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Drug Metabolism Letters

Volume 14, 3 Issues, 2020
ISSN: 1874-0758 (Online)
ISSN: 1872-3128 (Print)
This journal supports open access

In the current pandemic scenario, publication process of all articles related to Coronavirus will be expedited, for timely publication of much needed research


Drug Metabolism Letters, Volume 11 - Number 2

Review Article

Therapeutic Potentials and Cytochrome P450-Mediated Interactions Involving Herbal Products Indicated for Diabetes Mellitus

, 11(2): 74 - 85

Cyprian O. Onyeji*, Sharon I. Igbinoba and Gbola Olayiwola

DOI: 10.2174/1872312811666171121104431

Research Article

Analysis of Elevated Levels of Nandrolone Decanoate Induced Cytochrome- P450 Alterations in Mice

, 11(2): 86 - 92

Parmita Chowdhury* and Rita Mahanta

DOI: 10.2174/1872312811666171114145535

Research Article

A Pharmacokinetic-Pharmacodynamic Model of Tamoxifen and Endoxifen to Predict Their Distribution and Effects on Inhibition of Tumor Growth

, 11(2): 93 - 101

Shengyue Yuan, Qingrong Sun, Yao Chen and Jun Liao*

DOI: 10.2174/1872312811666170815160751

Research Article

Investigation of Ocular Bioactivation Potential and the Role of Cytochrome P450 2D Enzymes in Rat

, 11(2): 102 - 110

Jennifer L. Dumouchel*, Upendra A. Argikar, Jaimie Spear, Ann Brown, Christine E. Dunne, Valerie M. Kramlinger, Amanda L. Cirello and Mithat Gunduz

DOI: 10.2174/1872312811666170911122919

Research Article

The Effects of Drug Metabolizing Enzyme Inhibitors on Hepatic Efflux and Uptake Transporters

, 11(2): 111 - 118

Jonathan Cheong, Jason S. Halladay, Emile Plise, Jasleen K. Sodhi and Laurent Salphati*

DOI: 10.2174/1872312811666171010101248

Research Article

Selective Suppression of CYP3A4 mRNA and Enzyme Activity by Epidermal Growth Factor in Plated Human Hepatocytes

, 11(2): 119 - 127

J. George Zhang*, Duan Wang, Thuy Ho, Robert J. Clark and David M. Stresser

DOI: 10.2174/1872312811666171128141105

Research Article

Transactivation Assays that Identify Indirect and Direct Activators of Human Pregnane X Receptor (PXR, NR1I2) and Constitutive Androstane Receptor (CAR, NR1I3)

, 11(2): 128 - 137

Marija Pinne*, Elsa Ponce and Judy L. Raucy

DOI: 10.2174/1872312812666171207113639

Research Article

Evaluation of Farnesoid X Receptor Target Gene Induction in Human Hepatocytes: Amino Acid Conjugation

, 11(2): 138 - 143

Jean Simmermacher* and Michael Sinz

DOI: 10.2174/1872312812666171227213946


Genotoxicity of 4-(piperazin-1-yl)-8-(trifluoromethyl)pyrido[2,3-e][1,2,4] triazolo[4,3-a]pyrazine, a Potent H4 Receptor Antagonist for the Treatment of Allergy: Evidence of Glyoxal Intermediate Involvement

, 11(2): 144 - 148

Mithat Gunduz*, Amanda L. Cirello, Peter Klimko, Jennifer L. Dumouchel and Upendra A. Argikar

DOI: 10.2174/1872312811666171106151730


Zhiyang Zhao
Alliance Pharma
Malvern, PA

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COPE Compliant

Journal History

Drug Metabolism Letters was launched in 2007. Dr. Zhiyang Zhao serves as the Editor-in-Chief of the journal.
Scopus CiteScore Metrics: 1.01


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