone Derivatives: Synthesis And Study Of Invitro Cytotoxic Activities

Arunkumar Thiriveedhi*, Ratnakaram Venkata Nadh, Navuluri Srinivasu and Kishore Kaushal.

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Inhibitory effects of 1,4-disubstituted thiosemicarbazide derivatives on Streptococcus mutans and Streptococcus sanguinis mono-species biofilms

Malgorzata Miazga-Karska, Maciej Wos, Agnieszka A. Kaczor, Anna Pachuta-Stec, Grazyna Ginalska and Monika Pitucha*.

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Synthesis and biological activity of new Schiff bases of benzylideneamine bearing thiophene, 1,2,4-triazolone, 1,3,4-oxadiazole , morpholine moieties

Yasemin Unver* and Ersan Bektas.

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Synthesis, Pharmacological Evaluation and Docking Study of a New Modulator of Microtubule Polymerization

Teiliane R. Carneiro, Daniel N. do Amaral, Harold H. Fokoue, Carlos M.R. Sant`Anna, Maria L.G. Porras, Cláudia Pessoa, Augusto C.A. Oliveira, Eliezer J Barreiro, Bruno C. Cavalcanti and Lidia Moreira Lima.

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Synthesis, aqueous solubility, metabolic stability and pharmacological profile of simplified urea derivatives

Raquel de Oliveira Lopes, Roberta Olmo Pinheiro, Cristina Setim Freitas, Fernando Q Cunha, Eliezer J. Barreiro* and Lídia Moreira Lima.

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Synthesis and in vitro evaluation of 1,2,3-triazole-4-chloromethylcoumarins with antioxidant activity

Anna Carolina Schneider Alves, Thais Munhoz, Fabiana Gomes Nascimento Soares, Liliana Rockenbach, Bruna Gauer, Daniel Fabio Kawano, Gilsane Lino von Poser,, Solange Cristina Garcia and Vera Lucia Eifler-Lima*.

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Review of medicinal plants and their compounds for aldose reductase inhibitory activity

Saliha Bouknana, Mohamed Bouhrim, Hayat Ouassou and Mohamed Bnouham*.

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3D QSAR studies of tricyclic compounds as Porcupine Inhibitors for Wnt pathway inhibitory activity

Liqiang Meng, Liqian Sun, Chaoqun Yan, Dongxiao Cui, Jingrun Chen, Taigang Liang* and Qingshan Li.

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Antimicrobial Activities of Synthetic Arylidine Nicotinic and Isonicotinic Hydrazones

Muhammad Hayat, Khalid Mohammed Khan*, Sumayya Saeed, Uzma Salar, Momin Khan, Taimoor Baig, Aqeel Ahmad, Shahnaz Perveen and Muhammad Taha.

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