Contents

Drug Metabolism Letters, Volume 8 - Number 1

Editorial

Editorial:

, 8(1): 1

Suresh K. Balani


DOI: 10.2174/187231280801140929153324




Application of a Higher Throughput Approach to Derive Apparent Michaelis-Menten Constants of Isoform-Selective P450-Mediated Biotransformation Reactions in Human Hepatocytes

, 8(1): 2 - 11

Albert P. Li and Kari E. Schlicht


DOI: 10.2174/1872312808666140606101902




Evaluation of Human Hepatocytes Under Prolonged Culture in a Novel Medium for the Maintenance of Hepatic Differentiation: Results with the Model Pro-inflammatory Cytokine Interleukin 6

, 8(1): 12 - 18

Albert P. Li, Qian Yang, Helene Vermet, Nathalie Raoust, Sylvie Klieber and Gerard Fabre


DOI: 10.2174/187231280801140929155351




A Proposed Screening Paradigm for Discovery of Covalent Inhibitor Drugs

, 8(1): 19 - 30

Mehran F. Moghaddam, Yang Tang, Zhihong O’Brien, Samantha J. Richardson, Maria Bacolod, Prasoon Chaturedi, Julius Apuy and Ashutosh Kulkarni


DOI: 10.2174/1872312808666140317151735




Simultaneous Quantitative Determinations of Fluticasone Propionate and Salmeterol Xinafote in Diskus Inhalers

, 8(1): 31 - 35

A. Duran, H. N. Dogan and M. Ulgen


DOI: 10.2174/187231280801140929161136




A New Quaternary Ammonium Cysteine Analogue as a Trapping Reagent for Reactive Metabolites Screening

, 8(1): 36 - 42

Natalia Penner, Xiaojing Liu and Chandra Prakash


DOI: 10.2174/1872312808666140606100739




Comparison of Catalytic Properties of Cytochromes P450 3A4 and 3A5 by Molecular Docking Simulation

, 8(1): 43 - 50

Toshiro Niwa, Motohiro Yasumura, Norie Murayama and Hiroshi Yamazaki


DOI: 10.2174/1872312807666131229121228




Extrahepatic Metabolism may Complicate the IVIVC in Rats

, 8(1): 51 - 66

Massimiliano Fonsi


DOI: 10.2174/187231280801140929160226




Purification of Paraoxonase Enzyme From the Sera of Patients with Behcet’s Disease and Analyzing the Effects of the Drugs Containing Imuran (Azathioprine), Prednisolone (Methylprednisolone) and Colchium (Colchicine)

, 8(1): 67 - 75

Nazan Demir, Hayrunnisa Nadaroglu, Asuman Ozkan, Esen Tasgin, Ceyhun Isik and Yasar Demir


DOI: 10.2174/1872312808666140514113838




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