Contents
Drug Metabolism Letters, Volume 10 - Number 3
Editorial
Research Article
New Screening Criteria Setting on Evaluation of Cytochrome P450 Induction Using HepaRG Cells with Multiplex Branched DNA Technologies in Early Drug Discovery
, 10(3): 152 - 160Akira Ogasawara, Nao Torimoto, Naoki Tsuda, Fumika Aohara, Rikiya Ohashi, Yasuhiro Yamada and Hideki Taniguchi
DOI: 10.2174/1872312810666160822110011
New Screening Criteria Setting on Evaluation of Cytochrome P450 Induction Using HepaRG Cells with Multiplex Branched DNA Technologies in Early Drug Discovery
Research Article
Intracellular Retention of Three Quinuclidine Derivatives in Caco-2 Permeation Experiments: Mechanisms and Impact on Estimating Permeability and Active Efflux Ratio
, 10(3): 161 - 171Hong Jin, Sudarshan Kapadnis, Ting Chen, Dooyoung Lee, Andrew McRiner, Andrew Cook, Duane A. Burnett, Gerhard Koenig and Cuyue Tang
DOI: 10.2174/1872312810666160725123322
Intracellular Retention of Three Quinuclidine Derivatives in Caco-2 Permeation Experiments: Mechanisms and Impact on Estimating Permeability and Active Efflux Ratio
Research Article
Application of a “Fit for Purpose” PBPK Model to Investigate the CYP3A4 Induction Potential of Enzalutamide
, 10(3): 172 - 179Rangaraj Narayanan, Matthew Hoffmann, Gondi Kumar and Sekhar Surapaneni
DOI: 10.2174/1872312810666160729124745
Application of a “Fit for Purpose” PBPK Model to Investigate the CYP3A4 Induction Potential of Enzalutamide
Research Article
An Investigation of Sodium Fusidate and Recombinant Cytochrome P450 Enzymes Inhibition In-Vitro
, 10(3): 180 - 186John Mishriky, Jacqueline Balassone, Zenah Bashour, Simranjit Kaur, Vini Raman, Robel Getachew, Narin Osman, Daniel Guidone, Vincent Chan and Peter J. Little
DOI: 10.2174/1872312810666160607015045
An Investigation of Sodium Fusidate and Recombinant Cytochrome P450 Enzymes Inhibition In-Vitro
Research Article
Inhibition of Procarcinogen Activating Enzyme CYP1A2 Activity and Free Radical Formation by Caffeic Acid and its Amide Analogues
, 10(3): 187 - 194Paitoon Narongchai, Kanokporn Niwatananun, Siripun Narongchai, Winthana Kusirisin and Churdsak Jaikang
DOI: 10.2174/1872312810666160608123113
Inhibition of Procarcinogen Activating Enzyme CYP1A2 Activity and Free Radical Formation by Caffeic Acid and its Amide Analogues
Research Article
The Uremic Toxin Indoxyl-3-Sulfate Induces CYP1A2 In Primary Human Hepatocytes
, 10(3): 195 - 199Hong Liu, Rangaraj Narayanan, Matthew Hoffmann and Sekhar Surapaneni
DOI: 10.2174/1872312810666160719143703
The Uremic Toxin Indoxyl-3-Sulfate Induces CYP1A2 In Primary Human Hepatocytes
Research Article
Identification and Characterization of the Human Cytosolic Sulfotransferases Mediating the Sulfation of Clioquinol and Iodoquinol
, 10(3): 200 - 205Akihiro Yamamoto, Maame Debrah-Pinamang, Nicholas J. DiModica, Katsuhisa Kurogi, Ali A. Naqvi, Ying Hui, Yoichi Sakakibara, Masahito Suiko and Ming-Cheh Liu
DOI: 10.2174/1872312810666160719142850
Identification and Characterization of the Human Cytosolic Sulfotransferases Mediating the Sulfation of Clioquinol and Iodoquinol
Research Article
UHPLC Quantitation Method for New Thiazolidinedione LPSF/GQ-02 and In Vitro/In Vivo Kinetic Studies
, 10(3): 206 - 212Carla Monalizi Vieira, Michel Leandro de Campos, Elias Carvalho Padilha, Marina Pitta, Ivan da Rocha Pitta, Maria do Carmo Alves de Lima and Rosângela Gonçalves Peccinini
DOI: 10.2174/1872312810666160725124554
UHPLC Quantitation Method for New Thiazolidinedione LPSF/GQ-02 and In Vitro/In Vivo Kinetic Studies
Research Article
CYP2B6 and OPRM1 Receptor Polymorphisms at Methadone Clinics And Novel OPRM1 Haplotypes: A Cross-Sectional Study
, 10(3): 213 - 218Ahmad Abdulrahman AlMeman, Rusli Ismail and Markus Perola
DOI: 10.2174/1872312810666160810104040
CYP2B6 and OPRM1 Receptor Polymorphisms at Methadone Clinics And Novel OPRM1 Haplotypes: A Cross-Sectional Study
Research Article
Effect of Cardiovascular Injury on Catabolism of Adenosine and Adenosine 5-‘Triphosphate in Systemic Blood in a Freely Moving Rat Model In Vivo
, 10(3): 219 - 226Pollen K. Yeung, Shyam S. Kolathuru and Remigius U. Agu
DOI: 10.2174/1872312810666160607013859
Effect of Cardiovascular Injury on Catabolism of Adenosine and Adenosine 5-‘Triphosphate in Systemic Blood in a Freely Moving Rat Model In Vivo
Webmaster Contact: info@benthamscience.org