Contents

Drug Metabolism Letters, Volume 6 - Number 1

PREFACE

, 6(1): 1

Chandra Prakash


DOI: 10.2174/187231212800229327




Changes of Drug Metabolizing Enzymes in the Liver of Male Sheep Exposed to either Cypermethrin or Dimethoate

, 6(1): 2 - 6

S. A. Sheweita, M. I. Yousef, H. H. Baghdadi and A. G. Elshemy


DOI: 10.2174/187231212800229291




Molecular Analysis and Modeling of Inactivation of Human CYP2D6 by Four Mechanism Based Inactivators

, 6(1): 7 - 14

Mara Livezey, Leslie D. Nagy, Laura E. Diffenderfer, Evan J. Arthur, David J. Hsi, Jeffrey M. Holton and Laura Lowe Furge


DOI: 10.2174/187231212800229318




Comparative Analysis of In Vitro Rat Liver Metabolism of the Antimalarial Primaquine and a Derived Imidazoquine

, 6(1): 15 - 25

Nuno Vale, Iva Fernandes, Rui Moreira, Nuno Mateus and Paula Gomes


DOI: 10.2174/187231212800229273




Loxapine P-glycoprotein Interactions In Vitro

, 6(1): 26 - 32

Andrea Reed, Keith Huie, Elke S. Perloff, James V. Cassella and Lori H. Takahashi


DOI: 10.2174/187231212800229255




Preclinical Metabolism and Pharmacokinetics of SB1317 (TG02), a Potent CDK/JAK2/FLT3 Inhibitor

, 6(1): 33 - 42

Mohammed Khalid Pasha, Ramesh Jayaraman, Venkatesh Pilla Reddy, Pauline Yeo, Evelyn Goh, Anthony Williams, Kee Chuan Goh and Ethirajulu Kantharaj


DOI: 10.2174/187231212800229336




Evaluation of Time-Dependent Cytochrome P450 Inhibition in a High-Throughput, Automated Assay: Introducing a Novel Area Under the Curve Shift Approach

, 6(1): 43 - 53

Sophie Mukadam, Suzanne Tay, Daniel Tran, Leslie Wang, Erlie M. Delarosa, S. Cyrus Khojasteh, Jason S. Halladay and Jane R. Kenny


DOI: 10.2174/187231212800229309




New Insights on Dimethylaminoethanol (DMAE) Features as a Free Radical Scavenger

, 6(1): 54 - 59

Gabriela Malanga, Maria Belen Aguiar, Hugo D. Martinez and Susana Puntarulo


DOI: 10.2174/187231212800229282




Relevance of the Salvage Pathway to N-Hexanoylsphingosine Metabolic Downregulation in Human Neurotumor Cells: Implications for Apoptosis

, 6(1): 60 - 66

Angelo Spinedi


DOI: 10.2174/187231212800229264




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