Drug Metabolism Letters
Volume 14, 3 Issues, 2020
ISSN: 1874-0758 (Online)
ISSN: 1872-3128 (Print)
This journal supports open access
ISSN: 1874-0758 (Online)
ISSN: 1872-3128 (Print)
This journal supports open access
Contents
Drug Metabolism Letters, Volume 4 - Number 4
A Multi-Endpoint Evaluation of Cytochrome P450 1A2, 2B6 and 3A4 Induction Response in Human Hepatocyte Cultures After Treatment with β - Naphthoflavone, Phenobarbital and Rifampicin
, 4(4): 185 - 194J. G. Zhang, Thuy Ho, Alanna L. Callendrello, Charles L. Crespi and David M. Stresser
DOI: 10.2174/187231210792928224
P-Glycoprotein, but not Multidrug Resistance Protein 4, Plays a Role in the Systemic Clearance of Irinotecan and SN-38 in Mice
, 4(4): 195 - 201Michael Tagen, Yanli Zhuang, Fan Zhang, K. Elaine Harstead, Jun Shen, Paula Schaiquevich, Charles H. Fraga, John C. Panetta, Christopher M. Waters and Clinton F. Stewart
DOI: 10.2174/187231210792928251
P-Glycoprotein and Breast Cancer Resistance Protein Affect Disposition of Tandutinib, A Tyrosine Kinase Inhibitor
, 4(4): 202 - 212Johnny J. Yang, Mark N. Milton, Shaoxia Yu, Mingxiang Liao, Ning Liu, Jing-Tao Wu, Liang-Shang Gan, Suresh K. Balani, Frank W. Lee, Shimoga Prakash and Cindy Q. Xia
DOI: 10.2174/187231210792928279
Contribution of Three CYP3A Isoforms to Metabolism of R- and S-Warfarin
, 4(4): 213 - 219Drew R. Jones, So-Young Kim, Gunnar Boysen, Chul-Ho Yun and Grover P. Miller
DOI: 10.2174/187231210792928242
Reversible Covalent Binding of Neratinib to Human Serum Albumin In Vitro
, 4(4): 220 - 227Appavu Chandrasekaran, Li Shen, Susan Lockhead, Aram Oganesian, Jianyao Wang and JoAnn Scatina
DOI: 10.2174/187231210792928206
Daunorubicin Metabolism in Leukemic Cells Isolated from Patients with Acute Myeloid Leukemia
, 4(4): 228 - 232Alex Bogason, Michele Masquelier, Pierre Lafolie, Cristine Skogastierna, Christer Paul, Astrid Gruber and Sigurd Vitols
DOI: 10.2174/187231210792928260
In Vitro Screening of Metabolic Clearance Using Two Concentration Points
, 4(4): 233 - 240Eric T. Williams, Nadia Farah, Robert D. Pelletier and W. George Lai
DOI: 10.2174/187231210792928288
Comparative Efflux of Saquinavir, Ritonavir and Lopinavir from Primary Human Cells
, 4(4): 241 - 245Bilge Diker, Omar Janneh, Rolf P.G. van Heeswijk and Karen F.T. Copeland
DOI: 10.2174/187231210792928297
Co-Expression of Recombinant Human CYP2C9 with Human Cytochrome P450 Reductase in Protease Deficient S. cerevisiae Strain at a Higher Scale Yields an Enzyme of Higher Specific Activity
, 4(4): 246 - 253K. N. Purnachandra Rao, Sunil Kumar Suman, Y. Ravi Kiran, Arup Ranjan Kuanr, Anuj Kumar Gupta, Kunal Bhalla, Vipul Kumar, Prabuddha Kundu, Kajal Arora and Rajeev Soni
DOI: 10.2174/187231210792928233
Two Branched Polar Groups and Polar Linker Moieties of Thiophene Amide Derivatives Are Essential for MRP2/ABCC2 Recognition
, 4(4): 254 - 261Yiding Hu, Kathleen E. Sampson, Li Xing, Na Li, Bruce R. Heyde, Jin Xie and Yurong Lai
DOI: 10.2174/187231210792928215
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Editor-in-Chief
Zhiyang Zhao
Alliance Pharma
Malvern, PA
USA
Biography
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Alliance Pharma
Malvern, PA
USA
Biography
Biography of Zhiyang Zhao
Zhiyang Zhao received his Ph.D. degree in Medicinal Chemistry from Virginia Tech, Blacksburg, Virginia, USA. Dr. Zhao’s biopharmaceutical/pharmaceutical work experience encompasses over 25 years of research in metabolic and pharmacokinetic properties of compounds for drug discovery and development at Pfizer, GlaxoSmithKline and Amgen. Currently, Dr. Zhao serve as Chief Scientific Officer (CSO) at Alliance Pharma, Inc. and appointed as an adjunct professor at the School of Pharmacy, the University of North Carolina at Chapel Hill. Dr. Zhao has published over 50 peer reviewed original research papers and patents in the areas of new drug targets, drug metabolism, pharmacokinetics, and toxicology.
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Drug Metabolism Letters was launched in 2007. Dr. Zhiyang Zhao serves as the Editor-in-Chief of the journal.
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