Contents

Drug Metabolism Letters, Volume 6 - Number 2

Cytochrome P450 2A6 Phenotyping Based on Dietary Caffeine Intake in a Japanese Population of Non-smokers

, 6(2): 67 - 72

Miyuki Kimura, Makiko Shimizu, Kazuma Kiyotani, Kazuko Nakagawa, Tetsuya Kamataki and Hiroshi Yamazaki


DOI: 10.2174/1872312811206020067




In Vitro Drug Metabolism of Green Tea Catechins in Human, Monkey, Dog, Rat and Mouse Hepatocytes

, 6(2): 73 - 93

Wendy W. Chen, Geng-Yao Qin, Ting Zhang and Wan-Yong Feng


DOI: 10.2174/1872312811206020073




Limitations of S-Warfarin Truncated Area Under the Concentration-Time Curve to Predict Cytochrome P450 2c9 Activity

, 6(2): 94 - 101

Jerry C. Wu, Anne N. Nafziger, Joseph S. Bertino and Joseph D. Ma


DOI: 10.2174/1872312811206020094




Single-dose Pharmacokinetics and Tolerability of Oral Delta-9- Tetrahydrocannabinol in Patients with Amyotrophic Lateral Sclerosis

, 6(2): 102 - 108

Markus Joerger, Justin Wilkins, Stefania Fagagnini, Reto Baldinger, Rudolf Brenneisen, Ursula Schneider, Bea Goldman and Markus Weber


DOI: 10.2174/1872312811206020102




Sulfation of Buprenorphine, Pentazocine, and Naloxone by Human Cytosolic Sulfotransferases

, 6(2): 109 - 115

Katsuhisa Kurogi, Mei Chen, Yoonjung Lee, Bo Shi, Teng Yan, Ming-Yih Liu, Yoichi Sakakibara, Masahito Suiko and Ming-Cheh Liu


DOI: 10.2174/1872312811206020109




Caffeine Induces CYP1A2 Expression in Rat Hepatocytes but not in Human Hepatocytes

, 6(2): 116 - 119

David Vaynshteyn and Hyunyoung Jeong


DOI: 10.2174/1872312811206020116




Idebenone Treatment Mediates the Effect of Menadione Oxidative Stress Damage in Saccharomyces cerevisiae

, 6(2): 120 - 123

Oliver Gamondi, Sebastian Chapela, Ines Nievas, Isabel Burgos, Manuel Alonso and Carlos Stella


DOI: 10.2174/1872312811206020120




An Improved Synthesis of m-Hydroxymexiletine, a Potent Mexiletine Metabolite

, 6(2): 124 - 128

Alessia Catalano, Alessia Carocci, Giovanni Lentini, Ivana Defrenza, Maria Maddalena Cavalluzzi and Carlo Franchini


DOI: 10.2174/1872312811206020124




The Metabolic Rationale for a Lack of Cross-reactivity Between Sulfonamide Antimicrobials and Other Sulfonamide-containing Drugs

, 6(2): 129 - 133

David F. Lehmann


DOI: 10.2174/1872312811206020129




A Simplified Protocol Employing Elacridar in Rodents: A Screening Model in Drug Discovery to Assess P-gp Mediated Efflux at the Blood Brain Barrier

, 6(2): 134 - 144

Rajareddy Kallem, Chetan P. Kulkarni, Dakshay Patel, Megha Thakur, Michael Sinz, Sheelendra P. Singh, S. Shahe Mahammad and Sandhya Mandlekar


DOI: 10.2174/1872312811206020134




The Pharmacokinetics and Metabolism Study of Sodium 7,4' -oxo-acetic Acid Daidzein in Rat

, 6(2): 145 - 150

Shujun Wang, Ruixue Gao, Kun Xu, Xiaojun Yi, Wei Hou, Chengyu Liu and Fei Cheng


DOI: 10.2174/1872312811206020145




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