Contents

Drug Metabolism Letters, Volume 5 - Number 1

Effect of Pinocembrin Isolated from Boesenbergia pandurata on Xenobiotic-Metabolizing Enzymes in Rat Liver

, 5(1): 1 - 5

Charatda Punvittayagul, Rawiwan Wongpoomchai, Sirinya Taya and Wilart Pompimon


DOI: 10.2174/187231211794455226




Inhibition of Cytochrome P450 1A2-Mediated Metabolism and Production of Reactive Oxygen Species by Heme Oxygenase-1 in Rat Liver Microsomes

, 5(1): 6 - 16

James R. Reed, George F. Cawley and Wayne L. Backes


DOI: 10.2174/187231211794455253




An In Vitro, High Throughput, Seven CYP Cocktail Inhibition Assay for the Evaluation of New Chemical Entities Using LC-MS/MS

, 5(1): 17 - 24

Jennifer N. Otten, Gary P. Hingorani, Dylan P. Hartley, Scott D. Kragerud and Ronald B. Franklin


DOI: 10.2174/187231211794455235




Mice Brain Nitric Oxide Synthase Response Induced by Anaesthetics and Other Porphyrinogenic Drugs

, 5(1): 25 - 29

Jimena Lavandera, Alcira Batlle and Ana Maria Buzaleh


DOI: 10.2174/187231211794455271




A Comparative Study of the CYP450 Inhibition Potential of Marketed Drugs Using Two Fluorescence Based Assay Platforms Routinely Used in the Pharmaceutical Industry

, 5(1): 30 - 39

Mahmud Kajbaf, Raffaele Longhi, Dino Montanari, Federica Vinco, Monica Rigo, Stefano Fontana and Kevin D. Read


DOI: 10.2174/187231211794455262




Statin Drugs, Metabolic Pathways, and Asthma: A Therapeutic Opportunity Needing Further Research

, 5(1): 40 - 44

Amir A. Zeki, Nicholas J. Kenyon and Tzipora Goldkorn


DOI: 10.2174/187231211794455217




The Metabolism of Methazolamide - Identification of Metabolites in Guinea Pig Urine

, 5(1): 45 - 54

Kenichi Kishida, Norihiro Yamamura, Yoshiaki Iwai, Yoshiteru Sakamoto, Makihiko Kuhara and Tetsuo Sasabe


DOI: 10.2174/187231211794455299




Comparative Pharmacokinetics and Metabolism Studies in Lean and Diet- Induced Obese Mice: An Animal Efficacy Model for 11β -Hydroxysteroid Dehydrogenase Type 1 (11β -HSD1) Inhibitors

, 5(1): 55 - 63

Mengmeng Wang, Xianbin Tian, Louis Leung, Jianyao Wang, Nicole Houvig, Jason Xiang, Eddine Saiah, Seung Hahm, Vipin Suri and Xin Xu


DOI: 10.2174/187231211794455280




Divergent Effects of Nitric Oxide Donors on the Biliary Efflux Transporters in Isolated Perfused Rat Livers: Nitric Oxide-Independent Inhibition of ABC Transporters by Sodium Nitroprusside

, 5(1): 64 - 72

Ridhi Parasrampuria and Reza Mehvar


DOI: 10.2174/187231211794455244




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