Drug Metabolism Letters, Volume 2 - Number 3


, 2(3): 151 - 152

Chandra Prakash

DOI: 10.2174/187231208785425836

Oxidative Bioactivation and Toxicity of Leflunomide in Immortalized Human Hepatocytes and Kinetics of the Non-Enzymatic to Its Major etabolitie, A77 1726

, 2(3): 153 - 157

Quee Ming Seah, Lee-Sun New, Eric C.Y. Chan and Urs A. Boeslsterli

DOI: 10.2174/187231208785425791

Microsome Biocolloids for Rapid Drug Metabolism and in hibition Assessment by LC-MS

, 2(3): 158 - 162

Besnik Bajrami, Sadagopan Krishnan and James F. Rusling

DOI: 10.2174/187231208785425854

Effects of Cyclosporine A and Itraconazole on Permeability, Biliary Excretion and Pharmacokinetics of Amlidipine

, 2(3): 163 - 168

Liang Ni, Xue Yu, Qiaoling Yu, Xijing Chen and Lee Jia

DOI: 10.2174/187231208785425782

Quantitative Relationship Between Rifampicin Exposure and Induction of CYP3a11 in SXR Humanized Mice: Extrapolation to Human CYP3A4 Induction Potential

, 2(3): 169 - 175

Sean Kim, Devin Pray, Ming Zheng, Danial G. Morgan, Jenifer G. Pizzano, Mary E. Zoeckler, Anjaneya Chimalakonda and Michael W. Sinz

DOI: 10.2174/187231208785425809

Aldehyde Oxidase Activity and Inhibition in Hepatocytes and Cytosolic Fraction from Mouse, Rat,Monkey and Human

, 2(3): 176 - 183

Jasminder Sahi, Kishore K. Khan and Chris B. Black

DOI: 10.2174/187231208785425818

Troglitazone Thiol Adduct Formation in Human Liver Microsomes: Enzyme Knietics and Reaction Phenotyping

, 2(3): 184 - 189

Jinping Gan, Qinling Qu, Bing He, Wen C. Shyu, A. David Rodrigues and Kan He

DOI: 10.2174/187231208785425773

Effects of Enzyme Sources on Midazolam 1-Hydroxylation Activity Catalyzed by Recombinant Cytochrome P450 3A4 in Combination with NADPH-Cytochrome P450 Reductase

, 2(3): 190 - 192

Chie Emoto, Norie Murayama and Hiroshi Yamazaki

DOI: 10.2174/187231208785425737

Proposed New Addition to 3Rs for Ethical and Humane Use of Rats in Pharmacokinetic Studies – ‘Recycle’

, 2(3): 193 - 197

Suresh K. Balani, Chaung Lu, Kym Cardoza, Cicely Berg, Ji Zhang and Frank W. Lee

DOI: 10.2174/187231208785425827

Allosteric Modulation of SULT2A1 by Celecoxib and Nimesulide: Computational Analyses

, 2(3): 198 - 204

Emine Bihter Yalcin, Scott M. Struzik and Roberta S. King

DOI: 10.2174/187231208785425755

Assessment of Cytochrome P450 Induction in Human Hepatocytes Using the Cocktail Strategy Plus Liquid Chromatography Tandem Mass Spectrometry

, 2(3): 205 - 209

Agustin Lahoz, Maria Teresa Donato, Laura Picazo, Jose V. Castell and Maria Jose Gomez-Lechon

DOI: 10.2174/187231208785425845

Absolute Quantification of Human Uridine-Diphosphate Glucuronosyl Transferase (UGT) Enzyme Isoforms 1A1 and 1A6 By Tandem LC-MS

, 2(3): 210 - 222

John K. Fallon, David E. Harbourt, Saber H. Maleki, Fay K. Kessler, Joseph K. Ritter and Philip C. Smith

DOI: 10.2174/187231208785425764

Role of P-glycoprotein in the Transport of Tanshinone I, One Active Triterpenoid from Salvia miltiorrhiza

, 2(3): 223 - 230

Xing-Xiao Li, Zhi-Wei Zhou and Shu-Feng Zhou

DOI: 10.2174/187231208785425746

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