Contents

Infectious Disorders - Drug Targets , Volume 6 - Number 1

Editorial: Novel Therapeutic Approaches for HCV Chronic Infections [Hot Topic: HCV Drug Discovery and Development and Clinical Issues Related to Co-Infection with HIV (Guest Editors: Raffaele De Francesco and Giovanni Migliaccio)]

, 6(1): 1 - 2

Raffaele D. Francesco and Giovanni Migliaccio


DOI: 10.2174/187152606776056670




Discovery and Development of VX-950, a Novel, Covalent, and Reversible Inhibitor of Hepatitis C Virus NS3.4A Serine Protease

, 6(1): 3 - 16

C. Lin, A. D. Kwong and R. B. Perni


DOI: 10.2174/187152606776056706




Nucleoside Analog Inhibitors of Hepatitis C Virus Replication

, 6(1): 17 - 29

S. S. Carroll and D. B. Olsen


DOI: 10.2174/187152606776056698




Allosteric Inhibition of the Hepatitis C Virus NS5B RNA Dependent RNA Polymerase

, 6(1): 31 - 41

Uwe Koch and Frank Narjes


DOI: 10.2174/187152606776056724




Future Promise of siRNA and Other Nucleic Acid Based Therapeutics for the Treatment of Chronic HCV

, 6(1): 43 - 56

J. A. Wilson and C. D. Richardson


DOI: 10.2174/187152606776056689




Chronic Hepatitis C in HIV-Infected Patients: Those Who More Need Therapy are Those Who Respond Less

, 6(1): 57 - 68

Vincent Soriano, Marina Nunez, Javier Garcia-Samaniego, Pablo Labarga, Nuria Simarro, Luz Martin-Carbonero, Miriam Romero, Belen Ramos and Pablo Barreiro


DOI: 10.2174/187152606776056715




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