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Drug Metabolism Letters
Continued as:
Drug Metabolism and Bioanalysis Letters
Volume 15, 3 Issues, 2022
ISSN: 1874-0758 (Online)
ISSN: 1872-3128 (Print)
This journal supports open access
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Editor's Choice
The Role of Aldehyde Oxidase in the Metabolic Clearance of Substituted Benzothiazoles
, 2021;
14
(
2
):
126
- 136
Yohannes Teffera*, Jingzhou Liu, Paul Krolikowski and Zhiyang Zhao
DOI:
10.2174/1872312814666210405101419
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Carbon-carbon Bond Cleavage Catalyzed by Human Cytochrome P450 Enzymes: α-ketol as the Key Intermediate Metabolite in Sequential Metabolism of Olanexidine
, 2021;
14
(
1
):
41
- 53
Yiding Hu*, Yi Xiao, Zhesui Rao, Vasant Kumar, Hanlan Liu and Chuang Lu
DOI:
10.2174/1872312813666191125095818
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A Practical Perspective on the Evaluation of Small Molecule CNS Penetration in Drug Discovery
, 2019;
13
(
2
):
78
- 94
Liyue Huang*, Mary C. Wells and Zhiyang Zhao
DOI:
10.2174/1872312813666190311125652
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Unequal Absorption of Radiolabeled and Nonradiolabeled Drug from the Oral Dose Leads to Incorrect Estimates of Drug Absorption and Circulating Metabolites in a Mass Balance Study
, 2019;
13
(
1
):
37
- 44
Ryan H. Takahashi*, Jae H. Chang, Jodie Pang, Xiaorong Liang and Shuguang Ma
DOI:
10.2174/1872312813666181129162237
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New Perspectives on Acyl Glucuronide Risk Assessment in Drug Discovery: Investigation of In vitro Stability, In situ Reactivity, and Bioactivation
, 2018;
12
(
2
):
84
- 92
Mithat Gunduz*, Upendra A. Argikar, Amanda L. Cirello and Jennifer L. Dumouchel
DOI:
10.2174/1872312812666180611113656
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Characterization of Liver- and Cancer-type-Organic Anion Transporting Polypeptide (OATP) 1B3 Messenger RNA Expression in Normal and Cancerous Human Tissues
, 2018;
12
(
1
):
24
- 32
Khondoker Alam, Taleah Farasyn, Kai Ding and Wei Yue*
DOI:
10.2174/1872312812666180326110146
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Genotoxicity of 4-(piperazin-1-yl)-8-(trifluoromethyl)pyrido[2,3-e][1,2,4] triazolo[4,3-a]pyrazine, a Potent H4 Receptor Antagonist for the Treatment of Allergy: Evidence of Glyoxal Intermediate Involvement
, 2017;
11
(
2
):
144
- 148
Mithat Gunduz*, Amanda L. Cirello, Peter Klimko, Jennifer L. Dumouchel and Upendra A. Argikar
DOI:
10.2174/1872312811666171106151730
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Mixed Matrix Method Provides A Reliable Metabolite Exposure Comparison for Assessment of Metabolites in Safety Testing (MIST)
, 2017;
11
(
1
):
21
- 28
Ryan H. Takahashi, Cyrus Khojasteh, Matthew Wright, Cornelis E.C.A. Hop and Shuguang Ma*
DOI:
10.2174/1872312811666170710193229
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A Novel Plated Hepatocyte Relay Assay (PHRA) for In Vitro Evaluation of Hepatic Metabolic Clearance of Slowly Metabolized Compounds
, 2016;
10
(
1
):
3
- 15
Chi-Chi Peng, Utkarsh Doshi, Chandra Prakash and Albert P. Li
DOI:
10.2174/1872312809666150818111500
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Adverse Drug Events in Children: How Big is the Problem?
, 2015;
9
(
2
):
109
- 110
Peter J. Zed
DOI:
10.2174/1872312809666150904182455
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Human HepaRG Cells can be Cultured in Hanging-drop Plates for Cytochrome P450 Induction and Function Assays
, 2015;
9
(
1
):
3
- 7
Norie Murayama, Takashi Usui, Nicky Slawny, Christophe Chesne and Hiroshi Yamazaki
DOI:
10.2174/1872312809666150119104806
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Direct and Rapid Transcript Analysis Assay for CYP mRNA Expression and Inducibility in Human Primary Hepatocytes
, 2014;
8
(
2
):
77
- 87
Laura Mattinen, Jenni Kublbeck, Oona Rechardt, Paavo Honkakoski and Jari Rautio
DOI:
10.2174/1872312808666140606101422
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Comparison of Catalytic Properties of Cytochromes P450 3A4 and 3A5 by Molecular Docking Simulation
, 2014;
8
(
1
):
43
- 50
Toshiro Niwa, Motohiro Yasumura, Norie Murayama and Hiroshi Yamazaki
DOI:
10.2174/1872312807666131229121228
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