Contents

Drug Metabolism Letters, Volume 5 - Number 4

Systematic and Pairwise Analysis of the Effects of Aromatic Halogenation and Trifluoromethyl Substitution on Human Liver Microsomal Clearance

, 5(4): 232 - 242

Hao Sun, Christopher E. Keefer and Dennis O. Scott


DOI: 10.2174/187231211798472575




Effect of Oxidative Stress on the Pharmacokinetics of Clomipramine in Rats Treated with Ferric-Nitrilotriacetate

, 5(4): 243 - 252

Shinji Kobuchi, Keizo Fukushima, Hiroaki Aoyama, Tatsuma Matsuda, Yukako Ito, Nobuyuki Sugioka and Kanji Takada


DOI: 10.2174/187231211798472548




A Non-acidic Sulfaphenazole Analog Demonstrating High Intrinsic Clearance and Selectivity by Canine CYP2C21

, 5(4): 253 - 258

Charles W. Locuson, Josh F. Alfaro, Matthew J. Zaya, Denis Billen, Julie A. White and Jeffrey P. Jones


DOI: 10.2174/187231211798472539




A Luminescence Study of the Interaction of Sulfobutylether-β-Cyclodextrin with Rutin

, 5(4): 259 - 266

Min Wu, Zhenghua Song and Jingjing Zhang


DOI: 10.2174/187231211798472520




Toxicophoric and Metabolic In Silico Evaluation of Benzimidazole and Phenylbenzamide Derivatives with Potential Application as Anticancer Agents

, 5(4): 267 - 275

Vinicius Barreto da Silva, Andreia Machado Leopoldino, Carlton Anthony Taft and Carlos Henrique Tomich de Paula da Silva


DOI: 10.2174/187231211798472566




Study of Degradation Behavior of Baicalin during Simulative Blood Sample Processing with Solid Phase Extraction Technology and Identification of the Degradation Product

, 5(4): 276 - 279

Lihong Chen, Qiang Wang and Yuping Tang


DOI: 10.2174/187231211798472502




Investigation of the Metabolism of Rufinamide and Its Interaction with Valproate

, 5(4): 280 - 289

Eric T. Williams, J. Eric Carlson, W. George Lai, Y. Nancy Wong, Tsutomu Yoshimura, David J. Critchley and Milind Narurkar


DOI: 10.2174/187231211798472511




Gender Effects on Rat Metabolism of AMG 900, an Orally Available Small Molecule Aurora Kinase Inhibitor

, 5(4): 290 - 297

Daniel Waldon, Loren Berry, Min-Hwa Jasmine Lin, Laurie Schenkel, L. Steven Hollis and Zhiyang Zhao


DOI: 10.2174/187231211798472557




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