Contents
Drug Metabolism Letters, Volume 1 - Number 2
Peroxynitrite Induces Apoptosis and Decline in Intracellular Free Mg with Concomitant Elevation in [Ca2+]i in Rat Aortic Smooth Muscle Cells:Possible Roles of Extracellular and Intracellular Magnesium Ions in Peroxynitrite-Induced Cell Death
, 1(2): 85 - 89Jianfeng Li, Wenyan Li, Weimin Liu, Bella T. Altura and Burton M. Altura
DOI: 10.2174/187231207780363651
An Estimate of the Number of Hepatocyte Donors Required to Provide Reasonable Estimates of Human Hepatic Clearance from In Vitro Experiments
, 1(2): 91 - 95James Byers, Kenneth Bachmann, Heather Eng, Anand Katta, Donald White, Ritwik Ghosh, Nicola J. Hewitt, Paul Silber and Genfu Chen
DOI: 10.2174/187231207780363660
Involvement of Cytochromes P450 2D6, 2B6 and 2C19 in the Metabolism of (-)-Deprenyl and N-Methyl,N-propargylphenylethylamine
, 1(2): 97 - 100K. A. Rittenbach and G. B. Baker
DOI: 10.2174/187231207780363589
A Glucuronidation Pathway of Capecitabine Occurs in Rats but Not in Mice and Humans
, 1(2): 101 - 107F. Desmoulin, C. Claparols, D. Bon, G. Larrieu, R. Martino and M. Malet-Martino
DOI: 10.2174/187231207780363615
Assessment of Cryopreserved Hepatocytes as an Alternative to Fresh Hepatocytes forComparative InterspeciesMetabolism Studieswith Suitable Acceptance Criteria
, 1(2): 109 - 120Ziqiang (Zack) Cheng, Christine E. Herron, Gary Bowers and Mark de Serres
DOI: 10.2174/187231207780363624
The Human Sperm Glutathione System: A Key Role in Male Fertility and Successful Cryopreservation
, 1(2): 121 - 126Marcos Meseguer, Jose Antonio Martinez-Conejero, Lourdes Muriel, Antonio Pellicer, Jose Remohi and Nicolas Garrido
DOI: 10.2174/187231207780363633
Application of Simple Mathematical Expressions to Relate Half-Lives of Drugs in Mice to Those in Humans
, 1(2): 127 - 129Kenneth Bachmann, Jonathan Chupka, Paul Erhardt and Donald White
DOI: 10.2174/187231207780363606
Intracellular Delivery of Nanogel-Quantum Dot Hybrid Nanoparticles into Human Periodontal Ligament Cells
, 1(2): 131 - 135Tomoe Fukui, Hiroaki Kobayashi, Urara Hasegawa, Toshiyuki Nagasawa, Kazunari Akiyoshi and Isao Ishikawa
DOI: 10.2174/187231207780363570
Resin-Salve from Norway Spruce - A Potential Method to Treat Infected Chronic Skin Ulcers?
, 1(2): 143 - 145Arno Sipponen, Merja Rautio, Janne J. Jokinen, Tapio Laakso, Pekka Saranpaa and Jouni Lohi
DOI: 10.2174/187231207780363598
The Utility of Stable Cell Lines to Assess Species Differences in PXR Transactivation
, 1(2): 147 - 152Michael W. Sinz, Devin Pray and Judy Raucy
DOI: 10.2174/187231207780363561
Disposition of Vorinostat, A Novel Histone Deacetylase Inhibitor and Anticancer Agent, in Preclinical Species
, 1(2): 153 - 161Punam Sandhu, Paul A. Andrews, Maribeth P. Baker, Kenneth A. Koeplinger, Eric D. Soli, Thomas Miller and Thomas A. Baillie
DOI: 10.2174/187231207780363642
Frequency of CYP1A2 Polymorphism in Beagle Dogs
, 1(2): 163 - 165Valerie J. Whiterock, Terrye A. Delmonte, Lester E. Hui, Tami L. Orcutt and Michael W. Sinz
DOI: 10.2174/187231207780363688
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