Most Cited Articles

Evaluation of time-dependent cytochrome P450 inhibition in a high-throughput, automated assay: Introducing a novel area under the curve shift approach

, 2012; 6(1): 43-53

Mukadam S., Tay S., Tran D., Wang L., Delarosa E.M., Khojasteh S.C., Halladay J.S., Kenny J.R.

DOI: 10.2174/187231212800229309

An improved synthesis of m-Hydroxymexiletine, a potent mexiletine metabolite

, 2012; 6(2): 124-128

Catalano A., Carocci A., Lentini G., Defrenza I., Cavalluzzi M.M., Franchini C.

DOI: 10.2174/1872312811206020124

A simplified protocol employing elacridar in rodents: A screening model in drug discovery to assess P-gp mediated efflux at the blood brain barrier

, 2012; 6(2): 134-144

Kallem R., Kulkarni C.P., Patel D., Thakur M., Sinz M., Singh S.P., Mahammad S.S., Mandlekar S.

DOI: 10.2174/1872312811206020134

Stereospecific synthesis of m-Hydroxymexiletine enantiomers

, 2012; 6(3): 182-186

Catalano A., Carocci A., Lentini G., Defrenza I., Bruno C., Franchini C.

DOI: 10.2174/1872312811206030005

Development of Flavone Propargyl Ethers as Potent and Selective Inhibitors of Cytochrome P450 Enzymes 1A1 and 1A2

, 2013; 6(4): 275-284

Sridhar J., Ellis J., Dupart P., Liu J., Stevens C.L., Foroozesh M.

DOI: 10.2174/1872312811206040007

Sulfation of buprenorphine, pentazocine, and naloxone by Human Cytosolic Sulfotransferases

, 2012; 6(2): 109-115

Kurogi K., Chen M., Lee Y., Shi B., Yan T., Liu M.-Y., Sakakibara Y., Suiko M., Liu M.-C.

DOI: 10.2174/1872312811206020109

Metabolism of r-and s-warfarin by cyp2c19 into four hydroxywarfarins

, 2012; 6(3): 157-164

Kim S.-Y., Kang J.-Y., Hartman J.H., Park S.-H., Jones D.R., Yun C.-H., Boysen G., Miller G.P.

DOI: 10.2174/1872312811206030002

Inhibition of hepatobiliary transporters by a novel kinase inhibitor contributes to hepatotoxicity in beagle dogs

, 2013; 7(1): 15-22

Daniels J.S., Lai Y., South S., Chiang P.-C., Walker D., Feng B., Mireles R., Whiteley L.O., Mckenzie J.W., Stevens J., Mourey R., Anderson D., Davis Jr.J.W.

DOI: 10.2174/18723128112066660018

The Evaluation of CYP2B6 Inhibition by Artemisinin Antimalarials in Recombinant Enzymes and Human Liver Microsomes

, 2013; 6(4): 247-257

Ericsson T., Masimirembwa C., Abelo A., Ashton M.

DOI: 10.2174/1872312811206040004

Comparative analysis of in vitro rat liver metabolism of the antimalarial primaquine and a derived imidazoquine

, 2012; 6(1): 15-25

Vale N., Fernandes I., Moreira R., Mateus N., Gomes P.

DOI: 10.2174/187231212800229273

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