Contents

Current Topics in Medicinal Chemistry, Volume 9 - Number 13


Cancer and Virus Leads by HTS, Chemical Design and SEA Data Mining

, 9(13): 1159 - 1171

Pahk Thepchatri, Jaeki Min, Thota Ganesh, Yuhong Du, Iestyn Lewis, Serdar Kurtkaya, Andrew Prussia, Lian Li, Blossom Sneed, Richard K. Plemper, Haian Fu, Dennis C. Liotta, James P. Snyder, Raymond Dingledine and Aiming Sun


DOI: 10.2174/156802609789753581


Small-Molecule Modulators of the NF-κB Pathway Newly Identified by a Translocation-Based Cellular Assay

, 9(13): 1172 - 1180

Yuli Xie, Alison Rinderspacher, Yidong Liu, Gangli Gong, Deborah H. Smith, Michael Wyler, Lars Branden and Shi-Xian Deng


DOI: 10.2174/156802609789753617


The Pilot Phase of the NIH Chemical Genomics Center

, 9(13): 1181 - 1193

Craig J. Thomas, Douglas S. Auld, Ruili Huang, Wenwei Huang, Ajit Jadhav, Ronald L. Johnson, William Leister, David J. Maloney, Juan J. Marugan, Sam Michael, Anton Simeonov, Noel Southall, Menghang Xia, Wei Zheng, James Inglese and Christopher P. Austin


DOI: 10.2174/156802609789753644




Discovery and Development of a Potent and Highly Selective Small Molecule Muscarinic Acetylcholine Receptor Subtype I (mAChR 1 or M1) Antagonist In Vitro and In Vivo Probe

, 9(13): 1217 - 1226

C. David Weaver, Douglas J. Sheffler, L. Michelle Lewis, Thomas M. Bridges, Richard Williams, Natalia T. Nalywajko, J. Phillip Kennedy, Matthew M. Mulder, Satyawan Jadhav, Leslie A. Aldrich, Carrie K. Jones, Joy Marlo, Colleen M. Niswender, Matthew M. Mock, Fang Zheng, P. Jeffrey Conn and Craig W. Lindsley


DOI: 10.2174/156802609789753635




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