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(Pharmacokinetics and Metabolism Laboratory, College of Pharmacy and Department of Medicine, Faculties of Health Professions and Medicine, Dalhousie University, Halifax, NS, )

Drug Metabolism Letters


Volume 11


Number 2


Review Article

Research Article

Research Article

Research Article

Investigation of Ocular Bioactivation Potential and the Role of Cytochrome P450 2D Enzymes in Rat

, 11(2): 102 - 110

Jennifer L. Dumouchel*, Upendra A. Argikar, Jaimie Spear, Ann Brown, Christine E. Dunne, Valerie M. Kramlinger, Amanda L. Cirello and Mithat Gunduz

DOI: 10.2174/1872312811666170911122919

Research Article

The Effects of Drug Metabolizing Enzyme Inhibitors on Hepatic Efflux and Uptake Transporters

, 11(2): 111 - 118

Jonathan Cheong, Jason S. Halladay, Emile Plise, Jasleen K. Sodhi and Laurent Salphati*

DOI: 10.2174/1872312811666171010101248

Research Article

Research Article

Effect of CYP2D6 Poor Metabolizer Phenotype on Stereoselective Nebivolol Pharmacokinetics

Carolina P Vieira, Daniel V Neves, Eduardo B Coelho and Vera Lucia Lanchote*

View Abstract

Evaluation of the Effect of Uremic Serum on Hepatic Reductase Functional Expression

Osama Y. Alshogran*, Esra`a F. Al-Obaidi, Belal A. Al-Husein and Ashraf O. Oweis

View Abstract

Evaluation of Herb-Drug Interaction of SynacinnTM and Individual Biomarker through Cytochrome 450 Inhibition Assay

Fadzilah Adibah Abd Majid*, Nur Syukriah Ab Rahman, Effendy Abd Wahid , Ain Nabihah Zainudin , Siti Nurazwa Zainol , Hassan Fahmi Ismail, Tet Soon Wong, K. Vijaya Bhargava, Nirbhay Kumar Tiwari and Sanjeev Giri

View Abstract View on PubMed

LC-MS/MS Identification and Structural Characterization of Main Biodegradation Products of Nitroproston - A Novel Prostaglandin-based Pharmaceutical Compound

Natalia Vladimirovna Mesonzhnik*, Natalia Moskaleva, Ksenia Shestakova, Ksenia Kurynina, Pavel Baranov, Natalia Gretskaya, Igor Serkov, Igor Lyubimov, Vladimir Bezuglov and Svetlana Appolonova

View Abstract View on PubMed

Utility of Pooled Cryopreserved Human Enterocytes as an In vitro Model for Assessing Intestinal Clearance and Drug-Drug Interactions

Zhengyin Yan*, Susan Wong, Jane Kelly, Hoa Le, Ning Liu, Mika Kosaka, Suzanne Tey, Peter Vuong and Albert Li

View Abstract

Human HepaRG Cells can be Cultured in Hanging-drop Plates for Cytochrome P450 Induction and Function Assays

, 2015; 9(1): 3 - 7

Norie Murayama, Takashi Usui, Nicky Slawny, Christophe Chesne and Hiroshi Yamazaki

DOI: 10.2174/1872312809666150119104806

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