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Drug Metabolism Letters

Volume 14, 3 Issues, 2021
ISSN: 1874-0758 (Online)
ISSN: 1872-3128 (Print)
This journal supports open access


Drug Metabolism Letters, Volume 11 - Number 2

Review Article

Therapeutic Potentials and Cytochrome P450-Mediated Interactions Involving Herbal Products Indicated for Diabetes Mellitus

, 11(2): 74 - 85

Cyprian O. Onyeji*, Sharon I. Igbinoba and Gbola Olayiwola

DOI: 10.2174/1872312811666171121104431

Research Article

Analysis of Elevated Levels of Nandrolone Decanoate Induced Cytochrome- P450 Alterations in Mice

, 11(2): 86 - 92

Parmita Chowdhury* and Rita Mahanta

DOI: 10.2174/1872312811666171114145535

Research Article

A Pharmacokinetic-Pharmacodynamic Model of Tamoxifen and Endoxifen to Predict Their Distribution and Effects on Inhibition of Tumor Growth

, 11(2): 93 - 101

Shengyue Yuan, Qingrong Sun, Yao Chen and Jun Liao*

DOI: 10.2174/1872312811666170815160751

Research Article

Investigation of Ocular Bioactivation Potential and the Role of Cytochrome P450 2D Enzymes in Rat

, 11(2): 102 - 110

Jennifer L. Dumouchel*, Upendra A. Argikar, Jaimie Spear, Ann Brown, Christine E. Dunne, Valerie M. Kramlinger, Amanda L. Cirello and Mithat Gunduz

DOI: 10.2174/1872312811666170911122919

Research Article

The Effects of Drug Metabolizing Enzyme Inhibitors on Hepatic Efflux and Uptake Transporters

, 11(2): 111 - 118

Jonathan Cheong, Jason S. Halladay, Emile Plise, Jasleen K. Sodhi and Laurent Salphati*

DOI: 10.2174/1872312811666171010101248

Research Article

Selective Suppression of CYP3A4 mRNA and Enzyme Activity by Epidermal Growth Factor in Plated Human Hepatocytes

, 11(2): 119 - 127

J. George Zhang*, Duan Wang, Thuy Ho, Robert J. Clark and David M. Stresser

DOI: 10.2174/1872312811666171128141105

Research Article

Transactivation Assays that Identify Indirect and Direct Activators of Human Pregnane X Receptor (PXR, NR1I2) and Constitutive Androstane Receptor (CAR, NR1I3)

, 11(2): 128 - 137

Marija Pinne*, Elsa Ponce and Judy L. Raucy

DOI: 10.2174/1872312812666171207113639

Research Article

Evaluation of Farnesoid X Receptor Target Gene Induction in Human Hepatocytes: Amino Acid Conjugation

, 11(2): 138 - 143

Jean Simmermacher* and Michael Sinz

DOI: 10.2174/1872312812666171227213946


Genotoxicity of 4-(piperazin-1-yl)-8-(trifluoromethyl)pyrido[2,3-e][1,2,4] triazolo[4,3-a]pyrazine, a Potent H4 Receptor Antagonist for the Treatment of Allergy: Evidence of Glyoxal Intermediate Involvement

, 11(2): 144 - 148

Mithat Gunduz*, Amanda L. Cirello, Peter Klimko, Jennifer L. Dumouchel and Upendra A. Argikar

DOI: 10.2174/1872312811666171106151730


Zhiyang Zhao
Alliance Pharma
Malvern, PA
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Journal History

Drug Metabolism Letters was launched in 2007. Dr. Zhiyang Zhao serves as the Editor-in-Chief of the journal.

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