Contents

Drug Metabolism Letters, Volume 1 - Number 3

Antioxidants Suppress Th1-Type Immune Response In Vitro

, 1(3): 166 - 171

Katharina Schroecksnadel, Birgit Fischer, Harald Schennach, Guenter Weiss and Dietmar Fuchs


DOI: 10.2174/187231207781369816




Effect of Neurotransmitters on NADPH-Cytochrome P450 Reductase In Vitro Activity

, 1(3): 172 - 175

Guillermo Gervasini, Carmen Martinez, Julio Benitez and Jose A.G. Agundez


DOI: 10.2174/187231207781369762




cAMP-Mediated Regulation of CYP Enzymes and Its Application in Chemotherapy

, 1(3): 176 - 178

Yoshihiro Ishikawa, Sayaka Suzuki, Koji Otsu, Coskun Ulucan, Kousaku Iwatsubo and Haruki Eguchi


DOI: 10.2174/187231207781369744




Application of In-Line Liquid Chromatography-Accurate Radioisotope Counting-Mass Spectrometry (LC-ARC-MS) to Evaluate Metabolic Profile of [3H]-Mefenamic Acid in Rat Plasma

, 1(3): 179 - 188

Wing Lam, Cho-Ming Loi, James Atherton, Wayne Stolle, John Easter and Abdul Mutlib


DOI: 10.2174/187231207781369771




PET-Evaluated Transport of [11C]Hydroxyurea Across the Rat Blood-Brain Barrier - Lack of Influence of Cyclosporin and Probenecid

, 1(3): 189 - 194

Stina Syvanen, Julien Barletta, Gunnar Blomquist, Bengt Langstrom and Mats Bergstrom


DOI: 10.2174/187231207781369799




An Indirect Screen for Brain Uptake of 1,2-Diarylethane Melanocortin 4 Receptor Antagonists in Rats

, 1(3): 195 - 198

Wei Yin, Liang-Shang Gan, Jing-Tao Wu, Suresh K. Balani, Hua Yang and Frank W. Lee


DOI: 10.2174/187231207781369753




Effect of Recombinant Human Thymosin-α1, an Immuno-Modulating Peptide with 28 Amino Acids, on the Activity of Cytochrome P450s

, 1(3): 199 - 204

Bing Wang, Fan He, Yu Lin, Min Huang and Shu-Feng Zhou


DOI: 10.2174/187231207781369825




Involvement of P-glycoprotein and Multidrug Resistance Associated Protein 1 in the Transport of Tanshinone IIB, a Primary Active Diterpenoid Quinone from the Roots of Salvia miltiorrhiza, Across the Blood-Brain Barrier

, 1(3): 205 - 217

Zhi-Wei Zhou, Xiao Chen, Jun Liang, Xi-Yong Yu, Jing-Yuan Wen and Shu-Feng Zhou


DOI: 10.2174/187231207781369807




Effects of Various Promoter Derived Sequences on the Cleavage Kinetic of an Hammerhead Ribozyme Directed Against Cyclin E1 mRNA

, 1(3): 218 - 225

Johannes Platz, Mario Grassi, Anne Kuhn, Reinhard Kandolf, Giorgia Racchi, Rossella Farra, Barbara Dapas, Andrea Pascotto, Carlo Giansante, Nicola Fiotti, Gianfranco Guarnieri and Gabriele Grassi


DOI: 10.2174/187231207781369726




Application of Liquid Chromatography-Accelerator Mass Spectrometry (LC-AMS) to Evaluate the Metabolic Profiles of a Drug Candidate in Human Urine and Plasma

, 1(3): 226 - 231

Chandra Prakash, Christopher L. Shaffer, Larry M. Tremaine, Rosa G. Liberman, Paul L. Skipper, Jimmy Flarakos and Steven R. Tannenbaum


DOI: 10.2174/187231207781369735




Studies of Bioactivity, Conformation and Pharmacokinetic Profiles of Site-Specific PEGylated Thymosin Alpha 1 Derivatives

, 1(3): 232 - 340

Jiankun Qie, Jinbo Ma, Liangyou Wang, Xiaoyu Xu, Jianquan Zheng, Sijian Dong, Jianwei Xie, Huixian Sun, Wenxia Zhou, Chunhui Qi, Xiunan Zhao, Yongxiang Zhang and Keliang Liu


DOI: 10.2174/187231207781369780




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