Most Accessed Articles

Mixed Matrix Method Provides A Reliable Metabolite Exposure Comparison for Assessment of Metabolites in Safety Testing (MIST)

, 2017; 11(1): 21-28.

Ryan H. Takahashi, Cyrus Khojasteh, Matthew Wright, Cornelis E.C.A. Hop and Shuguang Ma*


DOI: 10.2174/1872312811666170710193229


A Novel Liquid Chromatography Tandem Mass Spectrometry Method for the Estimation of Bilirubin Glucuronides and its Application to In Vitro Enzyme Assays

, 2016; 10(4): 264-269.

Siva P. Putluru*, Murali K. Matta, Deepak Ahire, Murali Subramanian, Michael Sinz and Sandhya Mandlekar


DOI: 10.2174/1872312810666161124143522


The Uremic Toxin Indoxyl-3-Sulfate Induces CYP1A2 In Primary Human Hepatocytes

, 2016; 10(3): 195-199.

Hong Liu, Rangaraj Narayanan, Matthew Hoffmann and Sekhar Surapaneni


DOI: 10.2174/1872312810666160719143703


Efficiency in Drug Discovery: Liver S9 Fraction Assay As a Screen for Metabolic Stability

, 2016; 10(2): 83-90.

Samantha J. Richardson, April Bai, Ashutosh A. Kulkarni and Mehran F. Moghaddam


DOI: 10.2174/1872312810666160223121836


The Role of Placental Carbonyl Reducing Enzymes in Biotransformation of Bupropion and 4-methylnitrosamino-1-(3-pyridyl)-1-butanone

, 2017; 11(1): 29-34.

Valentina M. Fokina, Svetlana L. Patrikeeva, Cheryl Oncken, Gary D.V. Hankins, Mahmoud S. Ahmed and Tatiana Nanovskaya*


DOI: 10.2174/1872312811666170607095202


CYP2B6 and OPRM1 Receptor Polymorphisms at Methadone Clinics And Novel OPRM1 Haplotypes: A Cross-Sectional Study

, 2016; 10(3): 213-218.

Ahmad Abdulrahman AlMeman, Rusli Ismail and Markus Perola


DOI: 10.2174/1872312810666160810104040


Comparison of Catalytic Properties of Cytochromes P450 3A4 and 3A5 by Molecular Docking Simulation

, 2014; 8(1): 43-50.

Toshiro Niwa, Motohiro Yasumura, Norie Murayama and Hiroshi Yamazaki


DOI: 10.2174/1872312807666131229121228


Intracellular Retention of Three Quinuclidine Derivatives in Caco-2 Permeation Experiments: Mechanisms and Impact on Estimating Permeability and Active Efflux Ratio

, 2016; 10(3): 161-171.

Hong Jin, Sudarshan Kapadnis, Ting Chen, Dooyoung Lee, Andrew McRiner, Andrew Cook, Duane A. Burnett, Gerhard Koenig and Cuyue Tang


DOI: 10.2174/1872312810666160725123322


Potential Minor Haplotypes of CYP2D6 in the Japanese Population

, 2017; 11(1): 53-59.

Masatoshi Masuda*, Tsutomu Fujiwara, Masayuki Matsunaga and Takehisa Matsumaru


DOI: 10.2174/1872312811666170613080221


Identification and Characterization of the Human Cytosolic Sulfotransferases Mediating the Sulfation of Clioquinol and Iodoquinol

, 2016; 10(3): 200-205.

Akihiro Yamamoto, Maame Debrah-Pinamang, Nicholas J. DiModica, Katsuhisa Kurogi, Ali A. Naqvi, Ying Hui, Yoichi Sakakibara, Masahito Suiko and Ming-Cheh Liu


DOI: 10.2174/1872312810666160719142850


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