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Abstracted/Indexed in


"Letters in Drug Design & Discovery should be available in every library in the pharmaceutical industry and in universities."

R. F. Borne, Associate Director
Laboratory for Applied Drug Design and Synthesis, The University of Mississippi, USA

Forthcoming Special Issues

Opportunities and challenges in anticandidal drug discovery and development

Guest Editor(s): Mohammad Abid
Tentative Publication Date: April, 2018
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Published Special Issues


Letters in Drug Design & Discovery, Volume 15, Number 03
Guest Editor(s): Gokhan Zengin, Marcello Locatelli

Authors' Comments
I would like to thank Bentham Science Publishers for their peerless effort to keep up scientists and students updated with the latest science and research work. Actually, Bentham assists researchers to achieve their goals to spread their reputation worldwide. I have experienced sincere, efficient and effective communication while dealing with Bentham team members. I intend to submit my work to Bentham and try to pick up journals that match my research profile. I have submitted a recent work to Medicinal Chemistry and nowadays I am drafting a manuscript targeting Current Pharmaceutical Design. Honestly, no words neither sentences would express my gratefulness and admiration. Bentham has offered my institution three months trial to access their journal lists and surf on its Board. This free access trial fulfills my literature review and broadens my horizon to absorb the recent research in pharmaceutical sciences and medicinal chemistry. Finally, I wish Bentham more success and achievement!

Dima Sabbah
(Department of Pharmacy, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman, Jordan)

Letters in Drug Design & Discovery


Volume 15


Number 4


Research Article

Research Article

Research Article

Anti-MRSA (Multidrug Resistant Staphylococcus aureus) Activity of 3-Substituted Coumarins

, 15(4): 353 - 362

Uzma Salar, Khalid Mohammed Khan*, Humaira Muhammad, Muhammed Imran Fakhri, Sanaullah, Shahnaz Perveen and Muhammed Iqbal Choudhary

DOI: 10.2174/1570180814666170619121844

Research Article

Synthesis and Anti-influenza Activity of Novel Thiadiazole, Oxadiazole and Triazole Based Scaffolds

, 15(4): 363 - 374

Samar S. Tawfik, Abdelbasset A. Farahat*, Magda A.-A El-Sayed, Atif S. Tantawy, Ola Bagato and Mohamed A. Ali

DOI: 10.2174/1570180814666170512122832

Research Article

Exploration of Some Thiazolidine-2,4-dione and 2-Oxoindoline Derivatives Incorporating 3,4,5-Trimethoxybenzyl Moiety as Novel Anticancer Agents

, 15(4): 375 - 387

Le Cong Huan, Hai Pham-The, Huong Le-Thi-Thu, Tran Phuong Thao, Do Nguyet Que, Nguyen-Thu Trang, Phan Thi Phuong Dung, Minji Pyo, Sang-Bae Han, Nguyen Thi Thuan* and Nguyen-Hai Nam*

DOI: 10.2174/1570180814666170605122552

Research Article

Research Article

Molecular Docking and 3D-QSAR Studies on 7-azaindole Derivatives as Inhibitors of Trk A: A Strategic Design in Novel Anticancer Agents

Adnane Aouidate*, Adib Ghaleb, Mounir Ghamali, Samir Chtita, Abdellah Ousaa, M`barek Choukrad, Abdelouahid Sbai, Mohammed Bouachrine and Tahar Lakhlifi

View Abstract

Plant Antioxidants and Mechanisms of Action

Weslley Felix de Oliveira, Priscila Marcelino dos Santos Silva, Luana Cassandra Breitenbach Barroso Coelho and Maria Tereza dos Santos Correia *

View Abstract

Synthesis and Cytotoxic Activity of 2,6-Diarylidenecyclohexanones and their 6-Amino-1,3-dimethyluracil Monoadducts

Erika Madeleyne Ramos-Rivera , Cuauhtemoc Alvarado, Jose D. Solano, Luis Roa de la Fuente, Angeles Dominguez-Rivera, Miguel Angel Vilchis-Reyes* and Miguel Angel Martinez-Urbina

View Abstract

Enhancement Antimicrobial Activity of Clarithromycin by Amine Functionalized Mesoporous Silica Nanoparticles as Drug Delivery System

Pegah Khosravian, Mehdi Khoobi, Mehdi Shafiee Ardestani, Mohammad Porgham Daryasari, Malihe Hassanzadeh, Payam Ghasemi-Dehkordi, Massoud Amanlou and Hamid Akbari Javar*

View Abstract

Synthesis and Antibacterial/Antitubercular/Antioxidant Activities of Compounds Containing Fluoroquinolone Ring Linked to a 4-thiazolidinone Moiety

Tejeswara Rao Allaka, Naresh Kumar Katari, Venkanna Banothu, Srinubabu Maddela, Jaya Shree Anireddy and Manojit Pal *

View Abstract

Unveiling the Accuracy of Homology Modeling to Elucidate the Structure of GPCRs-HIV Co-receptor-CCR5 as a Case Study

Vadivelu Aanand , Rajendran Anitha , Somarathinam Kanagasabai , Gunalan Seshan , Changdev G Gadhe and Gugan Kothandan *

View Abstract

Antimicrobial Activities of Synthetic Arylidine Nicotinic and Isonicotinic Hydrazones

Muhammad Hayat, Khalid Mohammed Khan*, Sumayya Saeed, Uzma Salar, Momin Khan, Taimoor Baig, Aqeel Ahmad, Shahnaz Perveen and Muhammad Taha

View Abstract

Synthesis and Antifungal Activity of Some 6-tert-butyl-8-chloro-2, 3-dimethylquinolin-4-ol Derivatives against Pyricularia oryae

Yue-Ming Fang, Rui-Rui Zhang, Zhong-Hua Shen, Cheng-Xia Tan, Jian-Quan Weng, Tian-Ming Xu, Xing-Hai Liu*, Hong-Ying Huang and Hong-Ke Wu

View Abstract

Synthesis and Anticancer Properties of Methyl N1-(thien-4-yl)amidrazone-3-carboxylates

Ali M. Almansour, Jalal A. Zahra*, Salim S. Sabri, Mustafa M. El-Abadelah, Malik A. Zihlif and Mutasem O. Taha

View Abstract

Synthesis and cytotoxicity evaluation of novel tricyclic dihydropyrazolo[4,3-f][1,2,3]triazolo diazepines

Chiranjeevi Bingi, Ashok Kale, Y Poornachandra, C Ganesh Kumar and Krishnaiah Atmakur*

View Abstract

Synthesis, Biological Evaluation and Docking studies of 1,3,4-Oxadiazole Fused Benzothiazole Derivatives for Anticancer Drugs

Madala Subramanyam, Reddymasu Sreenivasulu, M. V. Basaveswara Rao, Rambabu Gundla and Koya Prabhakara Rao *

View Abstract

New 1,3-oxazolylphosphonium salts as potential biocides: QSAR study, synthesis, antibacterial activity and toxicity evaluation

Maria M. Trush*, Vasyl Kovalishyn, Alla D. Ocheretniuk, Larisa E. Kalashnikova, Volodymyr M. Prokopenko, Oleksandr V. Holovchenko, Oleksandr L. Kobzar, Volodymyr S. Brovarets and Larisa O. Metelytsia

View Abstract

Synthesis and antioxidant activities of ferrocenyl-containing curcumin analogues

Xianjiao Meng, Shengling Li, Wenbing Ma*, Jianlong Wang, Zhiyong Hu and Duanlin Cao

View Abstract

6-Methoxy-3,4-dihydronaphthalenone Chalcone-like Derivatives as Potent Tyrosinase Inhibitors and Radical Scavengers

Sara Ranjbar, Abdolhossein Akbari, Najmeh Edraki, Mahsima Khoshneviszadeh, Hajar Hemmatian, Omidreza Firuzi and Mehdi Khoshneviszadeh*

View Abstract

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