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Cytochrome P450 3A4 Induction: Lumacaftor versus Ivacaftor Potentially Resulting in Significantly Reduced Plasma Concentration of Ivacaftor

, 2018; 12(1): 71-74.

Elena K. Schneider*


DOI: 10.2174/1872312812666180328105259



Cytochrome P450 1A2 Messenger RNA is a More Reliable Marker than Cytochrome P450 1A2 Activity, Phenacetin O-Deethylation, for Assessment of Induction Potential of Drug-Metabolizing Enzymes Using HepaRG Cells

, 2018; 12(1): 14-23.

Akira Ogasawara*, Nozomu Kato, Nao Torimoto, Fumika Aohara, Rikiya Ohashi, Yasuhiro Yamada and Hideki Taniguchi


DOI: 10.2174/1872312812666180119114013



Drug Metabolite Generation Using a Laboratory Evolved NADPH Independent Cytochrome P450: Application of in vitro and in silico Approaches

, 2013; 7(1): 68-77.

Nyaradzo T. L. Chigorimbo-Murefu, Mathew Njoroge, Stefan Louw, Grace Mugumbate and Kelly Chibale


DOI: 10.2174/18723128112069990014



Characterization of Liver- and Cancer-type-Organic Anion Transporting Polypeptide (OATP) 1B3 Messenger RNA Expression in Normal and Cancerous Human Tissues

, 2018; 12(1): 24-32.

Khondoker Alam, Taleah Farasyn, Kai Ding and Wei Yue*


DOI: 10.2174/1872312812666180326110146




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