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Infectious Disorders - Drug Targets

Formerly: Current Drug Targets - Infectious Disorders

Volume 22, 8 Issues, 2022
ISSN: 2212-3989 (Online)
ISSN: 1871-5265 (Print)
This journal supports open access

Aims & Scope

Infectious Disorders - Drug Targets aims to cover all the latest and outstanding developments in medicinal chemistry, pharmacology, molecular biology, genomics and biochemistry of contemporary molecular targets involved in infectious disorders e.g. disease specific proteins, receptors, enzymes, genes. Each issue of the journal contains a series of timely in-depth reviews/mini-reviews and research articles written by leaders in the field covering a range of current topics on drug targets involved in infectious disorders. As the discovery, identification, characterization and validation of novel human drug targets for anti-infective drug discovery continue to grow, this journal will be essential reading for all pharmaceutical scientists involved in drug design, discovery and development. All aspects related to viral or bacterial diseases including HIV, AIDS and other sexually transmitted diseases (STDs) are also included in the scope of the journal.

Infectious Disorders - Drug Targets


Volume 22


Number 5



SARS-CoV-2-Induced Neurological Disorders in Symptomatic Covid-19 and Long Covid Patients: Key Role of Brain Renin-Angiotensin System

, 22(5): e060422203203

Ziad Fajloun*, Hervé Kovacic, Cédric Annweiler, Yingliang Wu, Zhijian Cao and Jean-Marc Sabatier*

DOI: 10.2174/1871526522666220406124618

Review Article

COVID-19 Infection in Pregnancy: A Review

, 22(5): e050122199976

Sabrina Jahan Mily, Kazi Mahmuda Akter, Nowshin Jabin, Saikat Mitra, Talha Bin Emran, Monisha Nandi, Sumit Kumar Baral, Md. Zia Uddin, Jewel Mallick, Arkajyoti Paul, Syed Uzair Ali Shah, Abdur Rauf, Ishaq N. Khan and Mohammad S. Mubarak*

DOI: 10.2174/1871526522666220105111358

Review Article

Review Article

Systematic Review Article

COVID-19 in Pediatrics: A Systematic Review of Current Knowledge and Practice

, 22(5): e290921196908

Esmaeil Mehraeen, Shahram Oliaei, SeyedAhmad SeyedAlinaghi*, Amirali Karimi, Pegah Mirzapour, Amir Masoud Afsahi, Alireza Barzegary, Farzin Vahedi, Mahdi Soleymanzadeh, Farzane Behnezhad, Mohammad Javaherian, Ghazal Zargari, Seyed Peyman Mirghaderi, Tayebeh Noori and Jean-Marc Sabatier

DOI: 10.2174/1871526521666210929121705

Infectious Disorders - Drug Targets, Volume 22 (2022) - Number 6

This issue is in progress but contains articles that are final and fully citable.

Articles Ahead of Print

Epigenetic-related Effects of COVID-19 on Human Cells

Arezoo Faramarzi, Reza Safaralizadeh*, Narges Dastmalchi and Shahram Teimourian

DOI: 10.2174/1871526522666220420093029
View Abstract View on PubMed

An Insight of Clinical Evidence of Ayurveda Interventions in the Management of COVID-19 Patients

Naina Mohamed Pakkir Maideen*, Rajkapoor Balasubramaniam, Gobinath Manavalan, Kumar Balasubramanian, Nivedhitha Subramanian, Thirumal Murugesan and Vasanth Kumar Solaimalai

DOI: 10.2174/1871526522666220321152504
View Abstract View on PubMed

The Effect of Curcumin on the Expression of INFγ, TNF-α, and iNOS Genes in PBMCs Infected with Leishmania major [MRHO/IR/75/ER]

Soheila Alinejad, Shahram Khademvatan*, Shahla Amani*, Negar Asadi, Khosrow Hazrati Tappeh, Elham Yousefi and Touraj Miandoabi

DOI: 10.2174/1871526522666220404083220
View Abstract View on PubMed

Abstracts Ahead of Print

The prevalence of early toxoplasmosis after bone marrow transplantation using PCR, a study in Iranian patients

Sara Abolghasemi, Sepideh Khederzadeh, Sina Salari*, Masoud Mardani, Zahra ArabMazar, Mona Ettefaghi, Ramiz Kamrani and Mahmoud Dehghani Ghorbi

DOI: 10.2174/1871526522666220622102543
View Abstract

Disseminated cryptococcosis in Idiopathic CD4+ lymphocytopenia

Ankita Dewangan, Jitendra Singh, Dinesh Kumar, Nilesh Kumar, Kailash Kumar and Anju Dinkar*

DOI: 10.2174/1871526522666220621110723
View Abstract

Prevalence of Hepatitis in Prisoners: A Systematic Review of Current Evidence

Salar Pashangzadeh, Seyed Ahmad Seyed Alinaghi, Omid Dadras, Zahra Pashaei, Mahdi Soleymanzadeh, Alireza Barzegary, Pegah Mirzapour, Farzin Vahedi, Amirata Fakhfouri, Tayebeh Noori, Seyed Mohammad Hossein Irani, Esmaeil Mehraeen* and Shayesteh Jahanfar

DOI: 10.2174/1871526522666220620115006
View Abstract

MMP3 in Severe COVID-19: A Biomarker or Therapeutic Target?

Sultan Almuntashiri, Duo Zhang, Payaningal R. Somanath and Andrea Sikora

DOI: 10.2174/1871526522666220619121539
View Abstract

Extensive multifocal emphysematous osteomyelitis of spine: A rare case and a review of literature

Bhawna Sharma, Vikas Lakhanpal, Abeer Goyal, Ritu Shree, Shashank Raj, Priya Sreenivasan, Manisha Biswal, Pallab Ray and Archana Angrup*

DOI: 10.2174/1871526522666220614163310
View Abstract


Praveen Kumar uppala, Anjaly Mary Varghese, Sree Sudha TY*, Hemasri Velmurugan, Pugazhenthan Thangaraju and K.S.B.S. Krishna Sasanka

DOI: 10.2174/1871526522666220614162117
View Abstract

Postural orthostatic tachycardia syndrome and orthostatic hypotension post COVID-19

Masoud Eslami, Reza Mollazadeh, Shayan Mirshafiee, Parisa Sehat, Fatemeh Alizadeh, Zahra Emkanjoo, Vahideh Laleh far and Elnaz Shahmohamadi*

DOI: 10.2174/1871526522666220610143504
View Abstract

Published Contents

Editor's Choice

Transmission Modes of COVID-19: A Systematic Review

, 2021; 21(6): 6 - 13

Esmaeil Mehraeen, Mohammad Amin Salehi, Farzane Behnezhad, Hamed Rezakhani Moghaddam and SeyedAhmad SeyedAlinaghi*

DOI: 10.2174/1871526520666201116095934

Ocular COVID-19: Eyes as a Reservoir to Conceal and Spread SARSCoV- 2

, 2021; 21(4): 480 - 483

Abdul Mannan Baig*, Saara Ahmad, Areeba Khaleeq, Hamna Rafique, Shafiqa Rajput, Mehaer Angez, Ayesha Hameed, Talha Nawaz and Preet Katyara

DOI: 10.2174/1871526520999200729182242

Pleural Effusion as a Sign of Coronavirus Disease 2019 (COVID-19) Pneumonia: A Case Report

, 2021; 21(3): 468 - 472

Zahra Ahmadinejad, Faeze Salahshour, Omid Dadras, Hesan Rezaei and SeyedAhmad SeyedAlinaghi*

DOI: 10.2174/1871526520666200609125045

Clinical Effectiveness of a High Dose Versus the Standard Dose of Meropenem in Ventilator-associated Pneumonia Caused by Multidrugresistant Bacteria: A Randomized, Single-blind Clinical Trial

, 2021; 21(2): 274 - 283

Mahila Monajati, Shahram Ala*, Masoud Aliyali, Roya Ghasemian, Fatemeh Heidari, Mohammad Ahanjan, Siavash Moradi, Ali Sharifpour, Mojtaba Mojtahedzadeh and Ebrahim Salehifar

DOI: 10.2174/1871526520666200227102013

Monoclonal Antibodies Against Infectious Microbes: So Long and Too Little!

, 2021; 21(1): 4 - 27

Gerard M. Raj*, Rekha Priyadarshini, Sakthibalan Murugesan and Mangaiarkkarasi Adhimoolam

DOI: 10.2174/1871526520666200312154649

The In Vitro Study of Anti-leishmanial Effect of Naja naja oxiana Snake Venom on Leishmania major

, 2020; 20(6): 913 - 919

Nastaran Fallahi, Delavar Shahbazzadeh, Fatemeh Maleki, Marjaneh Aghdasi, Fatemeh Tabatabaie* and Khadijeh Khanaliha*

DOI: 10.2174/1871526520666200106121839

Clinical and Epidemiologic Features of Visceral Leishmaniasis in Children: A 6-year Study from an Iranian Referral Hospital

, 2020; 20(4): 461 - 466

Mohamadreza Abdolsalehi, Babak Pourakbari, Shima Mahmoudi, Mina Moradzadeh, Hossein Keshavarz and Setareh Mamishi*

DOI: 10.2174/1871526519666190613123217

Open Access Articles

PZQ Therapy: How Close are we in the Development of Effective Alternative Anti-schistosomal Drugs?

, 2019; 19(4): 337 - 349

Raphael Taiwo Aruleba*, Tayo Alex Adekiya, Babatunji Emmanuel Oyinloye, Priscilla Masamba, Londiwe Simphiwe Mbatha, Ashley Pretorius and Abidemi Paul Kappo

Burden of Multidrug Resistant Mycobacterium tuberculosis Among New Cases in Al-Madinah Al-Monawarah, Saudi Arabia

, 2017; 17(1): 14 - 23

Mogahid M. Elhassan, Hassan A. Hemeg, Miskelyemen A. Elmekki, Khalid A. Turkistani and Ahmed A. Abdul-Aziz

Most Cited Articles


Counter-regulatory ‘renin-angiotensin’ system-based candidate drugs to treat COVID-19 diseases in SARS-CoV-2-infected patients

, 2020; 20(4): 407-408.

Cédric ANNWEILER, Zhijian CAO, Yingliang WU, Emmanuelle FAUCON, Stéphanie MOUHAT, Hervé KOVACIC and Jean-Marc SABATIER

DOI: 10.2174/1871526520666200518073329

Case Report

A patient with COVID-19 disease in a referral hospital in Iran: A typical case

, 2020; 20(4): 559-562.

Fereshteh Ghiasvand, Sepideh Zahak Miandoab, Hamid Harandi, Fereshteh Shahmari Golestan and Seyed Ahmad Seyed Alinaghi*

DOI: 10.2174/1871526520666200429115535

Review Article

SARS-CoV-2: The path of prevention and control

, 2021; 21(3): 358-362.

Amal A. Mohamed, Nouran Mohamed, Seham Mohamoud, Fawkia E. Zahran, Rania Abdelmonem Khattab, Dalia Ali El-Damasy, Eman Alsayed and Sherief Abd-Elsalam*

DOI: 10.2174/1871526520666200520112848

Review Article

Albendazole and treatment of hydatid cyst: Review of the literature

, 2019; 19(2): 101-104.

Azar B. Dehkordi, Behnam Sanei, Morteza Yousefi, Seyedeh M. Sharafi, Farhang Safarnezhad, Rasool Jafari and Hossein Y. Darani*

DOI: 10.2174/1871526518666180629134511

Review Article

Hepatitis C virus: Efficacy of new daas regimens

, 2020; 20(2): 143-149.

Amal Ahmed Mohamed, Naglaa El-Toukhy Ramadan El-Toukhy, Ebada Mohamed Said, Hoda Mohamed Rabie Gabal, Hossameldin AbdelAziz, Wahid Doss, Hadeel El-Hanafi, Hala H. El Deeb, Seham Mahmoud, Mahmoud Elkadeem, Hassan Salama Shalby and Sherief Abd-Elsalam*

DOI: 10.2174/1871526519666190121114003

Systematic Review Article

Efficacy of lopinavir/ritonavir compared with standard care for treatment of coronavirus disease 2019 (COVID-19): A systematic review

, August 2021; 21(5): 8-17.

Timotius Ivan Hariyanto, Elizabeth Kristine, Catherine Jillian Hardi and Andree Kurniawan*

DOI: 10.2174/1871526520666201029125725

Review Article

PZQ therapy: How close are we in the development of effective alternative anti-schistosomal drugs?

, 2019; 19(4): 337-349.

Raphael Taiwo Aruleba*, Tayo Alex Adekiya, Babatunji Emmanuel Oyinloye, Priscilla Masamba, Londiwe Simphiwe Mbatha, Ashley Pretorius and Abidemi Paul Kappo

DOI: 10.2174/1871526519666181231153139

Research Article

Synthesis, biological evaluation and molecular docking studies of new pyrazolines as an antitubercular and cytotoxic agents

, 2019; 19(3): 310-321.

Bontha Venkata Subrahmanya Lokesh*, Y. Rajendra Prasad and Afzal Basha Shaik

DOI: 10.2174/1871526519666181217120626

Research Article

High-level aminoglycoside resistance in enterococcus faecalis and enterococcus faecium; as a serious threat in hospitals

, 2020; 20(2): 223-228.

Mahmoud Khodabandeh, Mohsen Mohammadi , Mohammad Reza Abdolsalehi, Meysam Hasannejad-Bibalan , Mehrdad Gholami , Azadeh Alvandimanesh, Abazar Pournajaf and Ramazan Rajabnia*

DOI: 10.2174/1871526519666181130095954

Research Article

Sofosbuvir, pegylated interferon and ribavirin in the treatment of an Egyptian cohort with hepatitis C virus infection in real-life clinical practice

, 2019; 19(2): 179-184.

Sherief Abd-Elsalam*, Rehab Badawi, Sally Elnawasany, Mohamed Yousef, Loai Mansour, Nehad Hawash, Reham A. Elkhouly, Shaimaa Soliman, Amal Selim, Abdelrahman Kobtan and Asem Elfert

DOI: 10.2174/1871526518666180912121835

Most Accessed Articles

Counter-regulatory ‘Renin-Angiotensin’ System-based Candidate Drugs to Treat COVID-19 Diseases in SARS-CoV-2-infected Patients

, 2020; 20(4): 407-408.

Annweiler, Cédric; Cao, Zhijian; Wu, Yingliang; Faucon, Emmanuelle; Mouhat, Stéphanie; Kovacic, Hervé; Sabatier, Jean-Marc

DOI: 10.2174/1871526520666200518073329

SARS-CoV-2: The Path of Prevention and Control

, 2021; 21(3): 358-362.

Mohamed, Amal A.; Mohamed, Nouran; Mohamoud, Seham; Zahran, Fawkia E.; Khattab, Rania Abdelmonem; El-damasy, Dalia Ali; Alsayed, Eman; Abd-Elsalam, Sherief

DOI: 10.2174/1871526520666200520112848

High-Level Aminoglycoside Resistance in Enterococcus Faecalis and Enterococcus Faecium; as a Serious Threat in Hospitals

, 2020; 20(2): 223-228.

Khodabandeh, Mahmoud; Mohammadi, Mohsen; Abdolsalehi, Mohammad Reza; Hasannejad-Bibalan, Meysam; Gholami, Mehrdad; Alvandimanesh, Azadeh; Pournajaf, Abazar; Rajabnia, Ramazan

DOI: 10.2174/1871526519666181130095954

Hepatitis C Virus: Efficacy of New DAAs Regimens

, 2020; 20(2): 143-149.

Mohamed, Amal Ahmed; El-Toukhy, Naglaa El-Toukhy Ramadan; Said, Ebada Mohamed; Gabal, Hoda Mohamed Rabie; AbdelAziz, Hossameldin; Doss, Wahid; El-Hanafi, Hadeel; Deeb, Hala H. El; Mahmoud, Seham; Elkadeem, Mahmoud; Shalby, Hassan Salama; Abd-Elsalam, Sherief

DOI: 10.2174/1871526519666190121114003

A Patient with COVID-19 Disease in a Referral Hospital in Iran: A Typical Case

, 2020; 20(4): 559-562.

Ghiasvand, Fereshteh; Miandoab, Sepideh Zahak; Harandi, Hamid; Golestan, Fereshteh Shahmari; SeyedAlinaghi, SeyedAhmad

DOI: 10.2174/1871526520666200429115535

Comparison of HIV Indicators after the Implementation of a New Model for TB and HIV Management in an Iranian Prison

, 2020; 20(6): 778-783.

Farhoudi, Behnam; SeyedAlinaghi, SeyedAhmad; Ataeinia, Bahar; Hosseini, Mostafa; Jafari, Sirous; Alasvand, Ramin; Tashakoriyan, Mehrzad; Mohraz, Minoo

DOI: 10.2174/1871526519666191015151639

Hand Hygiene Compliance and Effectiveness Against Respiratory Infections Among Hajj Pilgrims: A Systematic Review.

, 2020; 20(3): 273-283.

Alqahtani, Amani S; Fakeerh, Mutaz; Bondagji, Daniah; Park, Silvia; Heywood, Anita E; Wiley, Kerrie E; Booy, Robert; Rashid, Harunor

DOI: 10.2174/1871526518666181001145041

Chloroquine as Chemoprophylaxis for COVID-19: Will This Work.

, 2021; 21(4): 473-474.

Abd-Elsalam, Sherief; Elkadeem, Mahmoud; Glal, Khadija Ahmed

DOI: 10.2174/1871526520666200726224802


Jean-Marc Sabatier
Laboratoire ERT 62 'Ingénierie des peptides à visée thérapeutique'
Université de la Méditerranée
Faculté de Médecine Nord
Boulevard Pierre Dramard
13916 - MARSEILLE, Cedex 20
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