Open Access Articles

Transactivation Assays that Identify Indirect and Direct Activators of Human Pregnane X Receptor (PXR, NR1I2) and Constitutive Androstane Receptor (CAR, NR1I3)

, 2017; 11(2): 128 - 137

Marija Pinne*, Elsa Ponce and Judy L. Raucy

The Metabolism of Methazolamide in Immortalized Human Keratinocytes, HaCaT Cells

, 2016; 10(4): 295 - 305

Tetsuo Sasabe*, Shinichiro Maeda, Kenichi Kishida, Mariko Yamano, Yoshihiro Miwa and Toshihiro Sugiyama

Rate-Determining and Rate-Limiting Steps in the Clearance and Excretion of a Potent and Selective p21-Activated Kinase Inhibitor: A Case Study of Rapid Hepatic Uptake and Slow Elimination in Rat

, 2016; 10(2): 91 - 100

Peter W. Fan, Jacob Z. Chen, M. Allan Jaochico, Hank La, Ning Liu, Teresa Mulder, Robert T. Cass, Matthew Durk, Kirsten Messick, Nicole Valle, Shannon Liu, Wendy Lee, James J. Crawford, Joachim Rudolf, Lesley J. Murray, S. Cyrus Khojasteh and Matthew Wright

Efficiency in Drug Discovery: Liver S9 Fraction Assay As a Screen for Metabolic Stability

, 2016; 10(2): 83 - 90

Samantha J. Richardson, April Bai, Ashutosh A. Kulkarni and Mehran F. Moghaddam

Commentary: A Myriad Aberrations on Information of Ontogeny of Drug Metabolizing Enzymes in the Pediatric Population: An Obstacle for Personalizing Drug Therapy in the Pediatric Population

, 2016; 10(2): 72 - 74

Chakradhara Rao S. Uppugunduri and Marc Ansari

Formation of A Novel Purine Metabolite through CYP3A4 Bioactivation and Glutathione Conjugation

, 2016; 10(2): 144 - 150

Julius L. Apuy, Cathie Xiang, Sarah Franc, Sayee G. Hegde, Robert Hubbard, Jingjing Zhao and Mehran F. Moghaddam

Impact of Cytochrome P450 2C19*2 and *3 on Clopidogrel Loading Dose in Saudi Patients with Acute Coronary Syndrome

, 2016; 10(1): 65 - 70

Hassan Khalaf, Ahmad AbdulRahman Al Meman and Seemab Rasool

Influence of ABCB1 Gene Polymorphisms and P-Glycoprotein Activity on Cyclosporine Pharmacokinetics in Peripheral Blood Mononuclear Cells in Healthy Volunteers

, 2008; 2(2): 76 - 82

Nicolas Ansermot, Michela Rebsamen, Jocelyne Chabert, Marc Fathi, Marianne Gex-Fabry, Youssef Daali, Marie Besson, Michel Rossier, Serge Rudaz, Denis Hochstrasser, Pierre Dayer and Jules Desmeules

Long Term Treatment with Tetradecylthioacetic Acid Improves the Antioxidant Status in Obese Zucker (fa/fa) Rats

, 2008; 2(2): 138 - 145

Hege Wergedahl, Kjetil Berge, Pavol Bohov, Karl-Johan Tronstad, Lise Madsen and Rolf K. Berge

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