Contents

Drug Metabolism Letters, Volume 7 - Number 2

Oxidative Stress and Lipid Peroxidation in Prolonged Users of Methamphetamine

, 7(2): 79 - 82

Hassan Solhi, Aliakbar Malekirad, Amir Mohammad Kazemifar and Farzaneh Sharifi


DOI: 10.2174/187231280702140520191324




Inhibition of Major Drug Metabolizing CYPs by Common Herbal Medicines used by HIV/AIDS Patients in Africa– Implications for Herb- Drug Interactions

, 7(2): 83 - 95

Charles Awortwe, Patrick J. Bouic, Collen M. Masimirembwa and Bernd Rosenkranz


DOI: 10.2174/1872312808666140129123210




Preclinical Drug Metabolism and Pharmacokinetics, and Prediction of Human Pharmacokinetics and Efficacious Dose of the Investigational Aurora A Kinase Inhibitor Alisertib (MLN8237)

, 7(2): 96 - 104

Johnny J. Yang, Yu Li, Arijit Chakravarty, Chuang Lu, Cindy Q. Xia, Susan Chen, Sandeep Pusalkar, Mengkun Zhang, Jeffrey Ecsedy, Mark G. Manfredi, Jing-Tao Wu, Wen Chyi Shyu and Suresh K. Balani


DOI: 10.2174/1872312807666131229122359




A Review of Pharmacokinetic Parameters of Metabolites and Prodrugs

, 7(2): 105 - 116

Michel Leandro de Campos, Elias Carvalho Padilha and Rosangela Goncalves Peccinini


DOI: 10.2174/1872312808666140317155008




Culture Duration-, Donor-, and Medium-Dependent Changes in OATP1B3- Mediated Telmisartan Uptake in Human Hepatocytes

, 7(2): 117 - 125

Qing Zhu, Haiyan Xia, Cindy Q. Xia, Qian Yang, Utkarsh Doshi, Albert P. Li and Mingxiang Liao


DOI: 10.2174/1872312808666140317153311




Metabolite Characterization of Anti-cancer Agent Gefitinib in Human Hepatocytes

, 7(2): 126 - 136

Prashant Surve, Selvan Ravindran, Arghya Acharjee, Himanshu Rastogi, Sudipta Basu and Pradnya Honrao


DOI: 10.2174/1872312808666140317154110




The Effect of Pomelo Mix Ethyl Acetate Extract on CYP3A6 and P-Glycoprotein Gene Transcripts in Rabbits

, 7(2): 137 - 140

Yacoub M. Irshaid, Malek A. Zihlef, Suheil M Zmeili, Eman T. Al-Antary, Mais G. Zmaily, Somya N. Al-Embideen and Abdallah O. Amireh


DOI: 10.2174/187231280702140520214901




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