Contents

Drug Metabolism Letters, Volume 2 - Number 1

Visualization of First-Pass Drug Metabolism of Terfenadine by MALDIImaging Mass Spectrometry

, 2(1): 1 - 4

Yunsheng Hsieh, Jiwen Chen, Ian Knemeyer, Lee Crossman and Walter A. Korfmacher


DOI: 10.2174/187231208783478461




Phenotyping of Cytochrome P450 3A Enzyme in Gujarat Population

, 2(1): 5 - 10

Ashutosh J. Jani, Shivprakash Rathnam and Anita A. Mehta


DOI: 10.2174/187231208783478416




Renal and Hepatic Transporter Expression in Type 2 Diabetic Rats

, 2(1): 11 - 17

Jose E. Manautou, Michael T. Nowicki, Lauren M. Aleksunes, Sharmilee P. Sawant, Ankur V. Dnyanmote and Harihara M. Mehendale


DOI: 10.2174/187231208783478425




Allelic Variations in 5, 10-Methylenetetrahydrofolate Reductase Gene and Susceptibility to Cervical Cancer in Indian Women

, 2(1): 18 - 22

Samar Husain Naqvi, Naveen Kumar Nandan, Saima Wajid, Shilpie Biswas, Sominder Singh Juneja, Moshahid Rizvi and Raminder Prakash


DOI: 10.2174/187231208783478498




Pharmacokinetics of Ceftriaxone in Carbontetrachloride-Induced Hepatopathic and Uranyl nitrate-Induced Nephropathic Goats Following Single Dose Intravenous Administration

, 2(1): 23 - 28

Tapan Kumar Mandal, Tapas Kumar Sar, Shymal Kumar Das and Animesh Kumar Chakraborty


DOI: 10.2174/187231208783478515




Modulation of Porcine (Sus scrofa domestica) and Pheasant (Phasianus colchicus) Carbonyl Reducing Enzymes by Anthelmintic Therapy with Flubendazole

, 2(1): 29 - 34

Barbora Szotakova, Milan Nobilis, Jiri Lamka, Veronika Krizova, Michal Savlik and Lenka Skalova


DOI: 10.2174/187231208783478452




Identification of a Novel Glutathione Conjugate of Diclofenac by LTQOrbitrap

, 2(1): 35 - 40

Yohannes Teffera, Daniel J. Waldon, Adria E. Colletti, Brian K. Albrecht and Zhiyang Zhao


DOI: 10.2174/187231208783478506




Rapid and Sensitive Characterization of the Metabolite Formation Enzyme Kinetics of Radiolabeled Drugs Using Stop-Flow Liquid Radiochromatography

, 2(1): 41 - 46

Lifei Wang, Weiping Zhao, Donglu Zhang and Mingshe Zhu


DOI: 10.2174/187231208783478470




Time and Dose Dependent Study of Doxorubicin Induced DU-145 Cytotoxicity

, 2(1): 47 - 50

Saeed S. Al-Ghamdi


DOI: 10.2174/187231208783478443




An Examination of IC50 and IC50-Shift Experiments in Assessing Time-Dependent Inhibition of CYP3A4, CYP2D6 and CYP2C9 in Human Liver Microsomes

, 2(1): 51 - 59

Loren M. Berry and Zhiyang Zhao


DOI: 10.2174/187231208783478407




Induction of Cytochrome P450 3A by the Ginkgo biloba Extract and Bilobalides in Human and Rat Primary Hepatocytes

, 2(1): 60 - 66

Shu-Feng Zhou, Ying Deng, Hui-chang Bi, Li-zi Zhao, Xue-ding Wang, Jie Chen, Zhi-min Ou, Liang Ding, Le-jia Xu, Su Guan, Xiao Chen and Min Huang


DOI: 10.2174/187231208783478489




Investigations Into the Drug-Drug Interaction Potential of Tapentadol in Human Liver Microsomes and Fresh Human Hepatocytes

, 2(1): 67 - 75

Christa Kneip, Rolf Terlinden, Horst Beier and Genfu Chen


DOI: 10.2174/187231208783478434




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