Most Accessed Articles


Utility of Pooled Cryopreserved Human Enterocytes as an In vitro Model for Assessing Intestinal Clearance and Drug-Drug Interactions

, 2018; 12(1): 3-13.

Susan Wong, Utkarsh Doshi, Peter Vuong, Ning Liu, Suzanne Tay, Hoa Le, Mika Kosaka, Jane R. Kenny, Albert P. Li and Zhengyin Yan*


DOI: 10.2174/1872312812666171213114422



Drug Metabolite Generation Using a Laboratory Evolved NADPH Independent Cytochrome P450: Application of in vitro and in silico Approaches

, 2013; 7(1): 68-77.

Nyaradzo T. L. Chigorimbo-Murefu, Mathew Njoroge, Stefan Louw, Grace Mugumbate and Kelly Chibale


DOI: 10.2174/18723128112069990014



The Effects of Drug Metabolizing Enzyme Inhibitors on Hepatic Efflux and Uptake Transporters

, 2017; 11(2): 111-118.

Jonathan Cheong, Jason S. Halladay, Emile Plise, Jasleen K. Sodhi and Laurent Salphati*


DOI: 10.2174/1872312811666171010101248



In vitro Drug Metabolism Investigation of 7-Ethoxycoumarin in Human, Monkey, Dog and Rat Hepatocytes by High Resolution LC-MS/MS

, 2018; 12(1): 33-53.

Wan-Yong Feng*, Jenny Wen and Kathe Stauber


DOI: 10.2174/1872312812666180418142056




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