Most Accessed Articles


The Effects of Drug Metabolizing Enzyme Inhibitors on Hepatic Efflux and Uptake Transporters

, 2017; 11(2): 111-118.

Jonathan Cheong, Jason S. Halladay, Emile Plise, Jasleen K. Sodhi and Laurent Salphati*


DOI: 10.2174/1872312811666171010101248



Investigation of Ocular Bioactivation Potential and the Role of Cytochrome P450 2D Enzymes in Rat

, 2017; 11(2): 102-110.

Jennifer L. Dumouchel*, Upendra A. Argikar, Jaimie Spear, Ann Brown, Christine E. Dunne, Valerie M. Kramlinger, Amanda L. Cirello and Mithat Gunduz


DOI: 10.2174/1872312811666170911122919



Evaluation of Farnesoid X Receptor Target Gene Induction in Human Hepatocytes: Amino Acid Conjugation

, 2017; 11(2): 138-143.

Jean Simmermacher* and Michael Sinz


DOI: 10.2174/1872312812666171227213946



A Pharmacokinetic-Pharmacodynamic Model of Tamoxifen and Endoxifen to Predict Their Distribution and Effects on Inhibition of Tumor Growth

, 2017; 11(2): 93-101.

Shengyue Yuan, Qingrong Sun, Yao Chen and Jun Liao*


DOI: 10.2174/1872312811666170815160751




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