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Drug Metabolism Letters

Volume 14, 3 Issues, 2021
ISSN: 1874-0758 (Online)
ISSN: 1872-3128 (Print)
This journal supports open access


Drug Metabolism Letters, Volume 10 - Number 2

The Effects of Statin Therapy on the Human Airway

, 10(2): 75 - 82

Lorraine Thong, John MacSharry and Desmond M. Murphy

DOI: 10.2174/1872312810666160303112012

Efficiency in Drug Discovery: Liver S9 Fraction Assay As a Screen for Metabolic Stability

, 10(2): 83 - 90

Samantha J. Richardson, April Bai, Ashutosh A. Kulkarni and Mehran F. Moghaddam

DOI: 10.2174/1872312810666160223121836

Rate-Determining and Rate-Limiting Steps in the Clearance and Excretion of a Potent and Selective p21-Activated Kinase Inhibitor: A Case Study of Rapid Hepatic Uptake and Slow Elimination in Rat

, 10(2): 91 - 100

Peter W. Fan, Jacob Z. Chen, M. Allan Jaochico, Hank La, Ning Liu, Teresa Mulder, Robert T. Cass, Matthew Durk, Kirsten Messick, Nicole Valle, Shannon Liu, Wendy Lee, James J. Crawford, Joachim Rudolf, Lesley J. Murray, S. Cyrus Khojasteh and Matthew Wright

DOI: 10.2174/1872312810666160411144358

In Vitro Study of UGT Metabolism and Permeability of Orientin and Isoorientin, Two Active flavonoid C-glycosides

, 10(2): 101 - 110

Jian Shi, Lijun Zhu, Ye Li, Haihui Zheng, Jia Yu, Linlin Lu and Zhongqiu Liu

DOI: 10.2174/1872312810666160219121217

Biotransformation of Cobicistat: Metabolic Pathways and Enzymes

, 10(2): 111 - 123

Pengcheng Wang, Amina I. Shehu, Ke Liu, Jie Lu and Xiaochao Ma

DOI: 10.2174/1872312810666160303112212

In Vitro CYP2D Inhibitory Effect and Influence on Pharmacokinetics and Pharmacodynamic Parameters of Metoprolol Succinate by Terminalia arjuna in Rats

, 10(2): 124 - 135

Alice Varghese, Jay Savai, Shruti Mistry, Preeti Khandare, Kalyani Barve, Nancy Pandita and Ram Gaud

DOI: 10.2174/1872312810666160219121415

Elucidating the Mechanism of Tofacitinib Oxidative Decyanation

, 10(2): 136 - 143

Hoa Le, Peter W. Fan, Susan Wong, Shuguang Ma, James P. Driscoll, Cornelis E.C.A. Hop and S. Cyrus Khojasteh

DOI: 10.2174/1872312810666160427104954

Formation of A Novel Purine Metabolite through CYP3A4 Bioactivation and Glutathione Conjugation

, 10(2): 144 - 150

Julius L. Apuy, Cathie Xiang, Sarah Franc, Sayee G. Hegde, Robert Hubbard, Jingjing Zhao and Mehran F. Moghaddam

DOI: 10.2174/1872312810666160511150558


Zhiyang Zhao
Alliance Pharma
Malvern, PA
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Journal History

Drug Metabolism Letters was launched in 2007. Dr. Zhiyang Zhao serves as the Editor-in-Chief of the journal.

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