Contents

Drug Metabolism Letters, Volume 1 - Number 1

EDITORIAL

, 1(1): 1

Chandra Prakash


DOI: 10.2174/187231207779814346




Effect of Common NAT2 Variant Alleles in the Acetylation of the Major Clonazepam Metabolite, 7-minoclonazepam

, 1(1): 3 - 5

M. Olivera, C. Martinez, G. Gervasini, J. A. Carrillo, S. Ramos, J. Benitez, E. Garcia-Martin and J. A. G. Agundez


DOI: 10.2174/187231207779814283




Verapamil, but not Probenecid, Co-Administration Can Convert Desloratadine to a Sedating Antihistamine in Mice

, 1(1): 7 - 11

Anand Katta, Mugunthu Dhananjeyan, Crystal Bykowski, Paul Erhardt, Miles Hacker, Donald B. White and Kenneth Bachmann


DOI: 10.2174/187231207779814391




In Vitro Inhibition of Rat CYP1A1 and CYP1A2 by Piceatannol, a Hydroxylated Metabolite of trans-Resveratrol

, 1(1): 13 - 16

Thomas K. H. Chang, Jie Chen and Chia-Ting Yu


DOI: 10.2174/187231207779814337




Comparison of Paraben Stability in Human and Rat Skin

, 1(1): 17 - 21

Heather M. Harville, Richard Voorman and Jeffery J. Prusakiewicz


DOI: 10.2174/187231207779814300




ABCB1, SLCO1B1 and UGT1A1 Gene Polymorphisms Are Associated with Toxicity Line Irinotecan

, 1(1): 23 - 30

Katrin E. Rhodes, Wu Zhang, Dongyun Yang, Oliver A. Press, Michael Gordon, Daniel Vallbohmer, Anne M. Schultheis, Georg Lurje, Robert D. Ladner, William Fazzone, Heinz-Josef Lenz and Syma Iqbal


DOI: 10.2174/187231207779814328




Prioritization of Clinical Drug Interaction Studies Using In Vitro Cytochrome P450 Data:“Rank Order” Approach

, 1(1): 31 - 35

A. David Rodrigues


DOI: 10.2174/187231207779814247




Drug Confinement and Delivery in Ceramic Implants

, 1(1): 37 - 40

Maria Vallet-Regi, Francisco Balas, Montserrat Colilla and Miguel Manzano


DOI: 10.2174/187231207779814382




Application of Pharmacogenomics in Drug Discovery and Development:Correlations Between Transcriptional Modulation and Preclinical Safety Observations

, 1(1): 41 - 48

Lilian G. Yengi, Qian Xiang, Li Shen, Appavu Chandrasekaran, John Kao and JoAnn Scatina


DOI: 10.2174/187231207779814274




A Role for Lysosomal Phospholipase A2 in Drug Induced Phospholipidosis

, 1(1): 49 - 53

Akira Abe, Miki Hiraoka and James A. Shayman


DOI: 10.2174/187231207779814292




Folate Nutrigenetics: A Convergence of Dietary Folate Metabolism, Folic Acid Supplementation, and Folate Antagonist Pharmacogenetics

, 1(1): 55 - 60

Brian Meshkin and Kenneth Blum


DOI: 10.2174/187231207779814319




A Unique Example of Drug Metabolism: Tetra- and Penta-Oxygenation Reactions of Capravirine in Rats, Dogs and Humans

, 1(1): 61 - 65

Hai-Zhi Bu, William F. Pool, Ellen Y. Wu and Bhasker V. Shetty


DOI: 10.2174/187231207779814373




Metabolic Stability Screen for Drug Discovery Using Cassette Analysis and Column Switching

, 1(1): 67 - 72

Jason S. Halladay, Susan Wong, Sharmin M. Jaffer, Achintya K. Sinhababu and S. Cyrus Khojasteh-Bakht


DOI: 10.2174/187231207779814364




Structures of Various Cytochromes c Evaluated from the Redox Behaviors Using the Optically Active Co(III) Complex-Modified Au Electrode

, 1(1): 73 - 75

Isao Takahashi, Chika Nishijima, Tomohiko Inomata, Yasuhiro Funahashi, Tomohiro Ozawa and Hideki Masuda


DOI: 10.2174/187231207779814265




Effects of Propofol Analogs on Glucuronidation of Propofol, an Anesthetic Drug, by Human Liver Microsomes

, 1(1): 77 - 79

Makiko Shimizu, Yoshiaki Matsumoto and Hiroshi Yamazaki


DOI: 10.2174/187231207779814355




Drug Interactions of Tipranavir, a New HIV Protease Inhibitor

, 1(1): 81 - 84

Judit Morello, Sonia Rodriguez-Novoa, Inmaculada Jimenez-Nacher and Vincent Soriano


DOI: 10.2174/187231207779814256




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