Contents

Drug Metabolism Letters, Volume 3 - Number 1

Molecular Analysis of the In Vivo Metabolism and Biodistribution of Metabolically and Non-Metabolically Activated Combi-Molecules of the Triazene Class

, 3(1): 1 - 9

Qiyu Qiu, Anne-Laure Larroque, Bernard Gibbs, Youqiang Fang, Younes Lakhrissi, Jean-Paul Soucy, Shadreck Mzengeza, Zakaria Rachid and Bertrand J. Jean-Claude


DOI: 10.2174/187231209787176344




O-Demethylation of Dextromethorphan Using Microbial Cultures

, 3(1): 10 - 14

Samathoti Prasanthi, Maravajhala Vidyavathi, Koganti V.S.R.G. Prasad and Devarakonda Rama Krishna


DOI: 10.2174/187231209787176326




Impact of Cerebral Malaria on Brain Distribution of Mefloquine

, 3(1): 15 - 17

Sylvie Barraud de Lagerie, Christine Fernandez, Michele German-Fattal, Jean-Charles Gantier, Francois Gimenez and Robert Farinotti


DOI: 10.2174/187231209787176407




Utility of Nicotiana tabacum Cell Suspension Cultures Expressing Human CYP1A1, CYP1A2 and CYP3A4 to Study the Oxidative Metabolism of the Herbicide 14C-Fluometuron

, 3(1): 18 - 27

Maren Anne Breuer, Burkhard Schmidt and Ingolf Schuphan


DOI: 10.2174/187231209787176335




Structure-Activity Relationship (SAR): Effort Towards Blocking NGlucuronidation of Indazoles (PF-03376056) By Human UGT1A Enzymes

, 3(1): 28 - 34

Kelly Rose, Young-Sun Yang, Richard Sciotti and Hongliang Cai


DOI: 10.2174/187231209787176371




Copper (II) Complexes of [1,2,4]Triazolo [1,5-a]Pyrimidine Derivatives as Potential Anti-Parasitic Agents

, 3(1): 35 - 44

Samira Boutaleb-Charki, Clotilde Marin, Carmen R. Maldonado, Maria J. Rosales, Jesus Urbano, Ramon Guitierrez-Sanchez, Miguel Quiros, Juan M. Salas and Manuel Sanchez-Moreno


DOI: 10.2174/187231209787176317




Impact of Time-Dependent Inactivation on the Estimation of Enzyme Kinetic Parameters for Midazolam

, 3(1): 45 - 53

Craig Giragossian, Jennifer LaPerle, Rachel E. Kosa and Sarah Gillian


DOI: 10.2174/187231209787176353




Study of Efficacy of Reactivator HI-6 in Reactivation of Immobilized Acetylcholinesterase, Inhibited by Organophosphorus Chemical Warfare Agents of the “G” Series

, 3(1): 54 - 57

Monika Hoskovcova, Emil Halamek and Zbynek Kobliha


DOI: 10.2174/187231209787176380




Inhibitory Effect of Codeine on Sucrase Activity

, 3(1): 58 - 60

Dariush Minai-Tehrani, Saeed Minoui, Marzie Sepehre, Zohre Sharif-Khodai and Tooka Aavani


DOI: 10.2174/187231209787176362




Co-Induction of CYP3A12 and 3A26 in Dog Liver Slices by Xenobiotics: Species Difference Between Human and Dog CYP3A Induction

, 3(1): 61 - 66

Jun Chen, Cindy Tran, Li Xiao, Jairam Palamanda, Thomas Klapmuts, Pramila Kumari, Xinjie Lin, Er-jia Wang, Yi-Zhong Gu, Mary Humphries, Annette S. Uss and K.-C. Cheng


DOI: 10.2174/187231209787176399




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