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Contents

Drug Metabolism Letters, Volume 10 - Number 4


Research Article

Pharmacokinetics, Metabolism and Disposition of [14C]XQ-1H After Intravenous Administration to Male Rats

, 10(4): 228 - 239

Yinlin Qin, Tao Chen, Qiu Jin, Kai Guo, Hao Feng, Dennis Heller and Zhe-ming Gu


DOI: 10.2174/1872312811666170118162931



Research Article

Cytochrome P450 2A6 Phenotyping Using Dietary Caffeine Salivary Metabolite Ratios and Genotyping Using Blood on Storage Cards in Non-smoking Japanese Volunteers

, 10(4): 240 - 243

Norie Murayama, Makiko Shimizu, Kenta Kobayashi, Izumi Kishimoto and Hiroshi Yamazaki


DOI: 10.2174/1872312810666161114144008



Research Article

Strong Induction of Cytochrome P450 1A/3A, But not P450 2B, in Cultured Hepatocytes from Common Marmosets and Cynomolgus Monkeys by Typical Human P450 Inducing Agents

, 10(4): 244 - 253

Shotaro Uehara, Yasuhiro Uno, Takako Suzuki, Takashi Inoue, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki


DOI: 10.2174/1872312810666161114144412



Research Article

Genipin Inhibits the Induction of Inducible Nitric Oxide Synthase Through the Inhibition of NF-κB Activation in Rat Hepatocytes

, 10(4): 254 - 263

Richi Nakatake, Takumi Tsuda, Takashi Matsuura, Hirokazu Miki, Hidehiko Hishikawa, Hideyuki Matsushima, Morihiko Ishizaki, Kosuke Matsui, Masaki Kaibori, Mikio Nishizawa, Tadayoshi Okumura and Masanori Kon


DOI: 10.2174/1872312810666161020164658



Research Article

A Novel Liquid Chromatography Tandem Mass Spectrometry Method for the Estimation of Bilirubin Glucuronides and its Application to In Vitro Enzyme Assays

, 10(4): 264 - 269

Siva P. Putluru, Murali K. Matta, Deepak Ahire, Murali Subramanian, Michael Sinz and Sandhya Mandlekar


DOI: 10.2174/1872312810666161124143522



Research Article

Ortho-Methylarylamines as Time-Dependent Inhibitors of Cytochrome P450 1A1 Enzyme

, 10(4): 270 - 277

Jayalakshmi Sridhar, Jiawang Liu, Rajesh Komati, Richard Schroeder, Quan Jiang, Phan Tram, Kevin Riley and Maryam Foroozesh


DOI: 10.2174/1872312810666161220155226



Research Article

Variability of Zaleplon 5-Oxidase Activity in Mice and Humans, and Inhibition by Raloxifene

, 10(4): 278 - 285

Chiaki Tanoue, Kazumi Sugihara, Yoshitaka Tayama, Naoto Uramaru, Yoko Watanabe, Shigeru Ohta and Shigeyuki Kitamura


DOI: 10.2174/1872312810666161227145358



Research Article

Quantification of Etodolac in Human Plasma for Pharmacokinetics and Bioequivalence Studies in 27 Korean Subjects

, 10(4): 286 - 294

Il-Dong Song, Ju-Seop Kang, Hyun-Jin Kim, Se-Mi Kim, Dong-Xu Zhao, Shin-Hee Kim, Min-Young Chun and Kyu-Hyun Lee


DOI: 10.2174/1872312811666170116151004



Research Article

The Metabolism of Methazolamide in Immortalized Human Keratinocytes, HaCaT Cells

, 10(4): 295 - 305

Tetsuo Sasabe, Shinichiro Maeda, Kenichi Kishida, Mariko Yamano, Yoshihiro Miwa and Toshihiro Sugiyama


DOI: 10.2174/1872312811666170127160931





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