Contents
Drug Metabolism Letters, Volume 10 - Number 4
Biography
Research Article
Pharmacokinetics, Metabolism and Disposition of [14C]XQ-1H After Intravenous Administration to Male Rats
, 10(4): 228 - 239Yinlin Qin, Tao Chen, Qiu Jin, Kai Guo, Hao Feng, Dennis Heller and Zhe-ming Gu
DOI: 10.2174/1872312811666170118162931
Research Article
Cytochrome P450 2A6 Phenotyping Using Dietary Caffeine Salivary Metabolite Ratios and Genotyping Using Blood on Storage Cards in Non-smoking Japanese Volunteers
, 10(4): 240 - 243Norie Murayama, Makiko Shimizu, Kenta Kobayashi, Izumi Kishimoto and Hiroshi Yamazaki
DOI: 10.2174/1872312810666161114144008
Research Article
Strong Induction of Cytochrome P450 1A/3A, But not P450 2B, in Cultured Hepatocytes from Common Marmosets and Cynomolgus Monkeys by Typical Human P450 Inducing Agents
, 10(4): 244 - 253Shotaro Uehara, Yasuhiro Uno, Takako Suzuki, Takashi Inoue, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
DOI: 10.2174/1872312810666161114144412
Research Article
Genipin Inhibits the Induction of Inducible Nitric Oxide Synthase Through the Inhibition of NF-κB Activation in Rat Hepatocytes
, 10(4): 254 - 263Richi Nakatake, Takumi Tsuda, Takashi Matsuura, Hirokazu Miki, Hidehiko Hishikawa, Hideyuki Matsushima, Morihiko Ishizaki, Kosuke Matsui, Masaki Kaibori, Mikio Nishizawa, Tadayoshi Okumura and Masanori Kon
DOI: 10.2174/1872312810666161020164658
Research Article
A Novel Liquid Chromatography Tandem Mass Spectrometry Method for the Estimation of Bilirubin Glucuronides and its Application to In Vitro Enzyme Assays
, 10(4): 264 - 269Siva P. Putluru, Murali K. Matta, Deepak Ahire, Murali Subramanian, Michael Sinz and Sandhya Mandlekar
DOI: 10.2174/1872312810666161124143522
Research Article
Ortho-Methylarylamines as Time-Dependent Inhibitors of Cytochrome P450 1A1 Enzyme
, 10(4): 270 - 277Jayalakshmi Sridhar, Jiawang Liu, Rajesh Komati, Richard Schroeder, Quan Jiang, Phan Tram, Kevin Riley and Maryam Foroozesh
DOI: 10.2174/1872312810666161220155226
Research Article
Variability of Zaleplon 5-Oxidase Activity in Mice and Humans, and Inhibition by Raloxifene
, 10(4): 278 - 285Chiaki Tanoue, Kazumi Sugihara, Yoshitaka Tayama, Naoto Uramaru, Yoko Watanabe, Shigeru Ohta and Shigeyuki Kitamura
DOI: 10.2174/1872312810666161227145358
Research Article
Quantification of Etodolac in Human Plasma for Pharmacokinetics and Bioequivalence Studies in 27 Korean Subjects
, 10(4): 286 - 294Il-Dong Song, Ju-Seop Kang, Hyun-Jin Kim, Se-Mi Kim, Dong-Xu Zhao, Shin-Hee Kim, Min-Young Chun and Kyu-Hyun Lee
DOI: 10.2174/1872312811666170116151004
Research Article
The Metabolism of Methazolamide in Immortalized Human Keratinocytes, HaCaT Cells
, 10(4): 295 - 305Tetsuo Sasabe, Shinichiro Maeda, Kenichi Kishida, Mariko Yamano, Yoshihiro Miwa and Toshihiro Sugiyama
DOI: 10.2174/1872312811666170127160931
Acknowledgement
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